Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

“…(<b>G-I)</b> One way to appreciate the power of the latent drive force provided by LOF alleles that segregate independently of the <i>Rescue</i>/Cargo is to consider a split^50cM <i>ClvR</i> population in which a <i>Rescue</i>/Cargo/gRNAs with no fitness cost has spread to allele fixation, the Cas9 driver chromosome has been completely eliminated (as would happen during drive if the presence of Cas9 resulted in a fitness cost to carriers, discussed below), and all endogenous copies of the essential gene have been rendered LOF (generation 0 in <b>G-I</b>). …”

Comparison of mean differences in temperature decreases. by Hans-Jörg Gillmann (8460585)

IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Fluid loss and hydration in CON (n = 22) and HOT (n = 17) surgeries; Decrease in body mass in kg (A), decrease in body mass in % of total body mass (B), rate of decrease in body ma... by Zehra Palejwala (7507409)

HSF2 binds the ORF50 promoter and remodels the local chromatin landscape. by Lorenza Cutrone (21144285)

Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. by Georg Oberhofer (3401438)

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Polypropylene (PP) is widely used in commodity applications owing to its chemical stability, mechanical properties and low cost. However, almost 50% of the produced PP ends up as postconsumer waste (PCW) within a short period of usage. …”

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Polypropylene (PP) is widely used in commodity applications owing to its chemical stability, mechanical properties and low cost. However, almost 50% of the produced PP ends up as postconsumer waste (PCW) within a short period of usage. …”

Temporal distributions of inscriptions and occupations using uniform 50-years-long timeblocks. by Vojtěch Kaše (6156971)

Population dynamics of <i>Killer-Rescue</i>/Cargo, ClvR and split^50cM <i>ClvR</i> for elements with different fitness costs, and introduction percentages. by Georg Oberhofer (3401438)

The apparent Ca²⁺ affinity of release is decreased by hydrophobic mutations. by Matthew R. Bowers (8423115)

“…The significant rightward shift in the curve (EC50, non overlapping confidence intervals) indicates a decrease in the apparent Ca²⁺ affinity of neurotransmitter release.…”

Drugs IC₅₀s data during the study period. by Winnie Okore (14139712)

H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. by Laura L. Stafman (6577184)

“…There was a trend toward decreased Ki67 staining in FTY720-treated tumors (p = 0.29). …”