Nbs1 foci formation and Nbs1 expression is Myc dependent. by Lina Guerra (85942)

“…Each bar represents the mean of three independent experiments ± SD; * statistically significant decrease in Nbs1 foci formation. A cell with more than 5 nuclear foci was scored as positive. …”

Gene transcription profiling of the host response to <i>B. abortus</i> strains at 4 hours after infection of bovine trophoblastic cells. by Juliana P. S. Mol (635370)

“…<p>(A) A heat map of gene transcription changes in bovine trophoblastic cells infected with wild type, Δ<i>virB2</i> and Δ<i>btpB B. abortus</i>– strains, compared to mock-infected controls. …”

Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus. by Md Rezaul Islam (19649494)

“…Merged panel shows all three markers. 20x objective. Scale bar = 50 pixels. Bar plots show the mean proportion of <i>Reln</i>+ neurons between the ambient and stimulation groups. …”

Turbocharging Matched Molecular Pair Analysis: Optimizing the Identification and Analysis of Pairs by Iva Lukac (593803)

Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer by Kyle R. Cron (455028)

“…Proteasome inhibition resulted in an 80–90% decrease in homologous recombination (HR), a 50% decrease in expression of NF-κB-inducible HR genes <i>BRCA1</i> and <i>FANCD2</i>, and a reduction of BRCA1, FANCD2 and RAD51 ionizing radiation-induced foci. …”

Y-27632 treatment of P19 cells inhibits the differentiation of primitive endoderm. by Roman J. Krawetz (309735)

“…FACS analysis demonstrates a significant decrease in GATA-6 and Troma-1 positive cells with Y-27632 present (K). …”

Menthol and eugenol as natural anesthetics for early juveniles of curimba by Elias Fernandes de Medeiros Junior (4832202)

“…Increased concentrations led to a decrease in recuperation time. The concentrations between 50 to 70 mg of eugenol L−1 provided the lowest induction times; however, recovery time was not affected by eugenol concentrations. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

Ror2 regulation of MMP2 expression in RCC cells is dependent upon an intact kinase domain. by Neal R. Rasmussen (679331)

“…<p>Quantitative RT-PCR for 786-0 cells shows a significant correlated decrease in <b>A</b>) Ror2 and <b>B</b>) MMP2 mRNA levels in both shRNA knockdown cell lines relative to control. …”

In vitro and in vivo effects of bromodomain inhibition by JQ1 treatment. by Ryan Draker (121524)

“…JQ1 treatment does not reduce total levels of Brd2, AR or H2A.Z although a small decrease in total levels of H4Ac are observed (see main text). …”

Effects of endogenous prostanoids and selective agonists on the beating rate of neonatal rat cardiomyocytes. by Hakima Mechiche (308181)

“…“bradyarrhythmia” indicated a decrease of more than 50%; “tachyarrhythmia” indicated an increase of more than 50% with chaotic, asynchronous, activity of the myocytes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045273#pone.0045273-Li1" target="_blank">[13]</a>; <i>n</i> is the number of preparations on which brady- or tachy-arrhythmia was observed.…”

The interactive influence of T2D on Bifidobacterium genus in men using or not using opioids. by Elena Barengolts (4734798)

“…CPM = count per million, DM = type 2 diabetes, Substance = opioids. (A) 2.3 log2 fold decrease in subjects with vs. without T2D when both groups are not using opioids (q = 0.03). …”

Transcripts reduced by FRLFE in rat hepatocytes. by Ryota Yamanishi (547533)

“…<p>*The fold-change in signal ratios observed by microarray analysis of the mRNA levels at 2.5 h is indicated.…”

Upregulation of the arginase pathway in tumor infiltrating microglia (MG) and macrophages (MP). by Ian Zhang (2168401)

“…<p><b>A)</b> Heat map showing clustering of genes involved in the arginase pathway. …”

Monoclonal antibody binding to gp140_SF162 in the presence of adjuvant. by Rachel P. J. Lai (172124)

“…The data is color coded: Yellow represents no difference in mAb binding, or no change of antigenicity as compared to the unadjuvanted sample and light blue represents up to 3-fold decrease of mAb binding (or antigenicity). Both FIA and MF59 adjuvants appeared to have little effect on antigenicity, as mAb binding was very similar to the unadjuvanted sample. …”

Enrichment in genes with concordant responses vs. non-concordant responses between the survival profiling and transcriptome profiling experiments. by Alexandra Ketcham (492291)

“…<p>Genes that decrease survival when disrupted (with survival scores below -0.5) and are upregulated in the resistant strain (with log₂ fold change TPM over 0.5) were enriched in all four RNA seq expression comparisons: (A) shows survival scores with the expression of resistant (evolved) starved vs sensitive (parental) starved; (B) shows survival scores with the expression of resistant (evolved) vs sensitive (parental) unstarved; (C) shows survival scores with the expression of resistant (evolved) starved vs resistant (evolved) unstarved; and (D) shows survival scores with the expression of sensitive (parental) starved vs sensitive (parental) unstarved.…”

Network of the downregulated proteins present in _sEVs-IC and the miRs from WL-IC that might regulate them. by María-Angélica Calderón-Peláez (2851865)

“…Oval’s background green color indicates the decrease in protein regulation (FC: fold-change), and the edge color of the oval shapes represents the biological process associated with the respective proteins. miRs (blue) are part of a regulation network showed with black arrows.…”

Differential regulation of Bcl-2 in NRP1-deficient and control keratinocytes following UVB irradiation. by Anna Riese (294974)

“…Prior to UVB treatment the amounts of Bcl-2 are comparable between control and NRP1-deficient samples (A). After UVB application Bcl-2 levels decrease significantly (p<0.05, indicated by an asterisk) in NRP1-deficient epidermis and cells, whereas control tissue and cell extracts show no significant changes in Bcl-2 amounts. …”

The result of applying the OKO method on eciML1515 model for overproducing 41 native metabolites of <i>E</i>. <i>coli</i>. by Zahra Razaghi-Moghadam (1426774)

“…The numbers of Kcat that are required to increase and decrease are respectively given in columns H and I, and the sum of fold-changes for Kcats is given in column M. …”

Pretreatment with 6-paradol reduces NO production, cytotoxicity, and iNOS upregulation in LPS-stimulated BV2 microglia. by Bhakta Prasad Gaire (706189)

“…Values presented per each band indicate fold decrease compared with LPS alone. n = 3 per group. …”