Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

“…Formation of the eye is a multi-step, dynamic process; it involves evagination of the optic vesicle, followed by distal and ventral invagination, leading to the formation of a two-layered optic cup with a transient optic fissure. …”

DataSheet1_Efficient Unnatural Protein Production by Pyrrolysyl-tRNA Synthetase With Genetically Fused Solubility Tags.pdf by Nikolaj G. Koch (12101261)

“…We show that the solubility and folding of these engineered enzymes can become a bottleneck for the production of ncAA-containing proteins in vivo. …”

Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

“…Formation of the eye is a multi-step, dynamic process; it involves evagination of the optic vesicle, followed by distal and ventral invagination, leading to the formation of a two-layered optic cup with a transient optic fissure. …”

Changes in the Proteome of Langat-Infected <i>Ixodes scapularis</i> ISE6 Cells: Metabolic Pathways Associated with Flavivirus Infection by Jeffrey M. Grabowski (740800)

“…Finally, Trichostatin A and Oligomycin A increased and decreased LGTV replication <i>in vitro</i> in ISE6 cells, respectively.…”

Discovery and characterization of disulfide–rich Tv1 teretoxin. by Prachi Anand (548595)

“…<p>An integrated approach for characterizing sample limited disulfide peptidic natural products was applied: a) RP-HPLC on-line separation of <i>Terebra variegata</i> venom (highlighted is the region where the sequenced peptide eluted). b) ETD and CAD MS/MS analysis recorded on the native peptide to determine the sequence of Tv1 peptide. c) RP-HPLC of linear and folded versions of chemically synthesized Tv1 peptide. d) MS/MS spectrum of partially reduced and alkylated Tv1 used to determine the disulfide connectivity. e) NMR solution structure of folded Tv1 peptide. f) Bioactivity of 20 μM of Tv1 (−) versus normal saline (NS) (−) solution injected into polychaete worms. …”

Bode plot of autoregulations. by Yong-Jun Shin (184085)

“…The magnitude is shown in both folds (<i>M</i>) and dB (20log₁₀<i>M</i>). …”

Acoustic parameters of voices of women in post-menopause by Renata D'Arc Scarpel (12818055)

“…These acoustic parameters are related to changes in the vibratory pattern of the vocal folds (vibration cycle). A harmonic noise ratio was above 15.000 in all women, but also had lower values with increasing age, with no statistical significance. …”

Analysis of the Yeast Peptidome and Comparison with the Human Peptidome by Sayani Dasgupta (104387)

“…Most yeast and humans peptides are derived from a subset of abundant proteins, many with functions involving cellular metabolism or protein synthesis and folding. …”

Langmuir−Blodgett Films of Amphiphilic Bis(tetrathiafulvalene) Macrocycles with Four Alkyl Chains by Tomoyuki Akutagawa (1358634)

“…The CT salt of the amphiphilic bis(TTF)-macrocycle having a [24]crown-8 ring system formed a uniform surface morphology on mica. …”

Intersubunit Ionic Interactions Stabilize the Nucleoside Diphosphate Kinase of <em>Mycobacterium tuberculosis</em> by Florian Georgescauld (385363)

“…The mutation also decreased stability to denaturation by urea and guanidinium. …”

Non-alcoholic fatty liver disease in mice with heterozygous mutation in TMED2 by Wenyang Hou (4348459)

“…Histological and molecular analysis of livers from heterozygous mice carrying the 99J mutation, <i>Tmed2</i>^<i>99J/+</i>, revealed a requirement for TMED2 in liver health. We show that <i>Tmed2</i>^<i>99J/+</i> mice had decreased levels of TMED2 and TMED10, dilated endoplasmic reticulum membrane, and increased phosphorylation of eIF2α, indicating ER-stress and activation of the UPR. …”

DataSheet1_Case report: further delineation of AEBP1-related Ehlers–Danlos Syndrome (classical-like EDS type 2) in an additional patient and comprehensive clinical and molecular re... by Tomomi Yamaguchi (6843290)

“…Light microscopic analyses showed increased interfibrillar spaces in the reticular dermis, a disorganized arrangement of collagen fibers, and decreased collagen content. …”

Role of CN in the early phases of ER stress. by Mariana Bollo (244365)

“…CLNX is also interacting with the ribosome, increasing the capacity of protein folding. PERK is associated with BiP, which prevents its autophosphorylation. …”

Polar or Apolar—The Role of Polarity for Urea-Induced Protein Denaturation by Martin C. Stumpe (269995)

“…<div><p>Urea-induced protein denaturation is widely used to study protein folding and stability; however, the molecular mechanism and driving forces of this process are not yet fully understood. …”

Table 1_Pan-cancer multi-omics analysis of CCT4 in tumor progression and cancer immunity, with focus on lung adenocarcinoma.docx by Yonghui Wu (171826)

“…The chaperonin TRiC/CCT complex, which mediates the folding of cytoskeletal and signaling proteins, has been associated with oncogenesis; however, the specific role of its subunit CCT4 in tumor–immune interactions remain unclear.…”

PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes by Aidan I. Brown (509994)

“…<div><p>Peroxisomes are membrane-bound organelles within eukaryotic cells that post-translationally import folded proteins into their matrix. Matrix protein import requires a shuttle receptor protein, usually PEX5, that cycles through docking with the peroxisomal membrane, ubiquitination, and export back into the cytosol followed by deubiquitination. …”

Data Sheet 1_Pan-cancer multi-omics analysis of CCT4 in tumor progression and cancer immunity, with focus on lung adenocarcinoma.docx by Yonghui Wu (171826)

“…The chaperonin TRiC/CCT complex, which mediates the folding of cytoskeletal and signaling proteins, has been associated with oncogenesis; however, the specific role of its subunit CCT4 in tumor–immune interactions remain unclear.…”

The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of <em>HAC1</em> RNA by Nikoleta G. Tsvetanova (149142)

“…Decreasing expression of the Ypt1 protein resulted in a reduced rate of <em>HAC1</em> RNA decay, leading to significantly increased levels of both unspliced and spliced <em>HAC1</em> RNA, and delayed attenuation of the UPR, when ER stress was relieved. …”

Histopathological scores and histopathologies of EAU mice. by Kayo Suzuki (166737)

“…<p>(A) The score of those treated with anti-Ang2 antibody was lower than that of those treated with control IgG antibody (n = 18–20 eye per group, P<0.05). …”

Experiment 2. by Lalit Pandey (13195488)

“…Once the models were trained, performance decreased as a function of architecture size. Learning allowed smaller CNNs to achieve similar (or better) fits to the environment than larger CNNs, despite the smaller CNNs starting with weaker hardcoded spatial knowledge. …”