Identification of epitope of the G8 mAb. by Jacquelyn Gerhart (552473)

“…For each mutant clone, the mean binding value was plotted as a function of expression represented by control antibody reactivity. …”

Low fertility and postponement of first birth in Brazil by Adriana Miranda-Ribeiro (7453322)

“…Results show the persistence of regional differentials and point to (i) a scenario of postponement of first child in Brazil; and (ii) an increase in the proportion of childless women. …”

Sensitivity analysis results for single-macrophage initial conditions (ODE and ABM). by Sarah B. Minucci (17847238)

“…Variables with a nonzero change for at least one variable and time point are shown. …”

Q index and reachability across thresholds. by Kathleen M. Gates (539016)

“…., reachability) and visual depiction (grey, dotted lines) of approach for defining the point at which reachability begins to decrease (middle panel); Q values (bottom panel) up until drop in reachability (denoted with a red circle in the middle panel). …”

Controlling the G-protein signaling of Rs1 by Wei Chun Chang (43479)

“…<p>Constitutive signaling and ligand-induced signaling of Rs1 were successfully controlled by point mutations, drug choice, and domain swapping. …”

Dopaminergic cell survival in Substantia Nigra. by Vanesa Sanchez-Guajardo (254455)

“…<p>Graph illustrates the estimation of total dopaminergic neurons in SN (expressed as % of control, contralateral side values) using stereological tools in all groups and time points. A significant decrease of the number of TH+ cells was observed in the α-syn-cell death group at all time points. …”

Effect of BAPTA-AM and ABT-737 on ionomycin-induced Δψ_m. by Daniel Tornero (218854)

“…Afterwards, cells were washed in Krebs solution and Ionomycin (2 µM; Iono) was added and Δψ_m was measured on-line as a decrease in TMRM fluorescence. Each data point represents mean ± S.E.M. of 15 individual cells from 3 different experiments.…”

MIF secretion is induced by IR. by Yashi Gupta (844021)

“…<p>A) Western blot of RCC4 cells treated with 4 Gy IR and lysed at various time points after exposure stained with phosphoserine 15 p53, MIF, and β-actin antibodies. …”

Isolated hypothalamic neurons from E19 embryos. by Kinning Poon (469702)

“…In the HFD compared to chow embryos, there was a statistically significant decrease in the number of YAP-labeled neurons and an increase in the number of TEF- and ENK-labeled neurons. …”

Kinetics of DNA repair in polymerase epsilon target in adults following 400 J/mUVC by Joel N Meyer (32917)

Hs-TnT values variation (delta) from baseline to 1-year follow-up. by Isabelle Ethier (539502)

“…Every point on the graph represents a patient.</p>…”

Theoretical analysis of electrode size. by Sadullah Canakci (4439137)

“…<b>(b)</b> Amplitude of sharp waves is plotted as a function of electrode area. <b>(c)</b> Amplitude of ripples is plotted as a function of electrode area.…”

Fas2 interacting partner IgCAMs Fipi and Elff are required for imaginal disc development. by Luis Garcia-Alonso (152388)

“…While the fas2 RNAi produces a strong decrease in MAPK activation with respect to the control siblings (see also [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0309891#pone.0309891.ref008" target="_blank">8</a>]), the combined expression of fipi and elff RNAis produces a significant increase.…”

Categorizing referred SSc patients with normal and reduced exercise capacity, using cardiopulmonary exercise testing. by Daniel Dumitrescu (329168)

“…Nine of the 11 patients classified as pulmonary vasculopathy had a decreasing P_ETCO₂. Two had either no change or increasing P_ETCO₂ from the start of exercise to the <i>AT</i>, possibly due to lung restriction. …”

Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Antiprotease activity of HE-4 at different concentration and at different condition against various serine, cystine and aspartic proteases. by Nirmal Chhikara (124762)

“…EDTA was added to ZnCl₂ pre-treated HE-4 to check whether it can rescue the decrease in activity induced by ZnCl_2. SDS control is the % inhibition of trypsin by 5% SDS and 5% SDS point is the activity of SDS-pretreated HE-4 against trypsin. …”