Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor by Beatrice Noce (16540800)

Subjects:

Topography of the relationship between the change in alpha power decrease and the change in M50 gating ratio. by Tzvetan Popov (315385)

“…B: Relationship between change in alpha power decrease (abscissa, negative values indicate improvement) and pre-to-post-training change in M50 gating ratio (ordinate, positive values indicate changes towards normal, that is, smaller gating ratio) by patient training group based on the ROI in 4A.…”

Sequence of <i>DpAP2</i> promoter. by Lingru Ruan (18995544)

“…Carotenoid biosynthesis was enhanced by <i>DpAP2</i> overexpression (1.4930 fold of control) and exogenous substances such as GA3 (1.5889 fold of control), which laid a foundation for massive accumulation of carotenoids in microalgae. …”

Cell adhesion to fibronectin is decreased with 50 µM 4N1K treatment. by Pascal Leclair (566971)

Fig 2 - by Henning Carstens (13132801)

Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover by Naoto Hori (767562)

“…By using the theoretical estimate (∝<i>√N</i> where <i>N</i> is the number of nucleotides) for folding free energy barrier, <i>k</i>_F data for both the RNAs are quantitatively fit using one-dimensional Kramers’s theory with two parameters specifying the curvatures in the unfolded basin and the barrier top. …”

Dose- and time-dependent effect of IL-13, IL-4, and TGF-β1 on benzamil-sensitive <i>I</i>_sc and TEER in HBECs. by Anusree Sasidharan (19226521)

Decreased β-cell mass in Hq mutant mice. by Fabienne T. Schulthess (13268705)

TR4 and TR9 decrease hepatoma cell viability at a lower TC50 than Sorafenib, SAHA or 5-Fluorouracil. by Nicole Lange (335740)

Reduced follicles, decreased ovulation and decreased fertilization of female Meox-2-cre/Separase S1121A mutant mice. by Juan Xu (225010)

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Substitution of a lysine residue at position 8 of two model 9mer H2-K^b epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>. by Irini Evnouchidou (375919)

“…<p><i>Panels </i><i>A</i><i> and </i><i>B</i>, peptides LSIINFEKL and the variant LSIINFEAL (both at 50 µM) were incubated with 7.8 nM of ERAP1 for 1 hr at 37°C and the products analyzed by RP-HPLC. …”

Subset of selected genes showing a ≥2-fold change decrease of expression in the <i>furA</i>-turning off strain AGcoaRFurA. by Andrés González (767802)

“…<p>Subset of selected genes showing a ≥2-fold change decrease of expression in the <i>furA</i>-turning off strain AGcoaRFurA.…”

3-HPA and the 10-fold diluted reuterin-containing supernatant significantly decreased the <i>S.</i> Typhimurium χ3339 population. by Rosemarie De Weirdt (320666)

Supplemental Table 1 Kinase Inhibitor Screen from Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Aden... by Brittany L. Allen-Petersen (14935217)

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Inhibition of SKI-1/S1P enzymatic activity using PF-429242 impairs activation of the SREBP pathway and correlates with a dramatic decrease in lipid droplet number and area. by Anastasia Hyrina (3860455)

KOR-agonist (U50'488) and MOR-agonist (DAMGO) decrease symptoms in OVA-allergic mice. by Swantje C. Duncker (154707)

Fold changes for all differentially expressed genes. by June Guha (14041154)

Quantified folding energy landscapes with and without interfacial binding. by Xiakun Chu (151393)