Data Sheet 1_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 4_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Loss-of-function of Mp<i>RTN4IP1L</i> confers resistance to thaxtomin A. by Chloe Casey (14341756)

The schematic diagram of the SD decrease and CNR increase rates by 50% ASiR and MBIR (compared with those by FBP). by Peigang Ning (541890)

“…<p>As the mA value decreased, MBIR brought about gradually augmented variations in the two parameters, whereas 50% ASiR did not give rise to noticeable variations.…”

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. by Mamoru Miyasaka (9187916)

Species that significantly increased (“Winners”) or decreased (“Losers”) in abundance over the past 50+ years in the study area [33]. by Katie Frerker (680803)

“…</p><p>Species that significantly increased (“Winners”) or decreased (“Losers”) in abundance over the past 50+ years in the study area <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0115843#pone.0115843-Wiegmann1" target="_blank">[33]</a>.…”

K-means++ clustering algorithm. by Zhen Zhao (159931)

“…Firstly, recursive feature elimination using cross validation (RFECV), maximum information coefficient (MIC), and mean decrease accuracy (MDA) methods were utilized to select population distribution feature factors. …”

SDG decreases p70S6K1 and increases AMPK protein expression in iron treated H9c2 cells. by Stephanie Puukila (568109)

Non-response analysis. by Sebastian Starystach (8493531)

Bubble plot showing the dose–response relationship between the mean volume (A) and Intensity (B) of exercise intervention and effect size changes for Hcy plasma levels (%) for the... by Rafael Deminice (3177675)

Inhibition of TMEM16A decreased SW620 cell migration and invasion. by Yujie Sui (549090)

Data_Sheet_1_Decreased Cerebral Amyloid-β Depositions in Patients With a Lifetime History of Major Depression With Suspected Non-Alzheimer Pathophysiology.pdf by Kuan-Yi Wu (566485)

Serum samples and 50% NAI values. Serum samples taken from CEIRS study. by Harrison Powell (9040128)

Decreased levels of glycosylated α-DG and laminin levels distal to the glial dome in <i>POMGnT1</i>-KO and <i>Large</i>^{<i>myd/myd</i>} mice. by Shigefumi Morioka (8893511)

Fig 3 - by Rafael Alves Guimarães (4526788)

Kat60 lacking the MIT domain does not disassemble microtubules at low levels of accumulation in cells. by Kyle D. Grode (725568)

Kat60 lacking the MIT domain disassembles microtubules at high levels of accumulation in cells. by Kyle D. Grode (725568)

Inducible expression of Kat60 results in measurable microtubule disassembly in our single-cell assay. by Kyle D. Grode (725568)

PNs, ORNs and LNs response to a short (50 ms) pulse, similar results of Fig 4. by Mario Pannunzi (553941)

Praziquantel treatment does not alter SmLy6A and SmLy6B IgG₁ age distribution profiles, but does decrease antigen-specific IgG₁ reactivity. by Iain W. Chalmers (173561)