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41741
Partial Agonist, Telmisartan, Maintains PPARγ Serine 112 Phosphorylation, and Does Not Affect Osteoblast Differentiation and Bone Mass
Published 2014“…TEL decreased <sup>S273</sup>pPPARγ and did not affect <sup>S112</sup>pPPARγ levels in a model of marrow MSC differentiation, U-33/γ2 cells. …”
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41742
Effects of the D1-like receptor antagonist SCH-23390 (20 μM) on the excitability of RA PNs.
Published 2013“…<p>A. In the presence of DA (50 μM), SCH-23390 (20 μM) inhibits the increase in evoked firing. …”
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41743
The number of sampling cercariae and snails affected the coverage of alleles.
Published 2025“…The red dotted line shows 85% of the total <i>Na</i> for 23 loci (except p6), which reached the plateau; the black dotted line shows 50% of the total <i>Na</i>. The standard deviation of <i>Na</i> among replicates for each locus progressively decreased with the increased number of snails.…”
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41744
Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications
Published 2017“…Below the <i>T</i><sub>g</sub> zone, the elastic modulus of all formulations decreased by about 1000 fold. That property gave rise to a robust shape memory effect (SME), the quality of which was evaluated via several figures of merit that were calculated from tensile stretching data over five temperature cycles between <i>T</i><sub>g</sub> + 10 °C and <i>T</i><sub>g</sub> – 40 °C. …”
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41745
Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications
Published 2017“…Below the <i>T</i><sub>g</sub> zone, the elastic modulus of all formulations decreased by about 1000 fold. That property gave rise to a robust shape memory effect (SME), the quality of which was evaluated via several figures of merit that were calculated from tensile stretching data over five temperature cycles between <i>T</i><sub>g</sub> + 10 °C and <i>T</i><sub>g</sub> – 40 °C. …”
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41746
Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications
Published 2017“…Below the <i>T</i><sub>g</sub> zone, the elastic modulus of all formulations decreased by about 1000 fold. That property gave rise to a robust shape memory effect (SME), the quality of which was evaluated via several figures of merit that were calculated from tensile stretching data over five temperature cycles between <i>T</i><sub>g</sub> + 10 °C and <i>T</i><sub>g</sub> – 40 °C. …”
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41747
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41748
Discovery of thiazolidinedione-based pancreatic lipase inhibitors as anti-obesity agents: synthesis, <i>in silico</i> studies and pharmacological investigations
Published 2024“…Compound <b>18a</b> presented the most potent PL inhibitory activity with IC<sub>50</sub> = 2.71 ± 0.31 µM, as compared to the standard drug, Orlistat (IC<sub>50</sub> = 0.99 µM). …”
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41749
Temporal Gene Expression Profiling during Rat Femoral Marrow Ablation-Induced Intramembranous Bone Regeneration
Published 2010“…Adipogenic marker genes were found within variable/decreased expression groups, emphasizing that adipogenesis was inhibited during osteogenesis. …”
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41750
Overexpression of POLDIP3 inhibits PDCoV replication in IPEC-J2 cells.
Published 2023“…(F) POLDIP3 overexpression decreased PDCoV infection by TCID<sub>50</sub> assay. …”
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41751
Correlation of Clinical Trachoma and Infection in Aboriginal Communities
Published 2015“…</p> <h3>Methods</h3><p>A consensus fine grading of trachoma, based on clinical assessment and photograding, was compared to PCR, a lipopolysacharide (LPS)-based point-of-care (POC) and a 16S RNA-based nucleic acid amplification test (NAAT). …”
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41752
Plasma proteins associated with whole brain volume in Alzheimer's disease.
Published 2011“…<b>B</b>. The result of a seven-round cross validation exercise in which every point represents test data not used in the model-building. …”
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41753
Rapid and long-lasting antidepressant-like effects of ketamine and their relationship with the expression of brain enzymes, BDNF, and astrocytes
Published 2021“…Imipramine (IMI, 30 mg/kg, ip), a tricyclic antidepressant drug, was used as reference. …”
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41754
DataSheet_1_Climate drivers of Southern Ocean phytoplankton community composition and potential impacts on higher trophic levels.pdf
Published 2022“…In contrast, simulated reductions in ice cover yield greater light penetration in the SIZ, generating a phenological advance in the bloom accompanied by a shift to more small phytoplankton that effectively consume available iron; the result is an overall increase in net primary production, but a decreasing proportion of diatoms. …”
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41755
The evolutionary dynamics of molecular number of NSR in the modeling.
Published 2021“…(<b>b</b>) A case we assumed as the starting point for the machine-learning. …”
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41756
High-Throughput Molecular Dynamics Simulations and Validation of Thermophysical Properties of Polymers for Various Applications
Published 2020“…Such polymers have a point of discontinuity on the specific volume vs temperature plot, which we associate with the melting temperature (<i>T</i><sub>m</sub>). …”
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41757
Changing the concentration of the inducer.
Published 2024“…<p>(A) Average mutual information at the repressor binding site decreases as the inducer concentration increases. …”
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41758
Longitudinal study of body mass index, dyslipidemia, hyperglycemia, and hypertension in 60,000 men and women in Sweden and Austria
Published 2018“…We included paired examinations performed 10±2 years apart and used them for longitudinal analysis with linear regression of changes between the ages 30 and 40, 40 and 50, or 50 and 60 years.</p><p>Results</p><p>Higher levels of BMI were associated with increases in glucose and mid-blood pressure as well as triglycerides levels, and, to a lesser extent, decreases in cholesterol levels. …”
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41759
qRT-PCR analysis of RPE and retinal- specific genes in homozygous <i>Mfrp<sup>rd6</sup></i>, <i>Tulp1<sup>tvrm124</sup> and Rpe65<sup>tvrm148</sup></i> mutants.
Published 2014“…<p>(A) In homozygous <i>Mfrp<sup>rd6</sup></i> mutant mice, the transcripts in the visual cycle (<i>Rpe65, Lrat</i> and <i>Rgr</i>), phototransduction pathway (<i>Rgs9</i>, <i>GuCa1b</i>, <i>Pde6a</i>) and structural components of rods and cones (<i>Fscn2</i> and <i>RpGrip1</i>) were significantly decreased relative to the wild-type control (B6/J), validating the microarray results. …”
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41760
Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B.
Published 2025“…Representative western blots were cropped from respective western blot images for the protein of interest and grouped together. GAPDH was used as a reference protein. <b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. …”