<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> by Dmitri Samovski (305400)

“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”

Cell-tracking analysis of ME180 cells upon PilC1- or PilC2-mediated infection. by Philippe C. Morand (260255)

“…<p>ME180 cells were infected (MOI 50) with strains Nm604a or Nm910f that express constitutively either PilC1 or PilC2, and tracked throughout the experiment. …”

DataSheet1_Investigations of potential non-amino acid SNAT2 inhibitors.docx by Sebastian Jakobsen (17732745)

“…In contrast to the previous publication, MMTC showed no inhibition of SNAT2-mediated ³H-Gly uptake in PC-3 cells at a concentration of 1 or 5 μM, despite a published IC₅₀ of 0.8 µM. …”

Insecticide activity and toxicity of the three <i>Alpinia</i> species essential oils against stored-product insects by Jia-Zhu Wang (17498633)

“…While the EO of <i>A. oxyphylla</i> rhizome (EOAOR) exhibited the highest contact toxicity to <i>L. serricorne</i> (LD₅₀ = 8.06 μg/ adult). …”

Sandwich ELISAs for isotype-specific detection of soluble rBFT1 and rBFT2 in buffer and in stool filtrate. by Saraspadee Mootien (3812851)

“…<p>(A) Microtiter plates were coated with 10 μg/ml of capture mAb 4G1 specific to rBFT1. …”

Shv activates βPS integrin signaling <i>in vivo</i>. by Joo Yeun Lee (3169611)

“…(B) Arrows point to extracellular Shv labeling in hub and GSC/CySC interface. …”

Economical analysis of the inclusion of flour residue of tucumã ("Astrocaryum vulgare", Mart) in the feeding of laying hens by João Paulo Ferreira RUFINO (4826637)

“…The cumulative feed intake showed significant differences (P<0.05) with the level of 6.27% had the highest cumulative consumption in level of 4.67% and the economic optimum point for consumption, with a reduction of up to R$ 31.268 in the production cost of rations considering the level of inclusion and higher level without inclusion. …”

Body weight development of male (upper curves) and female (lower curves) rats. by Matti Viluksela (321291)

Table_2_Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms.docx by Yasmin Silva Rizk (10195547)

“…Amentoflavone demonstrated activity on intracellular amastigotes in macrophages obtained from BALB/c mice (IC₅₀ 2.3 ± 0.93 μM). No cytotoxicity was observed and the selectivity index was estimated as greater than 10. …”

Table_1_Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms.docx by Yasmin Silva Rizk (10195547)

“…Amentoflavone demonstrated activity on intracellular amastigotes in macrophages obtained from BALB/c mice (IC₅₀ 2.3 ± 0.93 μM). No cytotoxicity was observed and the selectivity index was estimated as greater than 10. …”

Ketamine reduces cell adhesion. by Claire E. Hills (452020)

“…The former is known as the “detachment energy” (panel E) and the later is “maximum unbinding force” (panel F). Ketamine decreased the maximum unbinding force and the work of adhesion in a dose dependent manner compared to control. …”

Deficiency of tau protects against age-dependent neurodegeneration and memory loss measured by deficits in spontaneous alternations in AICD-Tg mice. by Kaushik Ghosal (244754)

“…<p>A. AICD-Tg mice exhibit decreased working memory as measured by deficits in spontaneous alternations at older ages. …”

IGF2 knockdown alters the cellular response to Taxol. by Jurriaan Brouwer-Visser (578686)

“…Taxol treatment of HEY-T30 shIGF2-p cells resulted in a higher percentage of apoptotic cells compared to treatment with vehicle (DMSO), and Taxol-induced apoptosis was significantly enhanced in HEY-T30 shIGF2 cells compared to HEY-T30 shScrambled, at this time point. …”

Biodiversity adaptation indicators averaged globally by partnership scale. by William B. Monahan (313511)

“…Following basic tenets of conservation biology, partnerships promote climate change adaptation by increasing area (A) and environmental heterogeneity (B-D). They also decrease climate-area velocity (E,F) by increasing spatial variation in temperature or precipitation. …”

Changes in capability of cell invasion and alterations in expression of angiogenic, invasive, and survival factors in glioblastoma cells after photofrin based PDT. by Mrinmay Chakrabarti (284359)

“…A significant reduction in the number of invaded cells indicated the decrease in invasive capability of the cells after dose-dependent photofrin based PDT. …”

Optical coherence tomography angiography findings in malignant hypertensive retinopathy by Berna Dogan (5762903)

“…Visual acuity was 20/63 in the right eye and 20/50 in the left eye. Fundus examination revealed signs of hypertensive retinopathy; thus, a multidisciplinary approach was adopted for the diagnosis and treatment of this patient. …”

Confocal images showing inhibition of BrdU incorporation in BV-2 microglial cells treated with HDAC inhibitor. by Nimmi Baby (524594)

“…The number of BrdU positive cells (E,G);arrows) decreased at 24 h after HDAC inhibitor treatment. Scale bars: 50 µm. …”

FLCN is necessary for the VHL-mediated tumor suppression. by Prabhat Bastola (438804)

“…<p>ShRNA-induced knockdown of FLCN promotes tumor formation by 786-O cells with reconstituted VHL. <b>A.</b> Western blot demonstrating a decrease in FLCN protein expression in cells stably expressing three different FLCN shRNAs as compared to cells transfected with scramble (Scr) control. …”

EDCC analysis of circadian microarray data. by Pavlos Stephanos Bekiaris (4732863)

“…ZT0-ZT4 (morning), ZT4-ZT8 (midday), ZT8-ZT12 (evening), ZT12-ZT16 (early night), ZT16-ZT20 (midnight), ZT20-ZT0 (before dawn). B) Decrease of standard deviations of randomized CREs in percent plotted against the number of randomized CREs used (10, 50, 100, 500, and 1000 random CREs, respectively). …”

Numerical analysis of the effective stiffness of elastomeric bearing pads under precast beams for the limit load of lateral instability by L. C. REIS (8652054)

“…The increase in spans and initial imperfections causes a decrease in the rollover limit load. The lift off effect is aggravated as the lateral eccentricities increase. …”