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49641
Two Frizzled Planar Cell Polarity Signals in the <em>Drosophila</em> Wing Are Differentially Organized by the Fat/Dachsous Pathway
Published 2011“…Our results allow us to draw the following conclusions: (1) The Early Fz PCP signals are in opposing directions in the anterior and posterior wing and converge precisely at the site of the L3 wing vein. (2) Increased or decreased expression of Ft/Ds pathway genes can alter the direction of the Early Fz PCP signal without affecting the Late Fz PCP signal. (3) Lowfat, a Ft/Ds pathway regulator, is required for the normal orientation of the Early Fz PCP signal but not the Late Fz PCP signal. (4) At the time of the Early Fz PCP signal there are symmetric gradients of <em>dachsous</em> (<em>ds</em>) expression centered on the L3 wing vein, suggesting Ds activity gradients may orient the Fz signal. (5) Localized knockdown or over-expression of Ft/Ds pathway genes shows that boundaries/gradients of Ft/Ds pathway gene expression can redirect the Early Fz PCP signal specifically. (6) Altering the timing of <em>ds</em> knockdown during wing development can separate the role of the Ft/Ds pathway in wing morphogenesis from its role in Early Fz PCP signaling.…”
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49642
Table_2_Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species.pdf
Published 2022“…<p>The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
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49643
Image_1_Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species.pdf
Published 2022“…<p>The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
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49644
Data Sheet 1_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Age-period-cohort and Joinpoint regression analyses were conducted to identify temporal trends and critical inflection points across SDI quintiles.</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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49645
Table_4_Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species.pdf
Published 2022“…<p>The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
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49646
Table_1_Association Between Ideal Cardiovascular Health and Executive Function in Chinese Primary School Children.DOCX
Published 2022“…</p><p>Results: Compared with children exhibiting 1–3 ideal cardiovascular health metrics, decreases of 1.37–2.63 points (indicating better performance) in metacognition index and its 5 subscale indexes (initiate, working memory, plan/organize, organization of materials, and monitor) were observed in children who attained 5 or 6–7 ideal metrics (all p for trend <0.001). …”
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49647
Table_1_Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species.pdf
Published 2022“…<p>The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
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49648
Data_Sheet_1_Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain.pdf
Published 2020“…Specific involvement of Il-1 (interleukin-1) implicated in the firing of inflammation was observed at P10. This study pointed out age-differences in HI responses kinetics, e.g., a long-lasting inflammatory response at P10 compared to P5. …”
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49649
DataSheet1_Assessment of Fasudil on Contrast-Associated Acute Kidney Injury Using Multiparametric Renal MRI.zip
Published 2022“…<p>Aims: To evaluate the utility of fasudil in a rat model of contrast-associated acute kidney injury (CA-AKI) and explore its underlying mechanism through multiparametric renal magnetic resonance imaging (mpMRI).…”
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49650
Table_1_Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain.xlsx
Published 2020“…Specific involvement of Il-1 (interleukin-1) implicated in the firing of inflammation was observed at P10. This study pointed out age-differences in HI responses kinetics, e.g., a long-lasting inflammatory response at P10 compared to P5. …”
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49651
Santiago and Caballero (2016) theory models the weak selection regime better than classic BGS theory.
Published 2024“…<p>(A) The predicted reduction factor under classic B theory (dark gray line) and the diploid SC16 model (colored lines corresponding to mutation rate) compared to average reduction across 10,000 simulation replicates (points). …”
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49652
Image_5_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.TIF
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49653
Table_3_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49654
Image_4_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.TIF
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49655
Table_5_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49656
Image_8_Cannabinoid WIN55,212-2 reprograms monocytes and macrophages to inhibit LPS-induced inflammation.tif
Published 2023“…Mechanistically, WIN55,212-2 induced a metabolic and epigenetic shift in macrophages by decreasing LPS-induced mTORC1 signaling, commitment to glycolysis and active histone marks in pro-inflammatory cytokine promoters. …”
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49657
Data_Sheet_1_Impact of Citrus Pulp or Inulin on Intestinal Microbiota and Metabolites, Barrier, and Immune Function of Weaned Piglets.pdf
Published 2021“…Inulin (IN), a well-known prebiotic, was used for comparison. …”
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49658
Image_1_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.TIF
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49659
Table_1_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”
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49660
Table_4_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX
Published 2019“…In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. …”