Ethanol and Reactive Species Increase Basal Sequence Heterogeneity of Hepatitis C Virus and Produce Variants with Reduced Susceptibility to Antivirals by Scott Seronello (197476)

“…Human hepatoma cells supporting a continuous replication of genotype 1b HCV RNA (Con1, AJ242652) were exposed to ethanol, acetaldehyde, hydrogen peroxide, or <em>L-</em>buthionine-<em>S,R</em>-sulfoximine (BSO) that decreases intracellular glutathione as seen in patients. …”

Deciphering the molecular players that govern the SIN1-mTORC1 biphasic dependency. by Milad Ghomlaghi (11442533)

“…To generate the SIN1-pS6K1response curve for a specified parameter set, we gradually increase SIN1 expression within the range = [0.01, 1000] folds of the nominal value and we simulated the corresponding pS6K1 level and obtained its steady state value. …”

Representative examples from the Mg titration of individual molecules by Andrei Yu. Kobitski (29840)

“…<p><b>Copyright information:</b></p><p>Taken from "Mg-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis"</p><p></p><p>Nucleic Acids Research 2007;35(6):2047-2059.…”

Secondary structures of α-synuclein retained after temperature pretreatments and were fully reversible upon temperature denaturation. by Winny Ariesandi (275766)

“…The CD signals at 222 nm were monitored and the molar ellipticity is plotted. The data showed a completely reversible folding of α-synuclein in response to temperature. …”

C8–C10 MCFAs bind and Stabilize PPARγ LBD <i>in vitro</i>. by Marcelo Vizoná Liberato (162662)

“…TZDs (rosiglitazone, rosi, pioglitazone, pio, 0.1 mM) reduce fluorescence index, indicative of ligand-induced folding. In parallel, decreases in fluorescence index were obtained with OA (C8), NA (C9), DA (C10) and LA (C12) but not HA (C6) (all at 1 mM final concentration). …”

Table_5_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Table_2_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Data_Sheet_1_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Table_4_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Presentation_1_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.PDF by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Table_1_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.DOCX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

Table_3_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

“…<p>The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. …”

The Finding of Nondissolving Lysozyme Crystals and Its Significance for the Study of Hard-to-Crystallize Biological Macromolecules by Cecília Ferreira (2131300)

“…The disturbances in the phase transition processes are explained as the result of the changed chemical potential due to different folding states. In a time when the high-hanging fruits in structural biology have to be picked, the present findings call attention to interfacial phenomena as an important, though often imperceptible, aspect that affects protein stability and justifies further optimization of current crystallization methods.…”

Inactivation of VCP/ter94 Suppresses Retinal Pathology Caused by Misfolded Rhodopsin in <em>Drosophila</em> by Ana Griciuc (243073)

“…The mechanisms responsible for the recognition and clearance of misfolded Rh^P23H and their relevance to photoreceptor neuron (PN) degeneration are poorly understood. Folding-deficient membrane proteins are subjected to Endoplasmic Reticulum (ER) quality control, and we have recently shown that Rh^P23H is a substrate of the ER–associated degradation (ERAD) effector VCP/ter94, a chaperone that extracts misfolded proteins from the ER (a process called retrotranslocation) and facilitates their proteasomal degradation. …”

ePoster Vascular Discovery 2020 MDG.pdf by Marco De Giorgi (14580523)

“…Given the important role for N-linked glycosylation in protein folding in the ER, we hypothesized that depletion of dolichol, a scaffold for synthesis of N-linked glycans, could be responsible for the hepatocyte ER stress. …”

ATVB presentation 5-10-2019.pptx by Marco De Giorgi (14580523)

“…Given the important role for N-linked glycosylation in protein folding in the ER, we hypothesized that depletion of dolichol, a scaffold for synthesis of N-linked glycans, could be responsible for the hepatocyte ER stress. …”

Genome-Wide Analysis of Selective Constraints on High Stability Regions of mRNA Reveals Multiple Compensatory Mutations in <i>Escherichia coli</i> by Yuanhui Mao (138418)

“…We found that HSR tends to adjust the folded conformation to reduce the harm of mutations, showing a high level of mutational robustness. …”

Characteristics of thermal paper handling by study participants. by Meghan R. Bernier (4060141)

“…<p>A) In most of the dining stations, individuals handled thermal paper for 10–12 minutes. …”

Regular spiking neuron (sustained chopper) that exhibits accurate identification of envelope frequency from its spike trains. by Chris Scholes (3309477)

“…<p><b>a.</b> PSTH of the response to a pure tone at the characteristic frequency of the neuron. …”

Ultrasonic-assisted synthesis of wood-aluminium-based sorbents: Comparison with conventional preparation and evaluation of chromium removal by Nena Velinov (13216155)

“…The synthesis reaction time decreases about 5 folds using ultrasonic energy compared to the conventional method without sonication. …”