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Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…<p>(A) Lysates from strains in stationary phase (A<sub>600</sub>>5.0) were subjected to native gel electrophoresis followed by an in-gel activity assay with the fluorogenic proteasome substrate Suc-LLVY-AMC. …”
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Decreased oscillatory flow decreases <i>klf2a</i> expression.
Published 2009“…(L) Quantitative RT-PCR showing the expression level of several flow-responsive genes after lidocaine treatment. <i>klf2a</i> expression is significantly decreased after 6 and 10 h of treatment and is restored by incubation at 34°C; 100% of expression corresponds to a normal expression level. …”
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<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays.
Published 2021“…The respective curves showed a decreased repopulation potential for all three cohorts of <i>Kdm6a</i> conditional KO mice, which was most pronounced in KO-F mice. …”
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Loss of C9orf72 decreases mTOR activation.
Published 2016“…C9orf72-/- MEF cells show a decrease in p-S6K1 when compared with wild-type cells. …”
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Blockade of mTORC2 decreased TRPC6-dependent calcium influx in podocytes (confocal microscopy).
Published 2014“…<p>(A) The podocytes were imaged at 0 seconds before the addition of hyperforin, a specific agonist of TRPC6, to record the baseline fluorescence. …”
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Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…<b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …”
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