TRPP2 and TRPV4 Form an EGF-Activated Calcium Permeable Channel at the Apical Membrane of Renal Collecting Duct Cells by Zhi-Ren Zhang (446816)

“…With loss of cilia, apical EGF treatment resulted in 64-fold increase in channel activity in cilia (-) but not cilia (+) cells. …”

Development of HK2 spheroid <i>in vitro</i> culture model and evaluation of kidney injury biomarkers. by Acharya Balkrishna (5640038)

“…<b>(C)</b> P-gp function analysis by Calcein-AM (0.5 μM) reagent on Vancomycin (2 mM) and Renogrit (10, 30, and 100 μg/mL) or NAC (4 mM) co-treated HK2 spheroids by evaluation of difference in fold of fluorescence intensity. Renogrit treatment decreased the Vancomycin (2 mM) stimulated release of nephrotoxicity biomarkers, <b>(D)</b> NAG (U/L) and <b>(E)</b> KIM-1 (pg/mL). …”

Pharmacokinetics and pharmacodynamics after treatment of DIO-mice with HI, X10 and IGF-1 by sc injection. by Henning Hvid (486358)

“…<p>A: Plasma concentrations measured in mice treated with HI, X10 or IGF-1. …”

DataSheet_1_Humoral, Cellular and Cytokine Immune Responses Against SARS-CoV-2 Variants in COVID-19 Convalescent and Confirmed Patients With Different Disease Severities.docx by Chun-Hsiang Chiu (4093444)

“…Notably, the RBD-specific IgG towards the delta variant decreased by 2.5-fold compared to the alpha variant. …”

MicroRNA Stability in FFPE Tissue Samples: Dependence on GC Content by Yu Kakimoto (311787)

“…Although the read counts were increased 1.7-fold in FFPE samples, compared with those in the frozen samples, the average miRNA mapping rate decreased from 32.0% to 9.4%. …”

Effects of High-Dose Genistein on the Hypothalamic RNA Profile and Intestinal Health of Female Chicks by Zengpeng Lv (4237459)

“…Chicks exposed to high-dose genistein by intraperitoneal injection (416 ± 21, 34.5 ± 2.5) and feed supplementation (308 ± 19, 27.2 ± 2.1) both showed a reduced body weight gain and feed intake in comparison with the control group (261 ± 16, 22.7 ± 1.6, <i>P</i> < 0.01). …”

Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance by Lu-Ping Ren (183886)

“…Male C57BL/6J mice were fed either a high fructose (HFru) or high fat (HFat) diet to induce DNL or lipid oversupply in/to the liver. …”

ABL Tyrosine Kinase Inhibition Variable Effects on the Invasive Properties of Different Triple Negative Breast Cancer Cell Lines by Clément Chevalier (251823)

“…ABL inhibition by the tyrosine kinase inhibitor nilotinib is a first-line treatment for this disease. Recently, ABL has also been implicated in the transforming properties of solid tumors, including triple negative (TN) breast cancer. …”

Effects of GHS on sarcoplasmic reticulum (SR) Ca²⁺ content and phospho-phospholamban (p-PLB)/phospholamban (PLB) expression. by Yi Ma (167857)

“…<p>(A) Illustration of the SR Ca²⁺ content measurement protocol (data from cardiomyocytes exposed to ischemia/reperfusion). …”

DataSheet1_Leachability of mercury in coal fly ash from coal-fired power plants in southwest China.pdf by Yiming Huang (2195521)

“…This study demonstrated that Hg in the CFPP fly ashes was more stable under natural conditions when exposed to surface/groundwaters and had a negligible Hg leachability.</p>…”

Image_1_Knocking Down TcNTPDase-1 Gene Reduces in vitro Infectivity of Trypanosoma cruzi.TIF by Natália Lins Silva-Gomes (8594568)

“…In trypomastigote forms, the same decreasing in TcNTPDase-1 gene expression was observed to the hemi-knockout parasites. …”

Image_2_Knocking Down TcNTPDase-1 Gene Reduces in vitro Infectivity of Trypanosoma cruzi.TIF by Natália Lins Silva-Gomes (8594568)

“…In trypomastigote forms, the same decreasing in TcNTPDase-1 gene expression was observed to the hemi-knockout parasites. …”

DataSheet_1_Development of long-term primary cell culture of Macrobrachium rosenbergii: morphology, metabolic activity, and cell-cycle analysis.docx by Gurucharan Sudarshan (14348331)

“…Proliferation, based on metabolic activity, in the cultures was sustained by a significant increase in the portion of cells arrested in the S phase, from day 4 up to day 24, and then a decrease between days 45 and 90. …”

Reduction of motor proteins perturbs the bi-directional movement of TKV vesicles. by Min Jung Kang (616217)

“…<p><b>A:</b> TKV-GFP vesicles move bi-directionally in larval axons. …”

DataSheet_1_Novel Compound C150 Inhibits Pancreatic Cancer Cell Epithelial-to-Mesenchymal Transition and Tumor Growth in Mice.pdf by Tao Wang (12008)

“…C150 inhibited cell proliferation in multiple pancreatic cancer cells with IC₅₀ values of 1-2.5 μM, while in an non-cancerous pancreatic epithelial cell line hTERT-HPNE the IC₅₀ value was >12.5 μM. …”

Table_1_Cerebrospinal Fluid Osteopontin and Inflammation-Associated Cytokines in Patients With Anti-N-Methyl-D-Aspartate Receptor Encephalitis.DOCX by Shanshan Pei (680429)

Effect of fasudil on experimental autoimmune neuritis and its mechanisms of action by Yanyin Zhao (8184282)

DataSheet_5_Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model.pdf by Eun-Ah Sung (17640645)

The p38α MAPK Function in Osteoprecursors Is Required for Bone Formation and Bone Homeostasis in Adult Mice by Edgardo Rodríguez-Carballo (595134)

Data_Sheet_1_Stroke burden and attributable risk factors in China, 1990–2019.docx by Wenxin Tian (8056850)

“…</p>Results<p>From 1990 to 2019, the age-standardized incidence, mortality, and DALY rates for total stroke decreased by 9.3% (3.3, 15.5), 39.8% (28.6, 50.7), and 41.6% (30.7, 50.9) respectively. …”