LPC-DHA inhibits Srebp activity and de novo lipogenesis and Mfsd2a is regulated by Srebp. by Jia Pei Chan (5593388)

“…<p>(A) Western blot analysis of Scd1 and Mfsd2a expression in NSC^WT and NSC^KO treated with or without 50μM LPC-DHA. …”

Preliminary dose-response experiments. by Noelia Torremadé (3687523)

Membrane-localized AR facilitates productive endocytosis and nuclear trafficking of KSHV. by Xing Wang (154377)

“…Cells were performed as mentioned above, except lacking of Triton X-100 treatment in non-permeabilized group. Scale bars represent 50 μm. (c) Knockdown of AR and EphA2 expression reduces KSHV endocytosis, as indicated by decreasing gB staining in cells. …”

Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…We added their proxy variants in LD (r² ≥ 0.8; based on 1000 genomes project data [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref050" target="_blank">50</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref051" target="_blank">51</a>]). …”

Video_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.mov by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Presentation_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.pdf by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Table_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.XLS by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Simulated average monthly flow at the 10 outflow assessment nodes in the five river basins over the 2008 to 2020 period (HMRB: Harirod-Murghab River Basin, HRB: Helmand River Basin... by Fazlul Karim (7225826)

SEM images of lattice scaffolds; A) 4 layers, B) 6 layers, C) 8 layers, D) 10 layers, and staggered scaffolds; E) 4 layers, F) 6 layers, G) 8 layers, H) 10 layers. by Zahra Yazdanpanah (10038944)

Position of committed effective dose <i>E</i>_U+LS between <i>E</i>_LS and <i>E</i>_U (Bq d^–1). by Martin Šefl (11607984)

A complete set of mathematical model equations utilized in ILYCM software to develop S. <i>frugiperda</i> phenology for each life stage. by Marian Adan (16641634)

Fig 2 - by Muhammad Imran Nisar (10226212)

Individual serotype carriage rates over the study period. by Muhammad Imran Nisar (10226212)

The carriage rate of VT serotypes by number of doses of vaccine. by Muhammad Imran Nisar (10226212)

Serotype specific carriage rate from 2014–18 in Matiari, Pakistan. by Muhammad Imran Nisar (10226212)

Serotype-specific carriage rate by vaccination status. by Muhammad Imran Nisar (10226212)

Pre-diabetes is associated with increased risk of heart failure among patients with atrial fibrillation by Jia-Yi Huang (12733928)

“…Compared to those who remained pre-diabetic, patients who progressed to diabetes were associated with an increased risk of HF (SHR=1.50, 95% CI: 1.13-1.97), whereas those who reversed to normoglycaemia were associated with decreased risk (SHR=0.61, 95% CI: 0.42-0.94). …”