Showing 1 - 20 results of 40,816 for search '(( 50 ((_ decrease) OR (a decrease)) ) OR ((( 200 c decrease ) OR ( _ wt decrease ))))*', query time: 1.04s Refine Results
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    GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

    Published 2017
    “…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”
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    Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

    Published 2015
    “…G–I; Myelin sheaths in the unlesioned hemispheres of Scribble cKO corpora callosa were thicker than those observed in wild-type animals, with both mean g-ratio (G; WT: 0.761 ± 0.010, cKO: 0.675 ± 0.011) and the intercept of the best-fit line (H; WT: slope = 0.240 ± 0.029, intercept = 0.634 ± 0.017, cKO: slope = 0.266 ± 0.022, intercept = 0.538 ± 0.012) being significantly decreased. …”
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    Stability scores with refinement and no USM decreases. by Jedediah M. Singer (10331212)

    Published 2022
    “…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC<sub>50</sub> predictions.…”
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    Stability scores with refinement, no USM decreases, no W. by Jedediah M. Singer (10331212)

    Published 2022
    “…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC<sub>50</sub> predictions and neither guided nor random substitutions are allowed to change amino acids to tryptophan.…”
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    Stability scores with refinement, no USM decreases, no AFILMVWY. by Jedediah M. Singer (10331212)

    Published 2022
    “…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC<sub>50</sub> predictions and neither guided nor random substitutions are allowed to change amino acids to alanine, phenylalanine, isoleucine, leucine, methionine, valine, tryptophan, or tyrosine.…”
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    Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues. by Kumaraswamy Naidu Chitrala (612025)

    Published 2014
    “…<p>Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues.…”