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18161
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18162
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18163
Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia
Published 2012“…LPS-induced phosphorylation of p38 mitogen-activated protein kinase and stimulation of NF-κB-responsive luciferase reporter activity was also decreased in Lrrk2-KD cells. Interestingly, the decrease in NF-κB transcriptional activity measured by luciferase assays appeared to reflect increased binding of the inhibitory NF-κB homodimer, p50/p50, to DNA. …”
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18164
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18165
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18166
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18167
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18168
Impact of loss of <i>Hes1</i> on differentiation and proliferation in the second heart field.
Published 2013“…(E) Western blot of microdissected heart and ventral pharyngeal regions of <i>Hes1</i><sup>+/+</sup> and <i>Hes1</i><sup>−/−</sup> embryos showing elevated p27<sup>kip1</sup> protein levels in the absence of Hes1. Scale bars (A): 50 µm; (B): 100 µm; (D) 50 µm.</p>…”
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18169
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18170
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18171
data_sheet_1.docx
Published 2018“…These findings add to the growing evidence that CRP has important biological effects even in the absence of an acute phase response, i.e., CRP acts as a tonic suppressor of the adaptive immune system. …”
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18172
HepG2 cells clear LPS in LDLR-dependent manner.
Published 2016“…Scrambled siRNA was reversely transfected into HepG2 cells, than treated similarly as described above with PCSK9 as a complementary approach to decreasing LDLR. Data presented as mean fluorescence intensity, mean±SEM (n = 3). …”
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18173
Caffeine induces proteome-wide changes in a Rob-dependent manner.
Published 2025“…(C) Proteome-wide response to caffeine in <i>E. coli</i>. Volcano plot showing how -log<sub>10</sub>(p-value) relates to log<sub>2</sub>(fold-change) of caffeine treated compared to untreated cells. …”
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18174
Metabolic and neuronal origins of the intrinsic flavoprotein signal response.
Published 2016“…<p><b>(A)</b> Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI. …”
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18175
Temporal Trend in Young-Onset Type 2 Diabetes - the Macrovascular and Mortality Risk: Study of UK Primary Care Electronic Medical Records
Published 2020“…The incidence rates of ASCVD and ACM declined in people aged ≥50 years, but did not decrease in people <50 years. …”
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18176
Data_Sheet_1_Hybrid Gibbsite Nanoplatelet/Cellulose Nanocrystal Multilayered Coatings for Oxygen Barrier Improvement.PDF
Published 2019“…The measurement of the oxygen transmission rate (OTR) at 23°C and 50% RH showed that the oxygen barrier properties of the bare substrates could be significantly improved (e.g., 75% decrease of the OTR) after the deposition of such thin (<100 nm) multilayered hybrid films. …”
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18177
Sulfur supply effects on production and mineral nutrition of Tanzania guinea grass under barium levels in nutrient solution
Published 2021“…The combinations with high S and Ba levels resulted in a decrease of 1.7-fold in leaf area compared to combinations with high S without Ba. …”
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18178
TNFα stabilizes myocardin mRNA through MEK/MAPK and NF-κB pathways.
Published 2014“…<p>(<b>A</b>) VSMCs were serum-starved for 24 h and transcription was blocked using α-amanitin (50 µM). …”
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18179
Data_Sheet_1_Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase.DOCX
Published 2018“…</p><p>Methods: We developed a novel “floxed” mouse that, through the Cre-LoxP approach, allows for tamoxifen (TMX)-inducible and skeletal muscle-specific overexpression of the p55α subunit of PI3K (referred to as, ‘p55α-mOX’). …”
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18180
BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros.
Published 2013“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”