Determination of the changes in contact area during osmotic stimulation of adhered primary hepatocytes. by Tabea A. Mundinger (124217)

“…The original relative contact area (i) changes considerably during hypoosmotic stimulation (ii) and does not return to its original area afterwards (iii). A rapid decrease in relative contact area can be observed after returning to normoosmotic media (iv) followed by the stabilization of the relative contact area (v). b) All areas defined as relative contact areas in the consensus of both wavelengths are represented here as black areas. …”

Evaluation of MGMT inhibitors with chemosensor 1. by Andrew A. Beharry (1940068)

“…<p>Incubation of purified MGMT enzyme with the inhibitors BG and PaTrin-2 led to a concentration dependent decrease in observed final fluorescence intensity, indicative of MGMT inhibition. …”

Therapeutic efficacy study in <i>E</i>. <i>granulosus</i> infected mice. by Julia A. Loos (737868)

“…<p>(A) Box plots showing the comparative distribution of the weight (g) of cysts recovered from untreated mice (C) and treated with albendazole (ABZ, 5 mg/kg/d), metformin (Met, 50 mg/kg/d) and the combination of both drugs (ABZ+Met) for 60 days. …”

Addition of 2-DG sequesters cholesterol from the cell membrane. by Charles A. Coomer (8479434)

“…<p>A.) Representative images depicting filipin mean fluorescence intensity per cell indicating two-hour incubation of increasing concentrations of 2-DG decreases surface cholesterol in TZM-bl cells; scale bar 50 μm. …”

Summary of the physiological, metabolic and hypothalamic gene expression changes in exercising Siberian hamsters with free access to a running wheel compared to sedentary Siberian... by Ines Petri (531427)

Ouabain block of the Na⁺/K⁺ pump switches Purkinje cell activity out of the trimodal firing pattern and into a continuous burst mode. by Michael D. Forrest (292801)

“…In this case, the only deflections observed are those of the Ca²⁺ spikes that have travelled into the soma from the dendritic arborisation (<i>E</i>, <i>I</i>). <i>Panel A scaling is encoded in the first scale bar (50 mV, 50 s). …”

Table 1_Time course of organ and hematological response to complement blockage in transplant-associated thrombotic microangiopathy after allogeneic hematopoietic stem cell transpla... by Tatiana A. Rudakova (20945432)

“…Secondary endpoints included the cumulative incidence of a 25% decrease in serum lactate dehydrogenase levels and to the limit of the normal range for age from the date of the initiation of eculizumab, the cumulative incidence of a 50% increase in platelet count or stable platelet levels ≥ 20×10⁹/l was 74% (95% CI, 32–92) with median time 21 days (range: 1–104), cumulative incidence of platelet level ≥ 50×10⁹/l, and 1 year from the date of the initiation of eculizumab.…”

Image_1_Biosynthesis of Silver Nanoparticles by Marine Actinobacterium Nocardiopsis dassonvillei and Exploring Their Therapeutic Potentials.jpg by Maha A. Khalil (11454121)

“…In vitro studies using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed a concentration-dependent decrease in cell viability when CaCo2 cells were exposed to Bio-AgNPs. …”

Simplified diagrammatic representation of our mathematical model. by Cyrill A. Rentsch (117042)

“…A more detailed version of this figure is provided by the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056327#pone.0056327.s001" target="_blank"><b>Figure S1</b></a> of the supplemental material.…”

Effect of PMI on cytoskeletal proteins. by Jeffrey A. Blair (3178230)

“…Scale bars = 50 μm. (B) However, by Western blot, while the proteins actin and GAPDH show no correlation with PMI times, detectable tubulin levels decrease significantly after a PMI of 22 h. …”

Table 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Table 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Table1_Alterations in circulating lipidomic profile in patients with type 2 diabetes with or without non-alcoholic fatty liver disease.docx by Assim A. Alfadda (9674998)

μCT analysis of extra-osseous extension of primary osteosarcoma. by Heather A. Cole (571670)

EWS/FLI-1 siRNA and R1507 block Ewing's sarcoma cell proliferation by inhibiting a shared pathway: phosphorylation of IGF-1R and Akt. by Helen J. Huang (201553)

DataSheet1_Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells.PDF by Jingming Niu (17268094)

“…For anticancer activity, C. oleifera bud EE had remarkable cytotoxic effect on non-small cell lung cancer A549 (IC₅₀: 57.53 ± 1.54 μg/mL) and NCI-H1299 (IC₅₀: 131.67 ± 4.32 μg/mL) cells, while showed lower cytotoxicity on non-cancerous MRC-5 (IC₅₀ > 320 μg/mL) and L929 (IC₅₀: 179.84 ± 1.08 μg/mL) cells. …”

The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2... by Da Cunha, Amanda Ramos

“…Importance: Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning. …”
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Immunofluorescence analysis of lumbar spinal cord sections at 3 months after spinal cord transection. by Jose A. Corleto (841164)

“…<b>(G, H, I)</b>- Quantitative densitometric analysis of GAD65, GFAP and IB1 immunoreactivity showed a decrease in GAD65 and increase in GFAP and IB1 staining in TSCT animals if compared to naïve controls (t-test ***-p<0.001; scale bar: A, B: 50 μm C, D, E, F: 200 μm).…”

Does the Introgression of Bt Gene Affect Physiological Cotton Response to Water Deficit? by C.A. ROSOLEM (6676022)

“…The experiment was conducted in a greenhouse, where the cotton cultivars FMT 705, FMT 709 and IMACD 8276, with and without the Bt gene, were grown under two water regimens: 100% and 50% (moderate water deficit) of available soil water. …”

Young’s Modulus and Size-Dependent Mechanical Quality Factor of Nanoelectromechanical Germanium Nanowire Resonators by Damon A. Smith (2303446)

“…Germanium cantilever nanoelectromechanical resonators were fabricated using chemically grown nanowires with diameters ranging from 50 to 140 nm. Single nanowires were mechanically positioned at the edge of a copper transmission electron microscope (TEM) grid and then pinned to the grid with local platinum deposition. …”