Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…Thermal energy in this cycle enables noncovalent interactions to reconfigure the nanostructures into the thermodynamically preferred long nanofibers, a repair process that is impeded by kinetic traps. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…Thermal energy in this cycle enables noncovalent interactions to reconfigure the nanostructures into the thermodynamically preferred long nanofibers, a repair process that is impeded by kinetic traps. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…Thermal energy in this cycle enables noncovalent interactions to reconfigure the nanostructures into the thermodynamically preferred long nanofibers, a repair process that is impeded by kinetic traps. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…Thermal energy in this cycle enables noncovalent interactions to reconfigure the nanostructures into the thermodynamically preferred long nanofibers, a repair process that is impeded by kinetic traps. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…Thermal energy in this cycle enables noncovalent interactions to reconfigure the nanostructures into the thermodynamically preferred long nanofibers, a repair process that is impeded by kinetic traps. …”

Overexpression of TNFAIP9 suppressed inflammation in mouse peritoneal macrophages caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 inhibited the TNF-α-induced inflammation in HK-2 cells. by Ying Chen (9697)

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

“…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”

WTP for a publicly provided HIS in the absence or presence of corruption. by Mireia Jofre-Bonet (728653)

Semi-log plot of the FIFA countries ranked by their decreasing “order of importance” through the FIFA coefficient; the best 5-parameter function, Eq (5), is shown. by Marcel Ausloos (748325)

<i>c-REL</i> knockout leads to significantly decreased expression levels of NF-κB family member and cell cycle-associated genes. by Carsten Slotta (4326091)

“…<p><b>A:</b> qPCR analysis showing significantly decreased mRNA levels of NF-κB family members <i>RELA</i>, <i>NFKB1 (p50)</i>, <i>NFKB2</i> (<i>p52)</i>, <i>IKBKE</i> and <i>TBK1</i> in <i>c-REL</i> knockout cells compared to wildtype cells. …”

Multiscale Macromolecular Simulation: Role of Evolving Ensembles by A. Singharoy (2032393)

“…Accuracy improves with the square root of the number of historical timesteps included in the calculation. As a result, CPU usage can be decreased by a factor of 3–8 without loss of accuracy. …”

Multiscale Macromolecular Simulation: Role of Evolving Ensembles by A. Singharoy (2032393)

“…Accuracy improves with the square root of the number of historical timesteps included in the calculation. As a result, CPU usage can be decreased by a factor of 3–8 without loss of accuracy. …”

Multiscale Macromolecular Simulation: Role of Evolving Ensembles by A. Singharoy (2032393)

“…Accuracy improves with the square root of the number of historical timesteps included in the calculation. As a result, CPU usage can be decreased by a factor of 3–8 without loss of accuracy. …”

Decreased glycosylated α-DG and laminin levels distal to the glial dome in <i>Large</i>^{<i>myd/myd</i>} mice. by Shigefumi Morioka (8893511)

Renin–angiotensin–aldosterone system inhibition with losartan significantly inhibited transforming growth factor-β1/Smads pathway and decreased Snail expression in vitro. by Chiao-Yin Sun (174213)

“…<p>A: ELISA analysis showed that losartan (1, 10, and 100 uM) significantly decreased the transforming growth factor-β1 concentration in the culture medium of PKSV cells treated with indoxyl sulfate (IS) (50 mg/L) and <i>p</i>-cresol sulfate (PCS) (50 mg/L). …”

Measurements of TA muscle CSA at the step-level section located 5.5 mm deep from the anterior edge of the muscle at 2 weeks and 4 weeks. by Jinjin Ma (3937364)

Aliskiren (Ali) decreased expression of angiotensin II (Ang II) and attenuated steatosis and inflammation in the livers of mice fed with methionine choline deficiency (MCD) diet. by Kuei-Chuan Lee (383486)

The mean and variance of the cable length can be independently controlled within the antenna model. by Lishibanya Mohapatra (759979)

“…Parameters used for the polymerization and depolymerisation rate were <i>r</i> = 370 s^-1, <i>d</i> = 45 s^-1, <i>k</i>_<i>off</i> = 0.5 s^-1(red) and 50 s^-1(blue); for chosen values of <i>k</i>_<i>off</i>, the rate <i>w</i> was calculated from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004160#pcbi.1004160.e005" target="_blank">Eq 1</a> for the mean length. …”

Inverse Relationship between IGF-1 induced Cyr61 upregulation and decreased E-cadherin and FOXO1 expression is confirmed in two cell lines. by Suren Sarkissyan (388555)