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27981
Enzymatic activity comparison.
Published 2016“…Relative to Krystexxa<sup>®</sup>, <i>Arthrobacter globiformis</i> uricase had a 2 fold better kcat and <i>Deinococcus geothermalis</i> uricase had a 2 fold better K<sub>M</sub> (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167935#pone.0167935.t004" target="_blank">Table 4</a>).…”
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27982
Effect of <i>CYP6d5</i> knockdown in Drosophila caffeine metabolism.
Published 2015“…<p>A- The comparison of the normalized quantities of caffeine metabolites reveals a dramatic decrease of theobromine combined with a substantial increase of M2 in <i>CYP6d5</i> silenced flies (ds<i>CYP6d5</i>/<i>Actin</i>-GAL4) compared to the two transgenic parental controls (<i>Actin</i>-GAL4/+, ds<i>CYP6d5</i>/+). …”
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27983
sAPPα, sAPPβ and sAPP-Fc induce Egr1 expression.
Published 2011“…<p>(<b>A</b>) Real time PCR for each recombinant protein added to 1DIV neurons for 50 minutes shows a 2-fold increased expression of Egr1 compared to controls (Ctrl). …”
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27984
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27985
Hematopoietic bone marrow (BM) colony-forming units from exposed and shielded humerus.
Published 2015“…The exposed areas showed a dose-dependent decrease 1d after exposure and there’s a start of recovery at 42d. …”
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27986
Cell death is triggered at nighttime as part of the diurnal synchronized program of <i>D.salina</i>.
Published 2013“…Live cell concentration measured using flow cytometry are indicated with blue (pure culture) and red (co-culture) points while lines are fitted model simulations. Green boxed region indicates time frame reported in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062595#pone-0062595-g003" target="_blank"><b>Fig. 3D</b></a> over which caspase-3 activity was assayed. …”
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27987
Imbalanced SCP dynamics disturb neurite outgrowth.
Published 2019“…Numerical simulations propose that decreasing stabilization leads to a significant decrease in NOG outgrowth over the investigated time. …”
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27988
MCF7-luc-GFP-mCherry breast tumor response to administration of BPR0L075 observed by bioluminescence.
Published 2012“…<p>(A, B) BLI of the same mouse as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043314#pone-0043314-g001" target="_blank">Figure 1</a> with images obtained within 15 mins after administration of luciferin s.c. immediately after the FLI; (C) Dynamic BLI showing evolution of signal intensity for the MCF7-luc-GFP-mCherry tumor shown in “A” over 40 minutes; respective curves show baseline (blue diamonds), together with 2 (red squares), 4 (green triangles), 6 (open circles) and 24 (yellow circles) hours after administration of drug carrier vehicle; (D) Dynamic BLI with respect to treatment with BPR0L075 (50 mg/kg i.p.): baseline (same as 24 hour time point in “A”, yellow circles); 2 hours after drug (red squares), 6 hours after drug (open circles) and 24 hours after drug (green triangles); (E) Normalized maximum bioluminescent signal observed in the first 15 mins post luciferin injection at each time point sequentially for individual mice over 24 hours with respect to carrier vehicle (n = 3, dashed lines) or drug (n = 3; solid lines). …”
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27989
Effects of <i>S. flexneri</i> upon morphology of submucosal neurons.
Published 2013“…(C) In addition, quantitative analysis revealed that M90T induced a decrease in intensity of NSE labelling as compared to BS176 (n = 8, p<0.001). …”
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27990
Schwann cell IR and remyelination in the injured sciatic nerve.
Published 2013“…We observed a decrease in MBP IR ratio both for WT and <i>GFAP<sup>–/–</sup>Vim<sup>–/–</sup></i> mice but did not detect any difference between the two groups of mice (D). …”
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27991
Abnormal spermatogenesis in NOTCH1 gain-of-function mice.
Published 2013“…<p>A. Decrease in the testes weight in 50-, 140-, and 400-day-old mutant vs littermate control males. n≥3 in each group. …”
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27992
Supplementary Material for: Comparison of urinary protein/creatinine ratio as an alternative to 24-hour proteinuria in Lupus Nephritis: TUNARI study
Published 2023“…Results: We compared 112 samples of 75 patients with LN, with a mean age of 34.5 ± 11.8 years. Of these patients, 85% were women, 87.9% were non-white. …”
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27993
Regulation of spine neck resistance does not generate robust changes in synaptic efficacy.
Published 2013“…Following a 20-fold decrease in spine neck resistance, the same synaptic conductance generates a 1.14 mV EPSP at the spine head, and a 0.77 mV EPSP in the dendritic shaft: a boost of synaptic efficacy (“LTP") of 7.1%. …”
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27994
Protection afforded by immunization with <i>C. gattii</i> cell wall and cytoplasmic protein preparations.
Published 2014“…<p>BALB/c mice were mock-immunized with endotoxin free PBS or immunized with total cell wall proteins (CW), cytoplasmic proteins (CP), or a combined CW and CP protein preparation (CW/CP) in 50 µl of sterile PBS by nasal inhalation. …”
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27995
Table_1_Fungicide sensitivity levels in the Lithuanian Zymoseptoria tritici population in 2021.docx
Published 2023“…<p>Zymoseptoria tritici causes the disease known as septoria leaf blotch in winter wheat and is a major factor in yield loss worldwide. Farmers are inclined to use fungicides to protect their crops; however, the efficacy of these measures is rapidly decreasing due to the natural mechanisms of mutation emergence in pathogen populations. …”
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27996
MEKi inhibits growth and ablates MAPK regardless of <i>PIK3CA</i><sup><i>mut</i></sup> status.
Published 2018“…<p>Selumetinib IC<sub>50</sub> were similar regardless of <i>PIK3CA</i><sup><i>mut</i></sup> status in NHA (<b>A</b>), but slightly higher in most <i>PIK3CA</i><sup><i>mut</i></sup> NHA<sup>RAS</sup> compared to parental cells (*, P≤0.03) (<b>B</b>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200014#pone.0200014.s011" target="_blank">S11 Fig</a></b>). …”
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27997
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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27998
The role of exosomal hsa-miR-125b-5p and hsa-miR-320c as non-invasive biomarkers in high-radon areas of Kazakhstan
Published 2025“…</p> <p>Results revealed a 25.4-fold increase in hsa-miR-125b-5p and a 12.5-fold decrease in hsa-miR-320c in participants exposed to high-radon levels compared to controls. …”
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27999
R117H-7T and R117H-5T function (+/-) ivacaftor: estimates from <i>in vitro</i> measurements of channel function and transcript analysis.
Published 2017“…The 5T mutation causes a large decrease in full-length transcripts and when combined with R117H reduces function to ~1.5% (column 3) and to 0.75% when the other allele is non-functional (column 4). …”
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28000
The relative contribution of TAK1 and MAPK pathways in fibronectin DAMP induced expression of pro-inflammatory genes.
Published 2023“…Fold regulation of gene expression for each cell line was determined using RT-PCR and a list of genes with ≥5-fold decrease in expression compared to control treated cells were generated. …”