Loss of Alms1 Does Not Affect Transcriptional Changes during Ciliogenesis but Causes Impairment in Flow-Induced Mechanosensation by Guochun Li (273973)

“…</p><p>(B) Suppression of Alms1 does not affect the upregulation of <i>Bbs4</i> and <i>Ttc10</i> during ciliogenesis. N, negative siRNA; 1a, Alms1a siRNA; 1b, Alms1b siRNA.</p><p>(C<b>)</b> Heat map representation of microarray analysis of mIMCD3 during ciliogenesis. 98 genes with the most dramatic changes in expression showed approximately equivalent expression changes in the presence of a scrambled siRNA control, or in the presence of specific siRNAs that decreased <i>Alms1</i> mRNA levels and blocked cilia formation.…”

Oxidative stress in INS1E and alphaTC1 cells in monolayer culture. by Mireille M. J. P. E. Sthijns (12245491)

Variants in sensitive and secondary resistant STS cells. by Audrey Laroche (802366)

“…<p>From top to bottom rows, plots of IB111, IB115 and IB128 variants. A. AAR scatters parental (X axis) and resistant (Y axis), red points: AAR higher in resistant, blue points: AAR lower in resistant, gray points: AAR unchanged (parental variants), dotted lines: AAR difference isomers (lines of same AAR difference). …”

Table_1_Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation.docx by Kayleigh S. J. Campbell (11276013)

“…Acute SRI-related changes in fetal HRV may reflect a pharmacologic mechanism, a transient impairment in autonomic functioning, or an early adaption to altered serotonergic signaling, which may differ between males and females. …”

Structural Analysis of Alkaline β-Mannanase from Alkaliphilic <em>Bacillus</em> sp. N16-5: Implications for Adaptation to Alkaline Conditions by Yueju Zhao (231466)

“…We report the catalytic domain structure of an industrially important β-mannanase from the alkaliphilic <em>Bacillus</em> sp. N16-5 (BSP165 MAN) at a resolution of 1.6 Å. This enzyme, classified into subfamily 8 in glycosyl hydrolase family 5 (GH5), has a pH optimum of enzymatic activity at pH 9.5 and folds into a classic (β/α)₈-barrel. …”

Fluid shear stress resistance is induced by membrane damage. by J. Matthew Barnes (118311)

“…Cell debris can be seen in the “D” gate (long, narrow polygon on the left) whereas viable cells are represented by the “V” gate, which is established on forward- and side-scatter parameters that typically defines a viable cell population. For these studies, an equal number of events in the V-gate were counted at each passage, even though overall viability of the population was decreasing as documented in Fig. 1. …”

Validation of the 30 best ranked parameter combination fits using time-variant IKK2 inhibition. by Fabian Konrath (150418)

“…<p>a) A549 reporter cells were tracked and the p53 median nuclear fluorescence intensity was measured in cells treated with DMSO or IKK2i at different time points. …”

Table 6_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table 4_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Supplementary file 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.pdf by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table 3_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table 2_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table 5_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx by Ahmet Alptekin (14937405)

“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”

Table1_House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice.docx by Žana Tempels-Pavlica (18073444)

“…CARAT scores improved clinically significant by 6 points and symptomatic medication use decreased from 96.1% to 77.4%. …”

Effect of knockdown of 25-hydroxylases on 25OHD₃ generation. by Kaining Liu (294608)

“…When CYP27A1 was knocked down in hGF and hPDLC, the generation of 25OHD₃ decreased significantly compared to when CYP27A1 was not knocked down. …”

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway by Bin Wang (30851)

“…<p>Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. …”

Phenome-wide associations of clinical diagnoses with height and height genetic risk score (GRS). by Michael G. Levin (9499397)

“…<p>Phenome-wide association studies were performed in Penn Medicine Biobank participants to identify clinical phenotypes associated with increased (A) height and (B) height GRS. The horizontal red line denotes the Bonferroni-adjusted level of significance (0.05/1,816 phenotypes), the blue line denotes the nominal level of significance (0.05), and triangles denote the direction of association between increasing height and risk of the phenotype (pointing upward = increased risk; pointing downward = decreased risk).…”

Enzymatic Synthesis of Periodic DNA Nanoribbons for Intracellular pH Sensing and Gene Silencing by Gang Chen (107840)

“…Consequently, the number of folding staple strands tremendously decreases from hundreds to a few, which makes the DNR production scalable and cost-effective, thus potentially removing the barrier for practical applications of DNA nanostructures. …”

Process length and AV distribution in neurons exposed to different treatments. by Mehrdad Alirezaei (51956)

“…<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected microglia supernatant for 3 or 24 hr, however; pretreatment with rapamycin blocked this effect. *** <i>P</i><0.001, for <i>n</i> = 6 experiments. …”