Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

The saturated fatty acid palmitate decreases viability and induces apoptosis in HUVECs. by Dustin M. Lee (8207457)

Nonmetric multidimensional scaling ordination of bryophytes on a matrix of 94 plots by 5 species groups along the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects:

Scatterplot of fold-change expression for B-cell-specific mRNA transcripts in the whole blood. by Luísa Camacho (5508251)

“…The horizontal gray bars indicate a 2-fold increase and decrease in expression compared to control. …”

IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

Increase in resistance grade is correlated with the loss of <i>in vitro</i> parasite infectivity and decreased cutaneous lesion size. by Jairo E. Perez-Franco (3166050)

Knockdown of factors in the 5′SS recognition complex U1 globally decreases intronic miRNA levels. by Maja M. Janas (200408)

Decreased bleomycin-induced apoptosis in hTERT transfected MLE cells. by Nissim Arish (736264)

“…(B) Flow cytometry analysis demonstrating decreased Annexin V staining in bleomycin-treated hTERT⁺ compared to hTERT^ctrl cells. …”

ROC analysis for differentiating bladder cancer patients from controls using the ucfDNA concentration before and after normalization by creatinine concentration in those samples wi... by Meihui Chen (1670020)

Effect of dexmedetomidine (5 μg∙kg⁻¹ or 50 μg∙kg⁻¹) at experimental recording (Protocol 1). by Yoichiro Kitajima (4319455)

Subjects:

Decreasing RhoB expression by siRNA transfection does not change Ad5wt attachment or internalization. by Dragomira Majhen (462312)

Nonmetric multidimensional scaling ordination of vascular plants in a matrix of 93 plots x 36 species along the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

Subjects:

Neutrophils adhered to the apical surface of polarized-MDCK cells augment AdV entry without decreasing the TER. by Poornima L. N. Kotha (701665)

VOC Alpha spike protein shows decreased proteolytic processing. by Daniela Niemeyer (199082)

Dexmedetomidine (Dex) reversed isoflurane-induced inhibition of Akt activity and decrease of Bcl-xL/Bad ratio in the hippocampus of P7 rats (n = 7 in each group). by Yujuan Li (554062)

Mean scores and 95% CIs according to SARS-CoV-2 infection status and work-related determinants. by A. H. Ayesha Lavell (16734002)

Ni causes a decrease in membrane sterols in A549 lung epithelial cells. by Amber R. Matha (19681603)

List of DEGs in S. aureus PS/Bac/317/16/W strain spiked PCs vs TSB with log2fold-change ≥ 2 or ≤ -2, p<0.05. by Basit Yousuf (630368)