Increased Autophagy in <i>daf-2/</i>insulin/IGF Receptor Mutants Is Independent of the <i>daf-16</i>/FOXO and <i>pha-4</i>/FOXA Transcription Factors by Malene Hansen (10367)

“…The mean lifespan of <i>daf-2(e1370)</i> animals was shortened 12.5% by <i>pha-4</i> RNAi ([<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040024#pgen-0040024-b028" target="_blank">28</a>] and data not shown), and we measured an 11% decrease in puncta in <i>daf-2(e1370)</i> animals fed <i>pha-4</i> RNAi. …”

Requirement of viral DNA replication for sT-mediated late gene reporter activation in MCV reporter viral genomes. by Kyle Rapchak (13833941)

“…<b>(B)</b> Quantification of late gene-driven ZsG positive cells (top panel) and mean fluorescence intensity (bottom panel). Cells obtained from 6 independent transfections were analyzed by flow cytometry. sT deletion does not significantly decrease ZsG positive cells whereas introducing a mutation into the NCCR (MCVΔsT.L-ZsG_rep-) decreased percent positivity by 50%. …”

Datasheet1_Outcomes among patients undergoing transcatheter aortic valve replacement with very low baseline gradients.docx by Faisal Rahman (11048519)

“…Background<p>While there is evidence that patients with low-flow, low-gradient aortic stenosis (AS) benefit from transcatheter aortic valve replacement (TAVR), data are lacking regarding outcomes of patients with a very low gradient (VLG).</p>Methods<p>In this retrospective, single-center study of patients with severe AS who underwent TAVR, three groups were defined using baseline mean aortic valve gradient: VLG (≤25 mmHg), low gradient (LG, 26–39 mmHg), and high gradient (HG, ≥40 mmHg). …”

Period of latency, progression and duration of blockade of epidural anesthesia with lidocaine, bupivacaine or its association in dogs by S.J. Ronchi (8143470)

Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

ENMD-1198 inhibits c-Src-mediated STAT3 activation. by Saad Yousuf (541082)

“…A decrease in transcriptional activity was observed in cells **(p<0.00004) transfected with RKIP and treated with IL-6 when compared to cells treated with IL-6 (<i>bars</i>  =  mean ± S.D., of 2 experiments performed in triplicate). …”

Suppressing amphiregulin expression in tumor-supportive fibroblasts reduces tumorigenicity and amount of mesenchymal cells. by Megha Rajaram (424995)

“…Error bars represent SEM. There was a small decrease in proliferation in the shAREG-2 HFFF2 fibroblast group (not statistical significance, p = 0.06). …”

Efficacy and selectivity of the shSNP <i>in vitro</i>. by Valérie Drouet (3179907)

“…Newman-Keuls Post-hoc comparison between the shCtrl groups and shSNP groups indicated significant efficacy for sh39A, sh39C, sh50T, sh67T, sh67C (***P<0.001), sh60G (**P<0.01) and sh60A (*P<0.05) whereas the difference between the control condition and the sh50C condition was not statistically significant. …”

SINGLE PORT LAPAROSCOPIC CHOLECYSTECTOMY: TECHNICAL ASPECTS AND RESULTS by Murillo de Lima FAVARO (5670416)

“…Conversion to open surgery occurred in three cases (1.76%). The mean surgical time was 67.97 min, showing a marked decrease when was reached close to 50 cases and a stabilization after 100 surgeries. …”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…<p>(A–C). 50,000 cells from SUM159 cell line or two breast cancer xenografts, MCI, or UM2 were injected into NOD/SCID mice and the tumor size was monitored. …”

SOCS-1 silencing enhances cytokine production and stimulatory capacity of mo-DCs. by Meenakshi Sachdeva (817136)

“…Friedmann test was performed for comparisons between treated groups with pairwise comparisons using Dunn's multiple comparison adjustment for an overall p values <0.05. (a) Mo-DCs treated with siSOCS-1 had around 50% decrease in the expression of SOCS-1 gene which was significantly less than the control cells (p<0.05). …”

Image_1_Innovative agroecological practices can restore degraded farmlands and revive crop yields.JPEG by Jules Ntamwira (9683561)

“…T3 (compared to T1), had a decrease in acidity and Al³⁺; an increase in soil organic matter, K+, Ca+, and aboveground carbon stock (26.5 t/ha against 5.6 t/ha). …”

Comprised dendritic arbors in ephrinB1 mutant cortical pyramidal cells. by Dina N. Arvanitis (521401)

“…</i> Sholl analysis of the structure of dendritic arbors. Mean number of dendritic intersections of layer II/III cortical pyramidal neurons show a significant decrease in the number of intersections in pyramidal neurons from <i>EfnB1^Y/−</i> cortex at longer distances from the cell soma. …”

EWS/FLI-1 and R1507 influence the activation/expression of key molecules in the IGF-1 signaling pathway. by Helen J. Huang (201553)

“…Anti-GAPDH was used as a loading control. Experiments were performed in the presence or absence of 50 µg/ml rIGF-1. …”

Characterizing Interface Shape Evolution in Immiscible Polymer Blends via 3D Image Analysis by Carlos R. Lopez-Barron (2355784)

“…Distributions of the curvatures at different annealing times were obtained by measuring <i>H</i> and <i>K</i> at many (typically 10⁷) points on the interface. Coarsening of a symmetric (50/50 w/w FLPS/SAN) and a nonsymmetric (35/65 w/w) blend was monitored. …”

Characterizing Interface Shape Evolution in Immiscible Polymer Blends via 3D Image Analysis by Carlos R. Lopez-Barron (2355784)

“…Distributions of the curvatures at different annealing times were obtained by measuring <i>H</i> and <i>K</i> at many (typically 10⁷) points on the interface. Coarsening of a symmetric (50/50 w/w FLPS/SAN) and a nonsymmetric (35/65 w/w) blend was monitored. …”

Improvement of the French voicing categorical perception in children with SLI after phonological auditory training by Gregory Collet (7422254)

“…During each session, ten blocks of 20 stimuli (10 pairs with the same two stimuli and 10 pairs with two different stimuli) were</div><div>presented to the children in a random order. The first blocks were built using stimuli separated by an important acoustical distance: 50 ms (-25 vs +25 msec de VOT). …”

Data_Sheet_1_Coastal Flooding in the Balearic Islands During the Twenty-First Century Caused by Sea-Level Rise and Extreme Events.zip by Pau Luque (11248140)

“…<p>Sea-level rise induces a permanent loss of land with widespread ecological and economic impacts, most evident in urban and densely populated areas. …”

Cell viability in monolayer and 3D aggregate cultures after oxidative stress induced by H₂O₂. by Mireille M. J. P. E. Sthijns (12245491)

“…<p>The percentage of viable cells is shown relative to the control that was not exposed to H₂O₂. A) In monolayer culture, the higher the percentage of INS1E cells included in the co-culture, the more H₂O₂ was necessary to induce a similar decrease in viability. …”

Exogenous TGF-β delays mortality in HK/483-infected mice. by Christina M. Carlson (240307)

“…Error bars represent standard error of the mean. Asterisk (*) indicates significant increase in TGF-β levels as compared with other groups (A); difference in weight loss (B) or mortality (C) as compared with HK/483 virus and AdDL70-treated mice; and decrease in viral titers as compared with HK/483 infected mice (D).…”