The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling by Kine Andenæs (5566217)

“…Fibromodulin was 3-10-fold upregulated in hearts of heart failure patients and mice. …”

Activation of the Canonical Wnt/β-Catenin Pathway in ATF3-Induced Mammary Tumors by Leqin Yan (231387)

“…Several positive-acting ligands for this pathway, including <em>Wnt3</em>, <em>Wnt3a</em>, <em>Wnt7b</em>, and <em>Wnt5a</em>, are significantly overexpressed in tumor tissue, and mRNA for <em>Wnt3</em> is about 5-fold more abundant in transgenic mammary tissue than in non-transgenic mammary tissue. …”

Image_1_Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice.PDF by Ana C. Marques (149564)

“…We observed that pravastatin induced higher H₂O₂ production rate (40%), decreased activity of aconitase (28%), a superoxide-sensitive Krebs cycle enzyme, and increased susceptibility to Ca²⁺-induced MPT (32%) in liver mitochondria. …”

Image_1_Transgenic tobacco plant overexpressing ginkgo dihydroflavonol 4-reductase gene GbDFR6 exhibits multiple developmental defects.tif by Jun Ni (68173)

“…<p>Dihydroflavonol Q 4-reductase (DFR), a key enzyme in the flavonoid biosynthetic pathway in plants, significantly influences plant survival. …”

Bioactive constituents of <i>Salvia przewalskii</i> and the molecular mechanism of its antihypoxia effects determined using quantitative proteomics by Yafeng Wang (330852)

“…In addition, a total of 28 proteins were differentially expressed in lung of hypoxia + SPM group (fold change > ± 1.2 and <i>p</i> < 0.05). …”

Climbing ability of teneral and sclerotized adult bed bugs and assessment of adhesive properties of the exoskeletal fluid using atomic force microscopy by Kevin R. Hinson (4688446)

“…Using atomic force microscopy (AFM), we found that adhesion force of an exoskeletal (presumably molting) fluid decreased almost five-fold from 88 to 17 nN within an hour of molting. …”

Data_Sheet_1_Dynamism of Metabolic Carbon Flow of Starch and Lipids in Chlamydomonas debaryana.pdf by Naoki Sato (78889)

“…Most fatty acids showed rapid and slow components of metabolism, whereas oleic acid decayed according to a single exponential curve. Highly labeled population of fatty acids that accumulated during the initial labeling decreased rapidly, and replaced by low abundance population during the chase time, indicating that highly labeled fatty acids were degraded and the resulting carbons were re-used in the re-synthesis with about 9-fold unlabeled, newly fixed carbons. …”

Table_1_Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women.PDF by Karol Gliniewicz (3538301)

“…The vaginal communities of most postmenopausal women receiving HT (10/15) were dominated by species of lactobacilli and belonged to clusters A, C, and F (P < 0.001). This sharply contrasts with vaginal communities of postmenopausal women without HT, most of which (10/15) were in cluster D, depleted of lactobacilli, and had about 10-fold fewer total bacteria (P < 0.05). …”

Enhancement of Anti-Inflammatory Activity of <i>Aloe vera</i> Adventitious Root Extracts through the Alteration of Primary and Secondary Metabolites via Salicylic Acid Elicitation by Yun Sun Lee (498030)

“…Transcript accumulation analysis of polyketide synthase genes and gas chromatography mass spectrometry showed that these secondary metabolic changes resulted from increased expression of octaketide synthase genes and decreases in malonyl-CoA, which is the precursor for the tricyclic aromatic quinone biosynthesis pathway. …”

Additional file 3 of MALAT1 knockdown alleviates the pyroptosis of microglias in diabetic cerebral ischemia via regulating STAT1 mediated NLRP3 transcription by Nan Zhao (351674)

Structural and Electronic Noninnocence of α‑Diimine Ligands on Niobium for Reductive C–Cl Bond Activation and Catalytic Radical Addition Reactions by Haruka Nishiyama (1584853)

“…During the catalytic reaction, the α-diimine ligand smoothly released and stored an electron to control the oxidation state of the niobium center by changing between an η⁴-(σ²,π) coordination mode with a folded MN₂C₂ metallacycle and a κ²-(<i>N</i>,<i>N</i>′) coordination mode with a planar MN₂C₂ metallacycle. …”

General methodology of integrative, cell based transport modeling. by Jing-yu Yu (181194)

“…<b>D</b>) Experimental design of insert system with patterned pore arrays on membrane support for viewing lateral transport of fluorescent molecules along the plane of a cell monolayer, away from a point source. <b>E</b>) Transmitted light image of a 5×5, 3 µm diameter pore array (20 µm spacing) on a polyester membrane. …”

Enhancement the Fatigue Life of Floating Breakwater Mooring System Using Tuned Liquid Column Damper by Mostafa Shahrabi (7316696)

“…This paper presents a further parametric study focused on the effect of TLCD on fairlead point displacement, mobilized tension, damage rate, and fatigue life of mooring lines. …”

Discrete and smoothed pairwise invasibility plots at five planting densities for the Weak and Strong lamina response scenarios. by Franca J. Bongers (7296353)

“…See the main text for detailed explanation of how to read pairwise invasibility plots. In short, the point where the identity line and a second isoclines (if present) intersect corresponds to a singular strategy that could represent a cESS.…”

DataSheet_1_Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.docx by Fuliang Zong (13827097)

“…To test this, colony stimulating factor 2 receptor alpha (Csf2ra) knockout (KO) mice that lack GM-CSF signaling and wild-type (WT) mice models of intratracheal exposure to a lethal dose (2× LD₅₀) of RT were established. …”

Effects of three sesquiterpene compounds from volatile oil of <i>Dalbergia odorifera</i> T. Chen on pERK1/2, ERK1/2, PPARγ and HO-1 expression in LPS-stimulated RAW264.7 macrophage... by Xiang Li (114679)

“…<p>(A). LPS co-incubation induced significant increase of pERK1/2 expression, the ratio of pERK1/2 to ERK1/2 was higher than that in the control group (*<i>p</i><0.05). 50 µM ENL attenuated the increased ratio of pERK1/2 to ERK1/2, while 50 µM SDL suppressed this ratio compared to LPS treated alone (#<i>p</i><0.05), and RDL had no effect on the increased ratio. …”

Trajectory of disability and quality-of-life in non-geriatric and geriatric survivors after severe traumatic brain injury by Chiara S. Haller (3689263)

“…</p> <p><i>Methods</i>: Patients ≥ 16 years who sustained a severe TBI (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. …”

Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy by Magdalena Orczyk-Pawilowicz (2608057)

“…In the future, these results might be a useful reference point for analysis of complicated pregnancies.…”

Template-Directed Ligation of Tethered Mononucleotides by T4 DNA Ligase for Kinase Ribozyme Selection by David G. Nickens (243216)

“…Under optimized conditions, T4 DNA ligase efficiently (>90%) joined a correctly paired, or T∶G wobble-paired, substrate on the 3′ side of the ligation junction while discriminating approximately 100-fold against most mispaired substrates. …”

<strong>Bull trout streamflow and temperature linear SCR model</strong> by Patti Wohner (16398345)

“…More than 50% of spawners died and mean weekly pre-spawning apparent survival was higher in the low streamflow year (x̄ = 0.97, CI 0.93–1), compared to the higher and more variable streamflow year (x̄ = 0.91, CI 0.76–0.98). …”