Data_Sheet_1_Long-term phenobarbital treatment is effective in working-age patients with epilepsy in rural Northeast China: a 10-year follow-up study.docx by Rongxin Li (3552779)

“…During the first year of treatment, 75.2% of patients experienced a ≥50% reduction in seizure frequency compared with baseline (considered as treatment effectiveness); 53.7% of patients were seizure-free. …”

Data_Sheet_1_A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model.docx by Lu-Yang Yeh (12559033)

“…</p>Results<p>50 mg/kg BW of the MPT0E028 significantly decreased the tidal volume in emphysematous mice (p < 0.05). …”

Data_Sheet_1_A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter bauman... by Sung-Pang Chen (10990884)

“…PepD3 is 3-residue shorter than pepD2. Decreasing peptide length did not affect antimicrobial activity but increased the IC₅₀ to HEK293 cells, thus increased the selectivity index (SI) between A. baumannii and HEK293 cells from 4.7 to 8.5. …”

Data_Sheet_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Pred... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Image_5_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

The Homeobox Gene <i>MEIS1</i> Is Methylated in <i>BRAF</i>^p.V600E Mutated Colon Tumors by Ashwin A. Dihal (481201)

“…The same was true for gene expression of a truncated form of <i>MEIS1</i>, <i>MEIS1</i>_<i>D27</i>, which misses exon 8 and has a proposed tumor suppression function. …”

Image_2_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_2_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Image_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_3_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_4_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

DataSheet1_Dynamic phenotypic shifts and M2 receptor downregulation in bladder smooth muscle cells induced by mirabegron.PDF by A. E. Muderrisoglu (19204042)

Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling by Sherif A. Ibrahim (504852)

“…In MCF-7 cells, Syndecan-1 depletion reduced the side population by 40% and Aldehyde dehydrogenase-1 by 50%, repectively. In MDA-MB-231 cells, the CD44(+)CD24(-/low) phenotype decreased significantly by 6% upon siRNA-mediated Syndecan-1 depletion. …”

Human vessel formation after progenitor co-transplantation depends on hypoxia-induced factors in MSPCs but not ECFCs. by Nicole A. Hofmann (138477)

“…Human mesodermal origin was visualized with anti-human vimentin monoclonal antibody staining (h.Vimentin, brown; mouse and human nuclei counterstained with hematoxylin, blue; third row; scale bar 50 µm). Plugs contain different numbers of h.Vimentin-negative infiltrating mouse CD45⁺ hematopoietic cells (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044468#pone.0044468.s006" target="_blank">Figure S6C</a>). …”

<i>NOTCH3</i> Variants and Risk of Ischemic Stroke by Owen A. Ross (139522)

“…</p> <p>Results</p><p>Sequencing of the 269 SWISS probands identified one (0.4%) with small vessel type stroke carrying a known CADASIL mutation (p.R558C; Exon 11). Of the 19 common <i>NOTCH3</i> variants identified, the only variant significantly associated with ischemic stroke after multiple testing adjustment was p.R1560P (rs78501403; Exon 25) in the combined SWISS and ISGS Caucasian series (Odds Ratio [OR] 0.50, P=0.0022) where presence of the minor allele was protective against ischemic stroke. …”

Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection. by Olga A. Maximova (3115716)

“…Note: (i) pial lymphocytic infiltration (yellow arrows) appeared at 7 dpi (<b>G</b>), increased at 14 dpi (<b>H</b>), and decreased at 21 dpi (returning to the level seen at 7 dpi) (<b>I</b>); (ii) a rare focal lesion (red asterisk in H) with depleted MAP2-IR in the Purkinje cell layer (PCL), granule cell layer (GrCL) neurons, and partially in the molecular layer (ML) is spatially associated with the increased pial lymphocytic infiltration. …”

Simplified depiction of hyperthermia impacts on the intrafollicular complement and coagulation cascade. by Louisa A. Rispoli (8201232)

“…Alpha-2-Macroglobulin (A2M) is an anti-proteinase that complexes with proteinases such as kallikrein [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0227095#pone.0227095.ref050" target="_blank">50</a>] to inhibit proteolytic activity.…”

Data_Sheet_1_Assessing the Impact of Ih Conductance on Cross-Frequency Coupling in Model Pyramidal Neurons.docx by Melvin A. Felton (9358796)

Table_1_COVID-19 Era Effect on Pandemic and Post-pandemic Pediatric Telemedicine Use: A Survey of the European Academy of Pediatrics Research in Ambulatory Settings Network.XLSX by Stephen M. Reingold (11596360)

“…Little is known about what we can expect after the pandemic: if physicians will opt for telemedicine modalities and if tele-pediatrics will continue to be a significant mode of community pediatric care.…”