Search alternatives:
greater decrease » greater increase (Expand Search), greater increases (Expand Search), rate decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
greater decrease » greater increase (Expand Search), greater increases (Expand Search), rate decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1.
Published 2014“…Scale bar, 2 microns. Data shown are mean values ± SD, <i>p</i><0.01. (C) Hippocampal neurons were labeled using anti-vGLUT1 and anti-vGAT antibodies, followed by Alex Fluor 488 or 568 labeled secondary antibodies, respectively. …”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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GluN2A(D731N) decreases channel open probability.
Published 2017“…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”
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TMD residues decrease sensitivity.
Published 2017“…Glu residues are color coded based upon effect, with residues in red producing a significant decrease in pH<sub>50</sub>, and in yellow, an insignificant or weak effect, whereas the dark purple and magenta for His residues are synonymous to the red of Glu residues. …”