Inhibiting autophagy reduces retinal degeneration caused by protein misfolding by Jingyu Yao (322837)

“…Mutations in the gene encoding RHO (rhodopsin) are a common cause of autosomal dominant retinitis pigmentosa (adRP), with the Pro23His variant of RHO resulting in a misfolded protein that activates endoplasmic reticulum stress and the unfolded protein response. …”

Combining Virtual Reality Visualization with Ensemble Molecular Dynamics to Study Complex Protein Conformational Changes by Jordi Juárez-Jiménez (1326255)

“…Detailed tests demonstrate that eMD-VR substantially decreases the computational cost of folding simulations of a WW domain, without the need to define collective variables a priori. …”

ISE6 proteins with increased expression associate with pathways for protein production, transport, assembly, and proteolysis. by Jeffrey M. Grabowski (740800)

“…“Fld, Srt, & Deg” is the folding, sorting, and degradation KEGG pathway. <b>**</b> denotes ortholog in human [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004180#pntd.0004180.ref019" target="_blank">19</a>]; + denotes human ortholog showing increased expression following HCV infection;—denotes human ortholog showing decreased expression following HCV infection. …”

Data from: Long-Distance Transportation Causes Temperature Stress in the Honey Bee, Apis mellifera (Hymenoptera: Apidae) by Dacotah Melicher (17480604)

“…Functional and enrichment analysis identified increased methylation and decreased ribosomal and protein-folding activity. Pheromone and odorant-binding transcripts were up-regulated after transportation. …”

Sensitivity of the measured scaling exponents to the threshold intensity values that select which voxels are part of the vessel lumen. by Mitchell G Newberry (789344)

“…For both of these top two panels, the number of data points decreases with threshold value as it must. …”

Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues by Erica P. Homan (249068)

“…These proteins, together with cyclophilin B (encoded by <i>PPIB</i>), form a complex that 3-hydroxylates a single proline residue on the α1(I) chain (Pro986) and has cis/trans isomerase (PPIase) activity essential for proper collagen folding. …”

Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation by Vittoria Massafra (613864)

“…Our analyses provide a resource of FGF19 target proteins in the liver. 189 proteins were upregulated (≥ 1.5 folds) and 73 proteins were downregulated (≤ -1.5 folds) by FGF19. …”

In Vivo Two-Photon Imaging of Astrocytes in GFAP-GFP Transgenic Mice - Fig 3 by Dongjun Guo (412264)

“…<p>Comparison of astrocyte number and morphological features between open-skull technique (A-D) and thinned-skull technique (E-H). (A) In the open-skull technique, the number of astrocytes decreased at 24 hr and 3 d then increased at 1wk after surgery. …”

In Vitro Transition from Bursting to Single Spiking Output Is Frequency-Dependent by Donald C Cooper (71501)

“…The arrow in (D) points to the beginning of the ADP slope in an overlay of a burst before and after a transition to a single spike at 5 Hz.…”

iModulon activities capture the effects of mutations from adaptive evolution to multiple antibiotics. by Anand V. Sastry (6619310)

“…The inversion decreases <i>lon</i> expression, resulting in longer residency times for MarA, SoxS, and RcsA.…”

Mean unfolding stability versus misfolding stability for neutrality exponent (non-neutral regime). by Raul Mendez (80807)

“…<p>The sets of points joined with solid lines correspond to constant GC usage, between (largest ) and (largest ). grows and decreases with . …”

Results of the Mann-Whitney U test and the t-test comparing boundary shift for the three forms of iterated algorithmic bias with class-dependent human action probability ratio 10:1... by Wenlong Sun (284779)

“…Random selection increases the number of points, while active learning does not have a significant effect.…”

Data_Sheet_1_Sepsis of Patients Infected by SARS-CoV-2: Real-World Experience From the International HOPE-COVID-19-Registry and Validation of HOPE Sepsis Score.docx by Mohammad Abumayyaleh (9704657)

“…A score of 1 was assigned to current smoking, tachypnoea, decreased SpO₂, decreased BP, decreased GCS, elevated PCT, TnI, and creatinine, whereas a score of 2 was assigned to hemoptysis.…”

Visualization_2.mp4 by Pedro Mece (4707142)

“…The yellow arrow points towards a capillary. When this capillary is positioned at the edge of the illumination, it is possible to visualize and track individual red blood cells. …”

Representative confocal images of connexin 26 (Cx-26) and 30 (Cx-30) labeling in the OCs. by Donald Ewert (4386493)

“…The noise exposure did not change the expression of Cx-30 in the OCs all time points after noise exposure (B2-E2). Scale bar = 20 μm in E3 for A1-E3.…”

Representative confocal images of connexin 26 (red) and 30 (green) labeling collected from the spiral ligament. by Donald Ewert (4386493)

“…Decreased connexin 26 labeling (column 1) is observed in the spiral ligament of chinchilla all time points after noise exposure (B-H) except in the treated group at 6 months after noise exposure(I). …”

Convergence properties of test cases I–III. by Keith M. Callenberg (361287)

“…Values along the x-axis are spaced using a log base 2 scale. In all graphs, the number of grid points used to achieve the grid spacing on the x-axis was 17, 33, 65, 97, 129, and 161 (). …”

Pharmaceutical films made from the waste material from the preparation of propolis extracts: development and characterization by Lucas de Alcântara Sica de Toledo (12847154)

“…Films were produced in the presence and absence of a polymeric adjuvant (gelatin or ethylcellulose) and propylene glycol by a solvent casting method. …”

Effects of Nash equilibrium speed changes with the non-sensory motor algorithm on encounters, agent numbers, and payoffs. by Hiroyuki Ichijo (13891153)

“…<b>Ha</b> indicates that <i>N</i>_<i>w</i> decreases as <i>K</i>_<i>w</i> increases (the dark brown points shift to the lower side). …”

In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol by Sampath, Chethan

“…High glucose induced toxicity decreased cell viability compared to the untreated cells and AR activity increased to 2–5 folds from 24 to 96h. …”
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