Effect of METTL3 and WTAP depletion in <i>Toxoplasma</i>. by Michael J. Holmes (3689758)

Expression and distribution of p-JNK and JNK proteins in the P7 rat brain after HI as detected by Western blot analysis and fluorescence immunolabeling. by Deyuan Li (769599)

“…Total JNK protein was not obviously changed at different time points compared with sham controls (A). However, p-JNK protein levels transiently decreased at 0.5 h, increased at 6 and 24 h, peaked at 48 h, and lasted until 72 h (A). …”

Image_2_TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.tif by Rongkun Li (6286547)

“…Tripartite motif-containing 50 (TRIM50) is a member of the TRIM family, but little is known regarding its expression and potential functional roles in cancer. …”

Image_1_TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.tif by Rongkun Li (6286547)

“…Tripartite motif-containing 50 (TRIM50) is a member of the TRIM family, but little is known regarding its expression and potential functional roles in cancer. …”

Image_3_TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.tif by Rongkun Li (6286547)

“…Tripartite motif-containing 50 (TRIM50) is a member of the TRIM family, but little is known regarding its expression and potential functional roles in cancer. …”

Effect of MMP9 on periostin expression. by Nabila Djaziri (17537499)

FcRn KO alters lysotracker staining and LAMP1 and cathepsin B expression in podocytes. by George Haddad (470789)

Morphometric data of multipolar interneurons. by Janine R. Neumann (6330863)

Enhanced glycolysis promotes replication of SVA. by Huizi Li (6241586)

HI promotes FOXO3a dephosphorylation, which induces FOXO3a translocation into the nucleus and upregulates the expression of Bim and CC3. by Deyuan Li (769599)

“…However, p-FOXO3a levels decreased from 0.5 to 48 h and returned to baseline at 72 h after HI (A). …”

Piperhancins A and B, Two Pairs of Antineuroinflammatory Cycloneolignane Enantiomers from <i>Piper hancei</i> by Fan Yang (1413)

“…Among all of the isolates, compounds (+)-<b>1</b>, (−)-<b>1</b>, (+)-<b>2</b>, (−)-<b>2</b>, and (+)-<b>3</b> could significantly inhibit the production of nitric oxide secreted by lipopolysaccharide (LPS)-induced neuroinflammation in BV-2 microglial cells, with IC₅₀ values of 1.1–26.3 μM. In addition, compound (−)-<b>1</b> could decrease the mRNA levels of iNOS, IL-6, and TNF-α induced by LPS in BV-2 microglial cells.…”

Majority-rule tree inferred from the combined data set of embalonurid bats through a partitioned Bayesian analysis. by Alejandro José Biganzoli-Rangel (15411862)

AZ2.0 by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, <br>respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of <br>valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the <br>percentage repeat, resulted due to removal of mis-assembly and closure of gaps fromover the earlier <br>assembly (v1.0). …”

Inhibition of Akt but not Erk signaling is synergistic with atorvastatin. by Colin H. Beckwitt (2037196)

Video_1_Autologous Fractionated Adipose Tissue as a Natural Biomaterial and Novel One-Step Stem Cell Therapy for Repairing Articular Cartilage Defects.MP4 by Qi Li (67548)

Pelvis and femur shape prediction using principal component analysis for body model on seat comfort assessment. Impact on the prediction of the used palpable anatomical landmarks a... by Léo Savonnet (7314200)

“…Results also show that the PCA based method is a good alternative to predict hip and lumbosacral joint centers with an average error of 5.0 and 9.2 mm respectively.…”

Enzyme Active Site Loop Revealed as a Gatekeeper for Cofactor Flip by Targeted Molecular Dynamics Simulations and FRET-Based Kinetics by Sophie Rahuel-Clermont (6235601)

“…To monitor cofactor movements within the active site, we used an intrinsic fluorescence resonance energy transfer signal between Trp177 and the reduced nicotinamide moiety to kinetically track the flip during the catalytic cycle of retinal dehydrogenase 2 (ALDH1A2). Decreasing loop flexibility by substituting Ala for Gly271 drastically reduced the rate constant associated with this movement that became rate-limiting. …”

Understanding the Reactivity, Selectivity, and Deactivation of Frustrated Lewis Pairs for Semihydrogenation of Acetylene by Jingyun Ye (1289649)

“…The catalytic cycle consists of three steps: (1) alkyne insertion, (2) H₂ heterolysis, and (3) intramolecular protonation. …”

Understanding the Reactivity, Selectivity, and Deactivation of Frustrated Lewis Pairs for Semihydrogenation of Acetylene by Jingyun Ye (1289649)

“…The catalytic cycle consists of three steps: (1) alkyne insertion, (2) H₂ heterolysis, and (3) intramolecular protonation. …”

Propensity-score matched open aortic group. by Tomi Obafemi (12328433)

“…There was a decrease in post-op LOS, post-op VAP, and post-op UTI, although statistical significance was not attained.…”