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49161
Image1_Selection and Misclassification Biases in Longitudinal Studies.PDF
Published 2018“…These evaluations were either within a cross-sectional study framework, assessing biased prevalence, or for cohort study designs, evaluating biased incidence rate or risk ratio estimates based on misclassification at one of the two time-points (initial assessment or follow-up). …”
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49162
Spectroscopic and Theoretical Study of Cu<sup>I</sup> Binding to His111 in the Human Prion Protein Fragment 106–115
Published 2016“…The ability of the cellular prion protein (PrP<sup>C</sup>) to bind copper in vivo points to a physiological role for PrP<sup>C</sup> in copper transport. …”
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49163
Supplementary Material for: The evolution and visual prognosis of glial proliferation with different grades after macular hole surgery: an optical coherence tomography-based study
Published 2023“…Within 10 months, the prevalence of A-type glial proliferation significantly decreased (P<0.001), but the changes in B-type (P=0.261), C-type (P=0.151), and no glial proliferation (P=0.492) were not significant. …”
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49164
BTM analysis after infection with virulent ASFV Armenia 2008.
Published 2022“…BTM modulations were calculated as normalized enrichment scores (NES) using GSEA. Increased (red) or decreased (blue) BTMs are shown relative to each group’s respective baseline with color intensity proportional to the NES and the size of the data points proportional to the q value. …”
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49165
Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and T...
Published 2014“…There was no significant association between CYP4F2 genotypes and histological end points in either trial. Our study suggested the a moderate role of CYP4F2 polymorphisms in affecting the pharmacokinetics of Vit E as a therapeutic agent. …”
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49166
Domain structure of the <i>M. circinelloides</i> Ago proteins.
Published 2013“…Arrows indicate the amino acids whose mutations led to a decreased RNA-binding efficiency <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0069283#pone.0069283-Lingel1" target="_blank">[14]</a>. …”
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49167
SPARC has therapeutic potential in severely virus-induced heart failure.
Published 2019“…I EDD were slightly smaller in the SPARC group prior to treatment, compared to the vehicle group, but did not change due to the SPARC treatment, while in the vehicle group EDD were slightly decreased after 72h. ESD were not different between groups or between time-points. …”
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49168
Immunohistochemical staining and scoring analysis of HIC-1 in breast cancer tissues and adjacent normal breast tissue.
Published 2014“…<p>A. HIC-1 protein expression was decreased in breast cancer tissue (400×). …”
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49169
Presentation_1_Restricted Proliferation During Neurogenesis Contributes to Regionalisation of the Amphioxus Nervous System.pdf
Published 2022“…<p>The central nervous system of the cephalochordate amphioxus consists of a dorsal neural tube with an anterior brain. Two decades of gene expression analyses in developing amphioxus embryos have shown that, despite apparent morphological simplicity, the amphioxus neural tube is highly regionalised at the molecular level. …”
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49170
Depurination of <i>Drosophila</i> ribosomes is minimal and does not explain host mortality during parasitic wasp infestation.
Published 2017“…<p>Levels of intact <i>Drosophila</i> ribosomes are not significantly decreased in <i>Spiroplasma</i>-positive flies (blue), compared to <i>Spiroplasma</i>-negative flies (gold) (A,C,E; <i>p</i> = .348, <i>p</i> = .026, <i>p</i> = .693 for <i>L</i>. …”
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49171
Consumption of ultra-processed foods in Brazil: distribution and temporal evolution 2008–2018
Published 2023“…CONCLUSIONS The socioeconomic and demographic segments with the lowest relative consumption of ultra-processed foods in 2017–2018 are precisely those that showed the most significant increase in the temporal analysis, pointing to a trend towards national standardization at a higher level of consumption.…”
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49172
<i>ITP</i> regulates feeding.
Published 2018“…(D) Schematic drawing of the capillary feeding system, which measures the total volume of food eaten during a given period of time. (E) Over-expression of <i>ITP</i> decreases food intake. …”
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49173
Loss of Vps26 in the eye causes PR degeneration.
Published 2014“…<p>(A) Schematic showing the retromer complex associated with an endosomal membrane. …”
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49174
Product acceptability.
Published 2024“…Despite successes in epidemic control at the population level, a concentrated epidemic persists among gay and other men who have sex with men (MSM). …”
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49175
Negative-frequency–dependent selection for <i>lys</i><sup>−</sup><i>orgS</i><sup>−</sup>.
Published 2020“…For each trajectory, we computed the slope of <i>ln</i>(<i>lys</i><sup>−</sup><i>orgS</i><sup>−</sup>/<i>lys</i><sup>−</sup>) over 3 consecutive time points and chose the steepest slope. Since our time unit was generation, we divided this slope (/generation) by <i>ln</i>2/generation and obtained a dimensionless number representing the relative fitness difference between <i>lys</i><sup>−</sup><i>orgS</i><sup>−</sup> and <i>lys</i><sup>−</sup>. …”
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49176
<i>raw</i> and <i>acal</i> act together to counteract JNK signaling.
Published 2015“…(D-E) <i>acal</i> in situ hybridization in <i>raw<sup>2</sup></i> mutants (n = 45; D) and heterozygous siblings (n = 106; E). Arrow in (E) points to decreased <i>acal</i> expression in the lateral epidermis. …”
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49177
Data Sheet 1_GBD: incidence rates and prevalence of anxiety disorders, depression and schizophrenia in countries with different SDI levels, 1990–2021.pdf
Published 2025“…</p>Results<p>In countries with different SDI levels, the age-standardized average annual percentage change (AAPC) in the incidence of anxiety were all shown to be increasing, and there were large gender differences between the different SDI levels, with a maximum of 0.97 (0.76–1.18) for females in countries with a high SDI level, Age-standardized more rates per 100,000 people in high SDI countries, from 658.87 in 1990 to 841.56 in 2021, and the largest gender differences in countries with a low to moderate SDI level, with AAPCs for males and females of 0.04 (0.04–0.05), 0.86 (0.63–1.09); for depression, only the countries with medium-high SDI levels were statistically significant compared to the countries with medium-low SDI levels, with AAPCs of 0.05 (0.04–0.07), 0.04 (0.04–0.05); for schizophrenia in addition to the AAPCs of the countries with medium-high SDI levels showed an increase of 0.16 (0.13–0.18); the rest decreased.…”
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49178
Comparison of the analytical probabilities of tumor progression and the probabilities obtained in simulations.
Published 2024“…Both conditions are especially met by cliques (due to the absence of preexistent drivers in the epistasis network, that leads to relatively small Δ<i>N</i><sub><i>D</i></sub>) with low epistasis factors (that lead to modest decreases in ). Even in those cases, despite the systematic bias in analytical approximations, the analytical expression can distinguish between scenarios of high and low rescue probabilities (only 1.3% of the data points have rescue probability >0.5 in the simulations and <0.5 in the analytical expression or vice versa).…”
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49179
Table_2_Clostridium cellulovorans Proteomic Responses to Butanol Stress.XLSX
Published 2021“…Several additional metabolic adaptations were triggered by butanol exposure such as the up-regulation of V- and F-type ATPases (involved in ATP synthesis/generation of proton motive force), enzymes involved in amino acid (e.g., arginine, lysine, methionine, and branched chain amino acids) biosynthesis and proteins involved in cell envelope re-arrangement (e.g., the products of Clocel_4136, Clocel_4137, Clocel_4144, Clocel_4162 and Clocel_4352, involved in the biosynthesis of saturated fatty acids) and a redistribution of carbon flux through fermentative pathways (acetate and formate yields were increased and decreased, respectively). …”
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49180
Table_1_Clostridium cellulovorans Proteomic Responses to Butanol Stress.DOCX
Published 2021“…Several additional metabolic adaptations were triggered by butanol exposure such as the up-regulation of V- and F-type ATPases (involved in ATP synthesis/generation of proton motive force), enzymes involved in amino acid (e.g., arginine, lysine, methionine, and branched chain amino acids) biosynthesis and proteins involved in cell envelope re-arrangement (e.g., the products of Clocel_4136, Clocel_4137, Clocel_4144, Clocel_4162 and Clocel_4352, involved in the biosynthesis of saturated fatty acids) and a redistribution of carbon flux through fermentative pathways (acetate and formate yields were increased and decreased, respectively). …”