Morphological and Physiological Response to Chronic Hyperexcitability, and Proposed “Inverse U” Model Response for Enhanced β-Cell Excitability by Maria Sara Remedi (376135)

“…Both Kir6.2[AAA] and heterozygous Kir6.2- and SUR1-KO mice (50%–70% decreased K_ATP activity with increased excitability) hypersecrete (grey circles, solid line) and are positioned on the “ascending limb” of the curve [<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0050206#pmed-0050206-b013" target="_blank">13</a>,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0050206#pmed-0050206-b014" target="_blank">14</a>,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0050206#pmed-0050206-b043" target="_blank">43</a>]. …”

SSO-mediated skipping of <i>HRAS</i> exon 2. by Anne-Mette Hartung (2795626)

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

DataSheet_1_Evidence on Efficacy and Safety of Chinese Medicines Combined Western Medicines Treatment for Breast Cancer With Endocrine Therapy.docx by Lu Li (14069)

“…There were no limitations on the languages. We extracted data from the included RCTs, assessed study quality, conducted meta-analyses by RevMan 5.4 and compared the pooled Risk Ratios (RR) or Mean Difference (MD) with 95% CIs.…”

MicroRNA-149 is downregulated in Alzheimer’s disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1 by Wenyan Du (9758108)

Isobaric mass tagging and triple quadrupole mass spectrometry to determine lipid biomarker candidates for Alzheimer's disease by Suzumi M. Tokuoka (8107817)

Clinical course of patient and drug resistance profile. by Atsuko Hachiya (233188)

“…After instruction on the use of antiretroviral drugs, the viral loads successfully decreased below the detection limit (<50 copies/ml). …”

Additional comparisons between testing strategies. by Lucia Cilloni (9720852)

“…(B) Comparison of both testing strategies shown in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1003456#pmed.1003456.g003" target="_blank">Fig 3</a>, by their impact on the incidence of drug-resistant TB (DR-TB) over time, at fixed 50% coverage. …”

Prediction of late response to DNA damage. by Sohyoung Kim (253617)

Image9.JPEG by Beatrice Bianchi (4920481)

Image6.JPEG by Beatrice Bianchi (4920481)

Image8.JPEG by Beatrice Bianchi (4920481)

Image7.JPEG by Beatrice Bianchi (4920481)

Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV‑1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutan... by Sheng Han (419184)

“…The antiviral activity of this compound was much higher than those of ETR and EFV against the WT, E138K, and K103N variants (EC₅₀ = 3.4, 4.3, and 3.6 nM, respectively), and the cytotoxicity was decreased while the selectivity index (SI) was increased. …”

Increased Insulin-like Growth Factor 1 Receptor Protein and Pro-survival Signal by let7c Modulation. by Jeong-Min Kim (168316)

RSPO1-LGR4-induced β-catenin activation is not mediated by GPCR signaling. by Heinz Ruffner (150990)

“…Cells were stimulated for 24 h as follows before luciferase values were determined as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0040976#pone-0040976-g002" target="_blank">Figure 2a:</a> Mock, medium; Iso, 1 uM Isoproterenol; RSPO1, 50 ng/ml RSPO1; RSPO1+Iso, 50 ng/ml RSPO1+1 µM Isoproterenol. …”

Image_1_FASN-Mediated Lipid Metabolism Regulates Goose Granulosa Cells Apoptosis and Steroidogenesis.TIF by Xi Chen (35903)

Dataset on the Chemical Modification of Ascorbic Acid (AA) to L-ascorbyl-6-palmitate (AP): A Novel Approach For Improved Antioxidant Therapy in Traumatic Brain Injury (TBI) by Umar Faruk Saidu (16446285)

“…The Means were computed from five replicates (n = 5) for each parameter. A statistical test, ANOVA was used to determine noteworthy differences between the means. …”

DataSheet_1_The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes.pdf by Sarah C. Moody (8925293)

“…RNA-Seq of gonocytes purified from E13.5 and E15.5 Inhba KO mice (activin A subunit knockout) identified 46 and 44 differentially expressed genes (DEGs) respectively, and 45 in the E13.5 Inha KO (inhibin alpha subunit knockout; increased activin A) gonocytes. …”

Table_1_Right and Left Ventricular Strain Patterns After the Atrial Switch Operation for D-Transposition of the Great Arteries—A Magnetic Resonance Feature Tracking Study.DOC by Barbara Elisabeth Ursula Burkhardt (6567515)

“…This physiology can be considered a model for the effects of long-term right ventricular pressure overload and of decreased left ventricular afterload. We aimed to determine the impact of these chronically altered loading conditions on myocardial deformation of the ventricles.…”