Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…S5</a>). Orange boxes mark regions with peaks appearing at 2 h TSA and not further increasing, or even decreasing, at 6 h (MALAT1 peaks). …”

Image1_Association between coenzyme Q 10-related genetic polymorphisms and statin-associated myotoxicity in Korean stroke patients.PNG by Yoon-A Park (18512715)

“…Patients with COQ2 rs4693075 G allele, COQ3 rs11548336 TT genotype, and COQ5 rs10849757 A allele had a 2.9-fold (95% CI: 1.6–5.3), 1.9-fold (95% CI: 1.1–3.5), and 3.3-fold (95% CI: 1.5–8.3) higher risk of SRM, respectively.…”

Table1_Association between coenzyme Q 10-related genetic polymorphisms and statin-associated myotoxicity in Korean stroke patients.DOCX by Yoon-A Park (18512715)

“…Patients with COQ2 rs4693075 G allele, COQ3 rs11548336 TT genotype, and COQ5 rs10849757 A allele had a 2.9-fold (95% CI: 1.6–5.3), 1.9-fold (95% CI: 1.1–3.5), and 3.3-fold (95% CI: 1.5–8.3) higher risk of SRM, respectively.…”

Differential Regulation of Extracellular Matrix and Soluble Fibulin-1 Levels by TGF-β₁ in Airway Smooth Muscle Cells by Ling Chen (25698)

“…In some experiments, cycloheximide (0.5 µg/ml) was used to assess the regulation of FBLN-1 production. …”

Kinases are recruited to the signaling complex by alternative N-t localization domains. by Paloma M. Sato (672126)

“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”

Effect of SARS-CoV-2 Infection and Infection Severity on Longer-Term Glycemic Control and Weight in People With Type 2 Diabetes by Rachel Wong (5544899)

Low- and High-Volume of Intensive Endurance Training Significantly Improves Maximal Oxygen Uptake after 10-Weeks of Training in Healthy Men by Arnt Erik Tjønna (416233)

“…<div><p></p><p>Regular exercise training improves maximal oxygen uptake (VO_2max), but the optimal intensity and volume necessary to obtain maximal benefit remains to be defined. A growing body of evidence suggests that exercise training with low-volume but high-intensity may be a time-efficient means to achieve health benefits. …”

Data_Sheet_1_Immediate and long-term electrophysiological biomarkers of antidepressant-like behavioral effects after subanesthetic ketamine and medial prefrontal cortex deep brain... by Matthew Bergosh (18854590)

“…</p>Results<p>We found that the depression-like behavioral and weight effects of CORT correlated with a decrease in aperiodic-adjusted theta power (5–10 Hz) and an increase in sample entropy during the administration phase, and an increase in theta peak frequency and a decrease in the aperiodic exponent once the depression-like phenotype had been induced. …”

Identification of PFD0495c as a candidate gene linked to sphingolipid synthesis. by Pamela A. Tamez (222157)

“…(ii) Dendrogram of microarray data sets from two biological replicates showing that of the five conserved genes of the Hiller secretome validated to be exported <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000118#ppat.1000118-vanOoij1" target="_blank">[15]</a>, only two are regulated by PPMP: 3-fold increase in PFD0495c(**), 2-fold decrease in PFC0435w(*). …”

<i>Vg</i> expression regulates Lp-mediated accumulation of lipids via TOR signaling. by Iryna Stryapunina (17867390)

“…(F) Fold change in free amino acid levels in the fat bodies of ds<i>LacZ</i> and ds<i>Vg</i> females before blood meal and at 12h, 24h and 48h PBM; each dot is representative of five ovaries; N = number of samples of five tissues, pooled from three biological replicates (REML variance component analysis by timepoint: ** = p < 0.01). …”

Effects of metalloporphyrins on Cisplatin induced nitrative stress in mice. by Hao Pan (173271)

“…FeTMPyP and MnTBAP treatments lead to reduced protein nitration similar to vehicle level (n = 4–5/each group; p<0.01). Panel B: Quantitative measurement of protein nitration also demonstrated 3.9 fold increased by cisplatin and the protein nitration is decreased to 1.5 and 1.4 fold for FeTMPyP and MnTBAP treated groups respectively. …”

Evidence for an HSF-1–dependent thermostat in WT animals. by Laetitia Chauve (8600553)

“…The number of GFP-positive neurons increases by 6.6-fold from 15°C to 20°C; 16-fold from 15°C to 25°C; and 2.5-fold from 15°C to 20°C. …”

Status of peritubular myoid cells in <i>Wt1</i>^SC-cKO testis during fetal mouse testis development. by Qing Wen (808516)

“…Each bar is a mean±SEM of <i>n</i> = 3 mice. *, <i>P</i><0.05; **, <i>P</i><0.01.…”

Table 1_Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings.do... by Mostafa M. Rady (14004633)

“…<p>Abiotic stress significantly damages crops, reducing global yields by over 50%. Among these challenges, salt stress poses a critical constraint that severely affects the growth, productivity, and quality of soybeans in various regions worldwide. …”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

Image_2_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…(B) The number of bands of bridging fibrosis per high power field were counted in images obtained at 100× magnification after Sirius red staining. There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…<p>(<b>A</b>) Proximity ligation assay for the analysis of ILK/kindlin-1 interaction in COLXVI and mock control cells (scale bar equals 50 µm). …”