Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…Two diffusing populations were also measured for the chemically different probes ATTO 647N, DiD, and Nile Blue chloride in [P₆₆₆₁₄][Cl] at 20 °C. In contrast, only a single fast population was measured in [P₆₆₆₁₄][Cl] at 50 °C. …”

PRL decreases anterior pituitary cell proliferation <i>in vivo</i>. by Jimena Ferraris (314722)

Time kill kinetics of WSWE against <i>S</i>. <i>globosa</i>. by Acharya Balkrishna (5640038)

Plasma membrane localized KCa3.1 is decreased by DN Rab1 and Rab8, but not by Rab2 or Rab6. by Claudia A. Bertuccio (309866)

Iminosugar-based GCS inhibitors decrease brain GFAP positive cells. by Karen M. Ashe (349018)

Iminosugar-based GCS inhibitors decrease brain α-synuclein aggregates. by Karen M. Ashe (349018)

3‑Hydroxyquinolin-2-Ones Act as Dual Inhibitors of Ferroptosis and Monoamine Oxidase B: Reducing Alzheimer’s Disease-Related Amyloid Precursor Protein and Hyperphosphorylated Tau I... by Yangjing Lv (21580685)

“…Compound <b>21d</b> emerged as a promising candidate, exhibiting potent and selective MAO-B inhibitory activity (IC₅₀ = 87.47 nM, SI > 229), as well as excellent antiferroptosis activity through modulation of the iron metabolic pathway and GSH-GPX4 axis in vitro<i>.…”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Here, by addressing a high-energy water, we improved the IC₅₀ value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Here, by addressing a high-energy water, we improved the IC₅₀ value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…<p>^a SNP with the strongest association to targeted metabolic traits (“lead SNP”)</p><p>^b SNP with the strongest association to non-targeted metabolic traits</p><p>^c manually added to the list of most plausible candidate genes derived by evidence-based selection</p><p>^d additional candidates match to other non-targeted traits that also associate with the lead SNP</p><p>^e results from GWAS (<i>P</i> < 5.0×10⁻⁸)</p><p>^f mutations determined in clinical studies</p><p>For each locus, we selected all variants that displayed genome-wide significant association signals to metabolic traits in the SHIP-0 cohort. …”

Absolute values at control recording (Protocol 1). by Yoichiro Kitajima (4319455)

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Effect of atipamezole or efaroxan (1 mg·kg⁻¹) (Protocol 2). by Yoichiro Kitajima (4319455)

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Effect of atipamezole or efaroxan (0.5 mg·kg⁻¹) (Protocol 2). by Yoichiro Kitajima (4319455)

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Maps of median projected λ_<i>S</i> (a) and <i>R</i>₀ (b) across 1st-level sub-national administrative regions in selected South American countries. by Keith Fraser (1868587)

Evaluation of the Acid Baking Technique to Decrease the Phosphorus Content of the Iron Ore by Leonardo Martins da Silva (7425692)

Decrease in the number of prescriptions for antibiotics in percentage, by studies assessing this outcome parameter. by Christin Löffler (3539528)

Visual deprivation rescues the decrease in proliferative cells by HDAC1 knockdown. by Yi Tao (178829)

Area of cumulus oocyte complexes (COCs; μm²) at 0, 6, 12 and 19 h of the maturation period. by Verónica M. Negrón-Pérez (20691412)

Portfolios with different number of securities involved in E(r) – risk system. by Mihály Ormos (697939)

Postnatal decrease in PV+ cortical interneurons in Fgfr1 mutant mice. by Karen Müller Smith (613941)

“…Scale bar is 50 µm in <b>A</b>,<b>B</b>. Stereological analysis show significant decreases in in both GFP and PV immunopositive cells in Fgfr1 mutant mice as compared to littermate controls (<b>C</b>). …”