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41401
ERG responses of <i>C. perspicillata</i> and <i>G. soricina</i> at mesopic conditions.
Published 2013“…With increasing background illumination, the response to a given flash intensity decreases. Squares represent the situation with no adapting light (same curve as in B). …”
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41402
Meta-analysis of 3 manipulations of the insulin/Tor signaling identifies rover-biased genes.
Published 2009“…<p>Three published studies decreased insulin/Tor effects via (A) ablation of <i>dilp3</i> expressing cells <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Buch1" target="_blank">[28]</a>, (B) overexpression of constitutively active <i>foxo </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Gershman1" target="_blank">[29]</a>, or (C) rapamycin <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Guertin1" target="_blank">[30]</a>. …”
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41403
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41404
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41405
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41406
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41407
The reinforcement of sludge-recycling enhanced flocculation by the acid activation of settled sludge
Published 2021“…In this work, the acid activation of sludge was performed using a range of pH values (1.0–6.0) and charge states, with and without long-chain bridging. …”
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41408
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41409
TMP inhibits migration in primary human trabecular meshwork cells after treatment with TGF-β1.
Published 2015“…<p>A, The number of migrative cells was determined using transwell assay. …”
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41410
Text S1 - Down-Regulating Sphingolipid Synthesis Increases Yeast Lifespan
Published 2012“…Figure S2: Myriocin treatment decreases cell size. DBY746 cells were grown with and without myriocin (Myr) as in a CLS assay using SDC medium (pH 4.5, 3X iron). …”
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41411
Human heart mtDNA topology changes in early childhood and in mitochondrial disorders involving mutations in Twinkle and PolG.
Published 2010“…<p>The basis of the assignment of the different molecular forms is presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010426#pone.0010426-Pohjoismki1" target="_blank">[5]</a>. …”
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41412
Table_2_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.docx
Published 2022“…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
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41413
Identification of Glycoprotein Markers for Pancreatic Cancer CD24<sup>+</sup>CD44<sup>+</sup> Stem-like Cells Using Nano-LC–MS/MS and Tissue Microarray
Published 2012“…Herein, the malignant phenotype of pancreatic cancer stem-like CD24<sup>+</sup>CD44<sup>+</sup> cells was isolated from a human pancreatic carcinoma cell line (PANC-1) and demonstrated 4-fold increased invasion ability compared to CD24<sup>–</sup>CD44<sup>+</sup> cells. …”
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41414
Table_1_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.xlsx
Published 2022“…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
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41415
Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
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41416
Identification of Glycoprotein Markers for Pancreatic Cancer CD24<sup>+</sup>CD44<sup>+</sup> Stem-like Cells Using Nano-LC–MS/MS and Tissue Microarray
Published 2012“…Herein, the malignant phenotype of pancreatic cancer stem-like CD24<sup>+</sup>CD44<sup>+</sup> cells was isolated from a human pancreatic carcinoma cell line (PANC-1) and demonstrated 4-fold increased invasion ability compared to CD24<sup>–</sup>CD44<sup>+</sup> cells. …”
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41417
Presentation_2_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx
Published 2022“…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
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41418
GD3 Synthase Overexpression Sensitizes Hepatocarcinoma Cells to Hypoxia and Reduces Tumor Growth by Suppressing the cSrc/NF-κB Survival Pathway
Published 2009“…<div><h3>Background</h3><p>Hypoxia-mediated HIF-1α stabilization and NF-κB activation play a key role in carcinogenesis by fostering cancer cell survival, angiogenesis and tumor invasion. …”
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41419
Presentation_3_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx
Published 2022“…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
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41420
Presentation_1_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx
Published 2022“…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”