Contemporary mean inundation fraction in the Amazon basin. by Nic Gedney (19762301)

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. by Mamoru Miyasaka (9187916)

Cumulative distribution of EQ-5D-3L utilities decreasingly ordered before and after the onset of cutaneous leishmaniasis symptoms. by Janaína de Pina Carvalho (12152812)

Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species by Peter A. Sidhom (14313061)

“…Also, compound <b>8b</b> decreased blood glucose by α-glucosidase inhibition (IC₅₀ = 4.48 ± 0.32 μM), compared to acarbose (7.40 ± 0.41 μM), based selectively on the plasma window of <b>8b</b>. …”

The decrease in blood flow disrupts CV pruning. by Lin Wen (557398)

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

The effect of MSC blocker GsMTx-4 on photoresponses from <i>Xenopus</i> rods. by Ulisse Bocchero (9128127)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

“…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …”

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Geniposide(Gen) significantly decreased the levels of TNF-α and MIP-1α in BALF of bleomycin-induced PF mice. by Jian-Bin Yin (19556105)

Recommendations of no-fly zones for the colonies of common terns, Sandwich terns, black headed gulls, herring gulls and lesser black-backed gulls, great cormorants and Eurasian spo... by Estefania Velilla (22566709)

TBC-2 is required for full lifespan extension and increased fat storage resulting from decreased insulin/IGF signaling. by İçten Meraş (13184380)

Data_Sheet_1_Switching to second line MS disease-modifying therapies is associated with decreased relapse rate.PDF by James John Marriott (16935942)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…<i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Capsaicin, pyridoxine, vincristine sulfate and ionomycin significantly decreased axon length ratio but only pyridoxine had no impact on neurotoxicity. by Fei San Lee (17282886)

“…At a lower dose, 50 μM Pyr, did not induce significant change in axon length ratio over time and between PBS control in both female and male rat DRGs. …”

Least squares mean (LSM) + standard error (SE) of C3 concentration, ACH50 and CH50 values in different haplotypic combinations among 354 Chinese Holstein cows. by Yonghui Wang (287491)