Celastrol targets AR-ERG-p536 in T/E fusion expressing PCa cells at protein level. by Longjiang Shao (385841)

“…In groups in which Celastrol concentration is equal or higher than 0.5 µM, significant decreased AR and ERG as well as AR3 expression were seen. …”

In vitro analysis of virulence-attenuated Tn mutants. by Joanne Cummins (457912)

“…The mariner mutants in <i>prfB</i> and lmoH7858_0137 have a decreased ability to grow in a high salt environment compared to the wild-type strain. …”

Analysis of murinized H7858 <i>L. monocytogenes</i>. by Joanne Cummins (457912)

“…Under our conditions tested the murinized strain had a decreased ability to invade the Caco₂ cell line. …”

Illustrative cases of fractionated radiosurgery for large brain metastases. by Joo Whan Kim (3135003)

“…Radiosurgery was performed because of the post-operative recurrence and tumor abutting the transverse sinus. The 16.5 cm³ cerebellar mass with was treated with a marginal dose of 8 Gy targeted to the 50% isodose line in 3 consecutive daily fractions. …”

FIGURE 1 ANALYSED RAW DATA by Interacteam UNSW (5938655)

“…For GFP-tagged MyD88 TIRdomain, small fluctuations in intensity are recorded around the average fluorescence value, as expected for a low-order oligomer such as a dimer (for example, if 20 proteins are detected simultaneously, the exit/entry of a single protein causes a decrease/increase of signal of only 5%). …”

Immune response, blood parameters and growth performance in broiler fed reduced protein diet supplemented with β-hydroxy-β-methyl butyrate and conjugated linoleic acid by Ali Asghar Saki (5670092)

“…Treatments includes: 1) A normal-protein diet (NPD) was formulated according to the Ross 308 recommendation (2014) by corn and soybean meal, 2) A reduced-protein diet (RPD) was prepared with dietary protein reduced by 12 g kg-1 (1.2%) relative to the NPD, 3) HMB+ RDP, 4) CLA+RDP and 5) CLA+ HMB+ RDP. …”

<i>In vivo</i> overexpression of <i>AeTEP-1</i> impairs DENV infection. by Gong Cheng (11640)

“…<i>Ae</i>TEP-1 was detected with a V5-HRP mAb. The mock control was the empty vector transfected S2 cells. …”

Prdm8 alters layer formation in the neocortex. by Mayuko Inoue (516753)

“…<p>In utero electroporation of any one of control (pCAG-IRES-EGFP with pCAG-IRES-Puro; A), or Prdm8 gain-of-function (pCAG-IRES-EGFP with pCAG-Prdm8; B), or Prdm8 loss-of-function (pCAG-IRES-EGFP with pPrdm8sh#629; C) vectors were carried out at E12.5, and the brains were analyzed at P5. …”

Table plot of associations between cytokine levels and epidemiologic factors. by Song Yao (202481)

Modulation of body bend depth through NLP-12/CCK signaling is critical for local food searching. by Raja Bhattacharya (622660)

“…(<b>B</b>) Average body bend amplitude for the genotypes as indicated measured during an initial five minute time interval (0–5) immediately following removal from food and a second five minute time interval 30 minutes after removal from food (30–35). …”

Activation of mitoK_ATP channels increased the electrical coupling of directly coupled astrocytes in slice. by Jiangping Wang (281901)

“…<p>(<b>A</b>) Representative recordings of a recorded astrocyte pair after addition of DIZ, 5-HD, or both for 5 min. …”

Effects of cooperativity on effective energetic contribution of hotregions. by Rudi Agius (454506)

“…Effectively, the additive hotspot energy assumption results in hotregions contributing in a linearly increasing manner according to their size, the negative cooperativity assumption results in hotregions contributing in an increasing exponential-like manner as the hotregions increase in size, and the positive cooperativity assumption results in hotregions reaching a maximum contribution at around a hotregion size of 5, with their contribution decreasing beyond.…”

Disruption of RAR Function during Regeneration Causes Bud Malformations by Yuval Rinkevich (379284)

“…Histological sections reveal malformation of regenerating buds in RNAi treatments (F, arrow, compared to <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050071#pbio-0050071-g005" target="_blank">Figure 5</a>E and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050071#pbio-0050071-g005" target="_blank">5</a>F). …”

Serine 26 in the PomB Subunit of the Flagellar Motor Is Essential for Hypermotility of <i>Vibrio cholerae</i> by Petra Halang (561390)

“…By analyzing a large data set of individual tracks of swimming cells, we show that S26 located within the transmembrane helix of PomB is required to promote very fast swimming of <i>V</i>. …”

Image1_Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.TIF by Burong Feng (11661529)

“…In vivo, we revealed that the LHD, in different doses (6.25 mg/kg, 12.5 mg/kg, 25 mg/kg, 50 mg/kg), has a protective effect on stress physiological responses by assessing the body temperature of mice. …”

Table 1_Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis.docx by Xuan Wu (126953)

“…Following treatment, the TAC group demonstrated a significantly lower absolute count of CD3⁺CD4⁺ T cells compared to the GC group (663.4 ± 345.5 × 10⁶/L vs. 952.5 ± 513.9 × 10⁶/L, P = 0.030). …”

Signal pathway enrichment analysis. by Signe E. Cremer (7861373)

“…Proteins are ranked within a pathway from high to low frequency, and the pathways* are ranked according to the significance-level of enrichment (decreasing enrichment-level left to right). …”

Image2_Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.TIF by Burong Feng (11661529)

“…In vivo, we revealed that the LHD, in different doses (6.25 mg/kg, 12.5 mg/kg, 25 mg/kg, 50 mg/kg), has a protective effect on stress physiological responses by assessing the body temperature of mice. …”

Genetic and Epigenetic Changes in Chromosomally Stable and Unstable Progeny of Irradiated Cells by Janet E. Baulch (633703)

“…While no changes in DNA methylation were observed for the gene promoters evaluated, increased LINE-1 methylation was observed for two unstable clones (LS12 and CS9) and decreased Alu element methylation was observed for the other two unstable clones (115 and Fe5.0–8). …”

The absence of Pfd1 causes alterations in the intragenic distribution of RNA polymerase II. by Gonzalo Millán-Zambrano (460604)

“…<p><b>A.</b> Comparative distribution of total RNA polymerase II (as measured by Rpb3 ChIP) and active transcription (as measured by run-on) across genes, expressed as 3′/5′ ratios. …”