Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by Sneha P. (3926957)

“…Triplicate runs of molecular dynamic (MD) simulations (50ns) revealed smaller changes in patterns of deviation, fluctuation, and compactness, in complexes containing the R131Q and R131W mutations, compared to complexes containing the R203C mutant complex. …”

Cardiac-specific p38γ/δ^act overexpression decreases cardiac glycogen storage and lipid accumulation. by Ayelén M. Santamans (5487941)

VANGL2 recruits NLRP3 to OPTN for selective autophagic degradation. by Huaji Jiang (16907514)

Lys823 in NLRP3 is essential for its K27-linked ubiquitination and autophagic degradation. by Huaji Jiang (16907514)

SPC decreases cardiac infarct size, increases LV contractile function and attenuates histopathologic organ damage following I/R. by Peng Yu (48605)

PPARα expression was decreased in aged and photoaged human skin and in UV-irradiated skin <i>in vivo</i> and in dermal fibroblasts. by Mi Hee Shin (406400)

VANGL2 recruits MARCH8 to promote the K27-linked ubiquitination of NLRP3. by Huaji Jiang (16907514)

Thyromental height test as a new method for prediction of difficult intubation with double lumen tube by Piotr Palczynski (5745908)

“…The optimal sensitivity and specificity values of thyromental height test were met with a cut off value of 50 mm. With 1 mm increase in thyromental height test, risk of difficult intubation decreased by 7%.…”

Deletion of GIRK2, but not GIRK1, leads to increased Fos expression by the arcuate AgRP neurons. by Youjin Oh (3308670)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Normalized importance values (Mean Decrease Gini of Random Forest) of different category-wise features. by Md. Khaledur Rahman (4326274)

Validation of AgRP neuron-specific <i>Girk1</i> and <i>Girk2</i> deletion. by Youjin Oh (3308670)

Effect of PI3K/mTORC1/2, AKT and mTORC1 inhibition on heat stress AKT signaling and clonogenic survival in HCC cells. by Scott M. Thompson (231230)

Fourteen days after tMCAo surgery mice with RNS60 treatment show a decrease in microglial activation Iba1 (+) in the CA3 region of the ipsilateral hippocampus. by Gloria Patricia Baena-Caldas (17721328)

<i>In vitro</i> 95% CI lower and upper mean susceptibility responses of field isolates to antimalarials. by Winnie Okore (14139712)

A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans by Seongwon Cha (107939)

“…<div><p>The thoracic-to-hip circumference ratio (THR) is an anthropometric marker recently described as a predictor of type 2 diabetes. In this study, we performed a genome-wide association study (GWAS) followed by confirmatory analyses to identify genetic markers associated with THR. …”

(a) Tuberculosis (TB) incidence rate of 90 countries in 1990 and (b) TB mortality rate of 28 countries in 1950, according to the BCG vaccination status in 2015. by Kazuo Inoue (302545)

Life expectancy (<i>e</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

Life expectancy (<i>e</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

An increased daytime sleep and decreased nighttime sleep can be caused by decreasing the expression of <i>dbt</i> with <i>dbt</i>-GAL4, which is expressed broadly in the optic lobe... by Jialin Wang (490082)