SLE-associated <i>rs2205960</i> predicted to be part of a decameric motif for NF-κB p65 (RELA). by Harinder Manku (434551)

Detoxification effects of long-chain versus a mixture of medium- and long-chain triglyceride-based fat emulsion on propafenone poisoning by Xusheng An (10461207)

“…<div><p>In the present study, we aimed to compare the detoxifying effects of two fat emulsions containing either long-chain triglyceride or a mixture of medium-chain and long-chain triglycerides in the propafenone-poisoned rat model. …”

Data_Sheet_1_Efficacy and Safety of Remimazolam for Procedural Sedation: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis.docx by Bo-Jyun Jhuang (11187882)

“…Compared with the use of midazolam, the utilization of remimazolam resulted in an increase in procedure success rate [odds ratio (OR) = 9.01, 95% confidence interval (CI): 2.35–34.57], a reduction in the application of rescue medication (OR = 13.58, 95% CI: 3.46–53.28), a decrease in time to recovery [minutes, weighted mean difference (WMD) = −5.70, 95% CI: −8.68 to −2.72], and a better cognitive recovery of Hopkins Verbal Learning Test-Revised (WMD = 5.22, 95% CI: 2.88–7.55). …”

Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration by Jeanette M. Metzger (8259900)

“…<div><p>Cardiac dysautonomia is a common nonmotor symptom of Parkinson’s disease (PD) associated with loss of sympathetic innervation to the heart and decreased plasma catecholamines. …”

Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats by X. Liu (589632)

“…<div><p>Galunisertib (LY2157299), a selective ATP-mimetic inhibitor of TGF-β receptor I (TGF-βRI), is the only known TGF-β pathway inhibitor. …”

Table 1_Propolis supplementation on inflammatory and oxidative stress biomarkers in adults: a systematic review and meta-analysis of randomized controlled trials.docx by Hossein Bahari (16704768)

“…This meta-analysis revealed that propolis consumption led to a significant decrease in C-reactive protein (CRP) (WMD: –1.23; 95%CI: –1.76, –0.69; p < 0.001), Interleukin-6 (IL-6) (WMD: –1.52; 95%CI: –2.10, –0.93; p < 0.001), Tumor necrosis factor-α (WMD: –1.15; 95%CI: –1.75, –0.55; p < 0.001), and Monocyte chemoattractant protein-1 (MCP-1) (WMD: –35.33; 95%CI: –50.28, –20.37; p < 0.001), and a significant increase in total antioxidant capacity (TAC) (WMD: 0.32; 95%CI: 0.12, 0.51; p = 0.001), Glutathione (GSH) (WMD: 4.71; 95%CI: 3.17, 6.25; p < 0.001), and Glutathione peroxidase (GPx) (WMD: 44.75; 95%CI: 5.10, 84.40; p = 0.02). …”

A Meta-Analysis of Anti-Vascular Endothelial Growth Factor Remedy for Macular Edema Secondary to Central Retinal Vein Occlusion by Peirong Huang (501361)

“…Secondary outcomes showed that a 90% and 77% decreased risk at 6 and 12 months for a loss of 15 letters or more. …”

Can tortoises facilitate the germination of plants with dry fruits? A simulation of the effects of Chelonoidis carbonarius (Testudines: Testudinidae) on the germination of Leucaena... by João Fabrício Mota Rodrigues (3149604)

Supplementary Material for: The risk of cardiovascular disease following aromatase inhibitor therapy for breast cancer in postmenopausal women: a systematic review and meta-analysi... by figshare admin karger (2628495)

“…However, there was a significant decrease in the risk of myocardial infarction (RR 0.77, 95% CI: 0.65-0.90, p<0.05) in the AI group when compared to no hormonal treatment. …”

Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies by Hadith Tangestani (6202022)

“…VDFs may increase serum 25(OH)D and BMD while decrease serum PTH levels. We did not find any beneficial effect of VDFs on BTM.…”

Table 1_Efficacy of submucosal administration of tramadol on acute pain following third molar surgery: a systematic review and meta-analysis.docx by Ahmad Salem Assari (20277900)

“…In addition, tramadol demonstrated a significant decrease in post-operative pain.</p>Conclusion<p>Submucosal tramadol is an efficient, safe, and dependable method for reducing post-operative acute pain, particularly in the first 6 h following impacted third molar surgery. …”

Identification and characterization of methicillin-resistant Staphylococcus spp. isolated from surfaces near patients in an intensive care unit of a hospital in southeastern Brazil by Luciano Freitas Fernandes (10372545)

“…The presence of the mecA gene was investigated using PCR. RESULTS: We observed that 44 out of the 50 sampling sites presented grown isolates in the methicillin-resistant Staphylococcus aureus medium. …”

Effectiveness of intermittent fasting to potentiate weight loss or muscle gains in humans younger than 60 years old: a systematic review by Cristian Sandoval (9940011)

Quantification of Membrane and Membrane-Bound Proteins in Normal and Malignant Breast Cancer Cells Isolated from the Same Patient with Primary Breast Carcinoma by Xiquan Liang (1867900)

“…More than 50% of all major drug targets are membrane proteins, and their role in cell−cell interaction and signal transduction is a vital concern. …”

Quantification of Membrane and Membrane-Bound Proteins in Normal and Malignant Breast Cancer Cells Isolated from the Same Patient with Primary Breast Carcinoma by Xiquan Liang (1867900)

“…More than 50% of all major drug targets are membrane proteins, and their role in cell−cell interaction and signal transduction is a vital concern. …”

A Randomized Controlled Study on the Effects of Bisoprolol and Atenolol on Sympathetic Nervous Activity and Central Aortic Pressure in Patients with Essential Hypertension by Wei-Jun Zhou (456887)

“…The augmentation index at a HR of 75 bpm (AIxatHR75) was significantly decreased (29%±11% to 25%±12%; <i>P</i> = 0.026) in the bisoprolol group only. …”

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer by George M. Philips (206900)

“…Hepatocellular carcinoma (HCC) emerges spontaneously in such mice by 50–60 weeks of age, providing a model of fibrosis-associated hepatocarcinogenesis. …”

Table 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…Furthermore, elevated NLR significantly impacted disease-free survival (HR: 1.79, 95% CI: 1.18-2.71; p = 0.006), recurrence rates (HR: 2.18, 95% CI: 1.36-3.51; p = 0.001), recurrence-free survival (HR: 3.05, 95% CI: 1.79-5.19; p < 0.0001), and the incidence of distant metastases (HR: 1.73, 95% CI: 1.20-2.50; p = 0.003).</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”

Data_Sheet_1_Association of plasma propionate concentration with coronary artery disease in a large cross-sectional study.PDF by Nikolaos Pagonas (306007)

“…This study aimed to evaluate the role of propionate, the most important SCFA in patients with CAD.</p>Methods<p>We performed a cross-sectional study enrolling patients admitted for invasive coronary angiography in two university hospitals in Germany. …”

Dental developmental complications in pediatric hematopoietic stem cell transplantation patients: A study using CMC clinical data warehouse by Jaehyun Kim (14009967)

“…Regression analysis demonstrated that a younger age at initial chemotherapy was a risk factor for tooth agenesis and microdontia.  …”