Presentation_1_Dietary Oxalate Loading Impacts Monocyte Metabolism and Inflammatory Signaling in Humans.pptx by Parveen Kumar (428921)

“…Increased consumption of meals with high oxalate content may stimulate urinary calcium oxalate (CaOx) crystals, which are precursors to CaOx kidney stones. We previously reported that CaOx stone formers have decreased monocyte cellular bioenergetics compared to healthy participants and oxalate reduces monocyte metabolism and redox status in vitro. …”

DataSheet_1_Evaluation of a Colombian oregano oil (Lippia origanoides Kunth) and a novel yeast product from Pichia guilliermondii, alone or in combination, on rumen fermentation, m... by Eva Ramos-Morales (4370035)

“…Whereas essential oils act through selective inhibition of microbial groups, yeasts are thought to work through the selective stimulation of key microbes in the rumen. We hypothesized that yeast supplementation could modulate the antimicrobial effect of a high thymol-containing oregano oil, allowing a more efficient feed utilization whilst decreasing methane production. …”

Image 2_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Crowders-Induced Compaction of Multi-kbp Long DNA Molecules Followed by TPM by Manoel Manghi (1588447)

Image 2_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

DataSheet_1_Natural variation of RGN1a regulates grain number per panicle in japonica rice.pdf by Quan Zhang (168081)

“…The RGN1a mutation caused 37.2%, 27.8%, 51.2%, and 25.5% decreases in grain number, primary branch number per panicle, secondary branch number per panicle, and panicle length, respectively. …”

Table 2_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Table 3_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Image_1_Effects of Soil Physico-Chemical Properties on Plant Species Diversity Along an Elevation Gradient Over Alpine Grassland on the Qinghai-Tibetan Plateau, China.pdf by Wangya Han (12044681)

“…Alpine grassland on the QTP has suffered from a serious decline in plant species diversity. In this study, we investigated 112 sites recording plant community characteristics and collecting soil samples along an elevation gradient (3,500–5,200 m asl) in alpine meadow on the QTP. …”

Video_6_Minimizing Guidewire Unwilling Passage and Related Perforation During Transradial Procedures: Prevention Is Better Than Cure.WMV by Lili Xu (257856)

“…Afterwards we included 239 patients and randomized them according to a random number table to either the unmodified or the knuckle guidewire to further confirm the efficiency and safety of knuckle guidewire advancement.…”

DataSheet1_Guhong Injection Alleviates Cerebral Ischemia–Reperfusion Injury via the PKC/HIF-1α Pathway in Rats.docx by Li Yu (81651)

“…After establishing an MCAO rat model, we performed neurological deficit testing, 2,3,5-triphenyltetrazolium chloride staining, hematoxylin and eosin (HE) staining, enzyme-linked immunosorbent assay, Western blotting, and q-PCR to detect the brain damage in rats. …”

Table_1_The Legacy of Hurricanes, Historic Land Cover, and Municipal Ordinances on Urban Tree Canopy in Florida (United States).DOCX by Allyson B. Salisbury (12083516)

“…As peak gust speeds increased from 152 km/h (i.e., a lower-intensity Category 1 storm) to 225 km/h (lower-intensity Category 4 and the maximum gusts captured in our data), predicted canopy in developed urban areas decreased by 7.7%. Beyond the impacts of hurricanes and tropical storms, we found that historic landcover and two out of eight urban forest ordinances were significant predictors of existing canopy coverage (P-landcover < 0.001; P-tree preservation ordinance = 0.02, P-heritage tree ordinance = 0.03). …”

Improving Degradation Efficiency of Organic Pollutants through a Self-Powered Alternating Current Electrocoagulation System by Linglin Zhou (1626217)

“…Moreover, the removal efficiency can be further enhanced by decreasing the frequency AC, in which a 5.7-fold improvement was achieved at 0.2 Hz compared to DC at 1.8 Hz. …”

Table_2_Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation.docx by Sang Wha Kim (5600183)

“…The experiment was conducted on two shark species—Triakis scyllium and Triaenodon obesus. We found that intramuscular injections of 0.2 mL/kg of Ovaprim^® for male T. scyllium and T. obesus, 0.2 mL/kg + 0.5 mL/kg at a 24 h interval for female T. scyllium, and 0.2 mL/kg + 0.2 mL/kg or 0.2 mL/kg + 0.3 mL/kg at a 24 h interval for female T. obesus were optimal dose protocols. …”

Association between albumin infusion and sepsis. by Xuan Zhou (329338)

“…Subgroup analysis showed a negative association between the albumin infusion and sepsis risk in the AP patients with serum albumin ≤ 3.5g/L (adjusted OR=0.29, 95%CI = 0.08–0.77).</p><p>Conclusion</p><p>In this study, we found an association between albumin administration and a lower risk of sepsis in AP patients, which persisted after multivariate adjustment. …”

Data_Sheet_1_LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes.PDF by Yahya Sohrabi (160108)

“…Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X Receptor (LXR), a key regulator of cholesterol and fatty acid homeostasis, in trained innate immunity.…”

DataSheet9_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.docx by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

Image_1_Causal association of sarcopenia with hepatocellular carcinoma risk in European population: a Mendelian randomization study.pdf by Jiali Cao (5182079)

“…However, we found no evidence supporting a causality between WP and HCC. …”

Covalent <i>Plasmodium falciparum</i>-selective proteasome inhibitors exhibit a low propensity for generating resistance <i>in vitro</i> and synergize with multiple antimalarial ag... by Barbara H. Stokes (5697422)

“…Selection studies reveal that parasites do not readily acquire resistance to WLL or WLW and that mutations in the β2, β5 or β6 subunits of the 20S proteasome core particle or in components of the 19S proteasome regulatory particle yield only Plasmodium proteasome that can select for resistant parasites with >hundred-fold decreases in susceptibility. …”

Table3_Comprehensive Analysis of the Transcriptome-Wide m6A Methylation Modification Difference in Liver Fibrosis Mice by High-Throughput m6A Sequencing.DOCX by Chang Fan (5305073)

“…In an additional cell experiment, we also observed that the decreased expression of WTAP induced the development of LF as a result of promoting hepatic stellate cell (HSC) activation. …”