Image_4_The Indispensable Role of Histone Methyltransferase PoDot1 in Extracellular Glycoside Hydrolase Biosynthesis of Penicillium oxalicum.TIF by Yanan Li (94033)

“…<p>Histone methylation is associated with transcription regulation, but its role for glycoside hydrolase (GH) biosynthesis is still poorly understood. We identified the histone H3 lysine 79 (H3K79)-specific methyltransferase PoDot1 in Penicillium oxalicum. …”

Nafion-Mediated Proton Transfer Facilitates the Electroreduction of SO₂ to H₂S by Hui Liu (33624)

“…Here, we demonstrate an effective solution to alleviate the problem of insufficient supply of protons by employing Nafion polymer as the proton conductor to modified Cu catalysts surface, creating a proton-enriched layer to boost H₂S generation. …”

Image4.JPEG by Muhammad I. Waris (5093375)

“…The NlugCSP8 mRNA was also highly expressed in the abdomen of unmated 5-day brachypterous males and correlated to the age, gender, adult wing form, and mating status. …”

Table_1_Spatiotemporal Change of Net Primary Productivity and Its Response to Climate Change in Temperate Grasslands of China.XLS by Rong Ma (500564)

“…Based on MODIS data and monthly climate data during 2000–2020, this study explored the spatiotemporal changes in grassland NPP and its response to climate change in temperate grasslands of China. We found that the annual NPP over the entire China’s temperate grasslands increased significantly by 4.0 gC/m²/year from 2000 to 2020. …”

Prenylated Polyphenols from <i>Clusiaceae</i> and <i>Calophyllaceae</i> with Immunomodulatory Activity on Endothelial Cells by Caroline Rouger (1523164)

“…Here, 13 polyphenols belonging to 5 different chemical types of secondary metabolites (i.e., mammea coumarins, a biflavonoid, a pyranochromanone acid, a polyprenylated polycyclic acylphloroglucinol (PPAP) and two xanthones) were tested on resting and cytokine-activated EC cultures. …”

Image3_Respiratory support strategies in the prevention of bronchopulmonary dysplasia: A single center quality improvement initiative.jpeg by Heather White (6612848)

“…</p>Methods<p>Directed by a multidisciplinary respiratory QI team, we gradually implemented the following interventions to reach our aim: (1) early initiation of non-invasive ventilation in the delivery room, (2) initiation of caffeine prior to 24 h of life, (3) administration of early selective surfactant per a well-defined guideline, (4) continuation of non-invasive ventilation until 32 and 0/7 weeks corrected gestational age (CGA), and (5) a revision of the early selective surfactant guideline. …”

An Atypical Mitochondrial Carrier That Mediates Drug Action in <i>Trypanosoma brucei</i> by Juan P. de Macêdo (735541)

“…<i>brucei</i> bloodstream forms, we identified a member of the mitochondrial carrier family, TbMCP14, as a prime candidate mediating the action of a group of anti-parasitic choline analogs. …”

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration by Xinyi Zhang (36040)

Image_2_Bacteroides thetaiotaomicron Ameliorates Experimental Allergic Airway Inflammation via Activation of ICOS+Tregs and Inhibition of Th2 Response.tif by Wenhui Pang (394103)

“…Patients with allergic rhinitis (n = 6) and healthy controls (n = 6) were enrolled, and gut microbiome composition analysis was performed by 16S rDNA sequencing. We also established an ovalbumin (OVA)-induced allergic airway inflammation murine model. …”

Responses of Nucleus Tractus Solitarius (NTS) early and late neurons to blood pressure changes in anesthetized F344 rats by Jenya Kolpakova (3909658)

“…Our findings were that: 1) Thirty-five neurons (from 46 neurons) increased firing, whereas others neurons either decreased firing upon AP elevation, or were biphasic: first decreased firing upon AP elevation and then increased firing during AP decrease. 2) Fourteen neurons with excitatory responses were activated and rapidly increased their firing during the early phase of AP increase (early neurons); whereas 21 neurons did not increase firing until the mean arterial pressure changes (ΔMAP) reached near/after the peak (late neurons). 3) The early neurons had a significantly higher firing rate than late neurons during AP elevation at a similar rate. 4) Early neuron NA-ΔMAP relationship could be well fitted and characterized by the sigmoid logistic function with the maximal gain of 29.3. 5) The increase of early NA correlated linearly with the initial heart rate (HR) reduction. 6) The late neurons did not contribute to the initial HR reduction. …”

Data_Sheet_1_Increase in presentations with new-onset psychiatric disorders in a psychiatric emergency department in Berlin, Germany during the second wave of the COVID-19 pandemic... by Maia Adam (17134579)

“…Increases in the following diagnoses were observed: new-onset of substance-related and addictive disorders (+192.5%), depressive disorders (+115.8%), schizophrenia spectrum and psychotic disorders (+113.3%) and anxiety disorders (+63.6%). …”

Image_4_Bacteroides thetaiotaomicron Ameliorates Experimental Allergic Airway Inflammation via Activation of ICOS+Tregs and Inhibition of Th2 Response.tif by Wenhui Pang (394103)

“…Patients with allergic rhinitis (n = 6) and healthy controls (n = 6) were enrolled, and gut microbiome composition analysis was performed by 16S rDNA sequencing. We also established an ovalbumin (OVA)-induced allergic airway inflammation murine model. …”

Image_2_Maternal prebiotic supplementation impacts colitis development in offspring mice.TIF by Amélie Lê (14331069)

“…However, its role in modulating the development of other intestinal disorders, such as colitis, remains unknown. Therefore, we investigated the effects of prebiotic supplementation in pregnant mice on the occurrence of colitis in their offspring.…”

Ingestion of Broccoli Sprouts Does Not Improve Endothelial Function in Humans with Hypertension by Buris Christiansen (242911)

“…<div><h3></h3><p>Ingestion of glucosinolates has previously been reported to improve endothelial function in spontaneously hypertensive rats, possibly because of an increase in NO availability in the endothelium due to an attenuation of oxidative stress; in our study we tried to see if this also would be the case in humans suffering from essential hypertension.…”

Image_2_The Indispensable Role of Histone Methyltransferase PoDot1 in Extracellular Glycoside Hydrolase Biosynthesis of Penicillium oxalicum.TIF by Yanan Li (94033)

“…<p>Histone methylation is associated with transcription regulation, but its role for glycoside hydrolase (GH) biosynthesis is still poorly understood. We identified the histone H3 lysine 79 (H3K79)-specific methyltransferase PoDot1 in Penicillium oxalicum. …”

Table_2_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…Background<p>Creatinine-cystatin C ratio (CCR) has been demonstrated as an objective marker of sarcopenia in clinical conditions but has not been evaluated as an osteoporosis marker in individuals with normal renal function.</p>Methods<p>We selected 271,831 participants with normal renal function from UK Biobank cohort. …”

DataSheet1_Efficacy and safety of fenofibrate add-on therapy in patients with primary biliary cholangitis refractory to ursodeoxycholic acid: A retrospective study and updated meta... by Xuan Guoyun (13521745)

“…Biochemical and clinical indicator changes in UDCA-refractory PBC patients receiving combination therapy were analyzed by Revman 5.42. Then, we explored the influence of fenofibrate dose and the effectiveness and safety of long-term application by retrospective cohort study.…”

Image 2_Effects of different additives on fermentation quality, mycotoxin concentrations, and microbial communities in high-moisture corn kernels during wet storage.tif by Xingya Wang (3126705)

“…LAB treatment also reduced water-soluble carbohydrate (WSC) content (5.05% DM). Microbial diversity was reduced in the LAB treatment, as evidenced by decreases in both common and unique operational taxonomic units, while the relative abundance of Weissella increased after 60 days compared to CK. …”

Chemisorption of Water on the Surface of Silicon Microparticles Measured by Dynamic Nuclear Polarization Enhanced NMR by Mallory L. Guy (3708547)

“…We use dynamic nuclear polarization (DNP)-enhanced nuclear magnetic resonance (NMR) at liquid helium temperatures to directly detect hydrogen attached to the surface of silicon microparticles. …”

Data_Sheet_1_Comparing the associations of central venous pressure and pulmonary artery pulsatility index with postoperative renal injury.PDF by Johnny Wei (13945401)

“…Objective<p>Cardiac surgery-associated acute kidney injury (CS-AKI) is associated with significant morbidity and mortality. We investigated the association of postoperative central venous pressure (CVP) and pulmonary artery pulsatility index (PAPi) with the development of CS-AKI.…”