image1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.tif by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

Data_Sheet_1_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…We found: (1) The vast majority of MG miRNAs declined in reactive MG 7 days after light damage. (2) Only four miRNAs increased after light damage, which included miR-124. (3) The top 10 genes found upregulated in reactive MG after light damage include Gfap, Serpina3n, Ednrb and Cxcl10. (4) The miRNA decrease in reactive MG 7 days after injury resembles the profile of Dicer-depleted MG after one month. (5) The comparison of both mRNA expression datasets (light damage and Dicer-cKO) showed 1,502 genes were expressed under both conditions, with Maff , Egr2, Gadd45b, and Atf3 as top upregulated candidates. (6) The DIANA-TarBase v.8 miRNA:RNA interaction tool showed that three miRNAs were found to be present in all networks, i.e., after light damage, and in the combined data set; these were miR-125b-5p, let-7b and let-7c. …”

Data_Sheet_2_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…We found: (1) The vast majority of MG miRNAs declined in reactive MG 7 days after light damage. (2) Only four miRNAs increased after light damage, which included miR-124. (3) The top 10 genes found upregulated in reactive MG after light damage include Gfap, Serpina3n, Ednrb and Cxcl10. (4) The miRNA decrease in reactive MG 7 days after injury resembles the profile of Dicer-depleted MG after one month. (5) The comparison of both mRNA expression datasets (light damage and Dicer-cKO) showed 1,502 genes were expressed under both conditions, with Maff , Egr2, Gadd45b, and Atf3 as top upregulated candidates. (6) The DIANA-TarBase v.8 miRNA:RNA interaction tool showed that three miRNAs were found to be present in all networks, i.e., after light damage, and in the combined data set; these were miR-125b-5p, let-7b and let-7c. …”

Anteriorly traveling Lfng stripes and segmentation-clock period. by Susan D. Hester (204004)

“…We increase or decrease the segmentation-clock period by varying how long we integrate the segmentation-clock ODEs during each time step; by doing so, we easily vary the clock period relative to other processes in the simulation without altering parameters within the segmentation-clock submodel or changing the clock response to FGF8, Wnt3a or Delta/Notch signaling. …”

image1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.tif by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

Osteogenic and microstructural characterization in normal versus deformed jaws of rainbow trout (Oncorhynchus mykiss) from freshwater by Cristian Sandoval (12543595)

“…Methods. We included five normal fish and five specimens with mandibular deformation in smolt rainbow trout weighing 400 g and measuring 25 to 35 cm in length. …”

Data_Sheet_1_Soil Application of Almond Residue Biomass Following Black Soldier Fly Larvae Cultivation.docx by Robert Axelrod (6307505)

“…Sandy loam (SL) and sandy clay loam (CL) soils amended with BSFL-digested almond processing residues, i.e., spent pollinator hulls (SPH), at 2% dry weight (dw) were incubated under aerobic and anaerobic conditions for 15 days under a daily fluctuating temperature-interval (30–50°C). …”

Changes in EPSC parameters have little effect on the ISI distribution. by Trystan Leng (4229680)

“…(<b>A)</b> Increasing the EPSC magnitude (Δ_epsc) slightly increases the number of short ISIs, shifting the distribution to the left, with a small decrease in the height of the mode. Plotted distributions are for EPSP magnitudes of ~ 1, 2, 3, and 4 mV (darkest to lightest). …”

Diet Modification and Metformin Have a Beneficial Effect in a Fly Model of Obesity and Mucormycosis by Fazal Shirazi (413427)

“…Survival was significantly decreased (<i>P</i> = 0.003) in obese flies, while post-infection glucose levels were significantly increased (<i>P</i> = 0.0001), compared to normal-weight flies. …”

Additional <i>Setd5</i> behavioural controls. by Laura E. Burnett (18794525)

“…<b>(A</b>) Average speed during prestimulus exploration (<i>Setd5</i>^+/+, 7.50 cm s⁻¹; <i>Setd5</i>^+/−, 6.65 cm s⁻¹, <i>P</i> = 0.151). …”

greenhouse experiment analysis script by Brittany Cavazos (17226175)

Axon misguidance phenotypes in vivo occur where the Shh gradient is shallow. by Tyler F. W. Sloan (715369)

“…<p><b>(A)</b> Mouse e9.5 (left) and e10.5 (middle and right) spinal cord cross-sections immunostained for Shh. …”

Dual effects of propofol on C2C12 cells. by Xi Chen (35903)

“…<p>(A) Exposure for 48 h to 25, 50, 100, 150, and 250 μM propofol significantly increased cell count relative to that of the control in a concentration-dependent manner. …”

Electrical characteristics and density of states of thin-film transistors based on sol-gel derived ZnO channel layers with different annealing temperatures by Wang S.

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Are Standard Follow-Up Parameters Sufficient to Protect Neurocognitive Functions in Patients with Diabetes Mellitus who Underwent Coronary Artery Bypass Grafting? by Hakan Sacli (8618775)

Supplementary Material for: Forecasting the Worldwide Impact of Stroke for individuals aged 45 and above by Fan W. (11417327)

Supplemental Figs. S1-S7 by Carolyn Morris (21298187)

Cephalometric changes during aging in subjects with normal occlusion by Daniela GARIB (12682165)

Effect of remediation technologies on soil fertility in heavy metal(loid)-contaminated soils: A critical review by Lizhi He (6734888)

datasheet1_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.pdf by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”