Intrathecal delivery of IL-6 increases cAMP and AC levels and decreases PDE level in the sensorimotor cortex. by Ping Yang (56755)

L665W decreased AR5A binding to H77/JFH1 particles and to the E1/E2 complex in H77/JFH1 infected cells, but did not alter receptor dependency. by Rodrigo Velázquez-Moctezuma (3776023)

JTXK granule decreased the body weight and food intake in T2DM KKAy mice. by Na Yu (151735)

Potency of CCh (pEC₅₀) (dark blu) and atropine (pA₂) (light blu) on ileum (a) and on distal colon (red) and (pink) respectively. by Rita Aldini (92787)

“…Carbachol pEC₅₀ decreased by 3.80 times in the ileum and 1.58 times in the colon and Atropine p<i>A</i>₂ was reduced by 1.86 and 1.12 times respectively in the ileum and the colon, compared with the corresponding intestinal segments of control mice. …”

Increased p27Kip1 and decreased phosphorylated p27Kip1 at S10 and T198 by lowering H₂O₂ levels. by Irene L. Ibañez (137874)

The point mutants E559A, E563A and K567A display altered DNA-binding kinetics. by Bettina Hüntelmann (566945)

“…(G, H) Reduced nuclear export kinetics of STAT1-E559A and -E563A. HeLa cells expressing GFP-tagged wild-type or mutant STAT1 (scale bar 10 µm) were prestimulated for 45 min with IFNγ to induce nuclear accumulation (top panel) and then treated for 6 min in the presence of 50 µg/ml digitonin in ice-cold transport buffer (bottom panel). …”

Long-term viral suppression. by Sulav Duwal (152805)

Kaplan-Meier graph illustrating cardiovascular mortality in participants with ischemic heart disease during a follow-up period of 12 years of those supplemented with selenium and c... by Urban Alehagen (796660)

Pictorial view of some highly poisonous plants based on their LD50 values and respondent scores. by Faisal Rasool (12530732)

The Impact of Prophylactic Dexamethasone on Nausea and Vomiting after Thyroidectomy: A Systematic Review and Meta-Analysis by Zhenhong Zou (645858)

“…The meta-analysis demonstrated a significant decrease in the incidence of PONV (RR 0.52, 95% CI 0.43 to 0.63, <i>P</i><0.00001), the need for rescue anti-emetics (RR 0.42, 95% CI 0.30 to 0.57, <i>P</i><0.00001), post-operative pain scores (WMD –1.17, 95% CI –1.91 to –0.44, <i>P</i> = 0.002), and the need for rescue analgesics (RR 0.65, 95% CI 0.50–0.83, <i>P</i> = 0.0008) in patients receiving dexamethasone compared to placebo, with or without concomitant antiemetics. …”

Binding of serum ficolin-A to microorganisms. by Tina Hummelshøj (237744)

“…After incubation of the bacteria (1×10⁸ cells) with serum diluted 1∶50 in Barb-T buffer, the concentration of residual ficolin-A was estimated on acBSA coated polystyrene plates. …”

Structural-level tibial mechanical properties (mean ± SD). by Michael A. Friedman (2578648)

Proximal tibial trabecular architecture measures (mean ± SD). by Michael A. Friedman (2578648)

Cardamonin decreased the content of free fatty acids and the activity of CPT-1. by Peiguang Niu (17044532)

The differences between 8-week-old K14-VEGF mice and WT mice. by Xuguo Wang (839264)

Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

Fig 2 - by Benazir Hodzic-Santor (14593183)

A Sensitive Water-Soluble Reversible Optical Probe for Hg²⁺ Detection by Sayani Das (5116985)

“…The resultant molecule <b>qHCM</b> afforded a distinct reversible change in the absorption features and a concomitant visible color change upon binding to Hg²⁺ ions, leading to a highly water-soluble mercury sensor with a 10 ppb detection limit. …”

A Sensitive Water-Soluble Reversible Optical Probe for Hg²⁺ Detection by Sayani Das (5116985)

“…The resultant molecule <b>qHCM</b> afforded a distinct reversible change in the absorption features and a concomitant visible color change upon binding to Hg²⁺ ions, leading to a highly water-soluble mercury sensor with a 10 ppb detection limit. …”

RNA-Seq analysis of MCF10A and DCIS models (<i>A</i>) Differential interference contrast (DIC) images of 12-day 3D rBM overlay cultures of MCF10A, MCF10.DCIS, SUM102, and SUM225 ce... by Hitchintan Kaur (113418)

“…There are a total of 295 genes that are consistently differentially expressed between the MCF10A and the three DCIS models: MCF10.DCIS, SUM102 and SUM225. …”