Adverse effect of ND251 aggregates on neurite outgrowth. by Huei-Ying Li (210957)

“…Cells expressing ND251S5A had a further decrease in the percentage of neurite-bearing cells in comparison with ND251. …”

NAP1-Assisted Nucleosome Assembly on DNA Measured in Real Time by Single-Molecule Magnetic Tweezers by Rifka Vlijm (133750)

“…We observe a decrease in end-to-end length when NAP1 and core histones (CH) are added to the dsDNA. …”

FSM^R GAPDH variants support robust catalytic efficiency but exhibit altered cooperativity. by Andrew J. Jezewski (8934521)

“…A statistically significant decrease in catalytic efficiency is measured for the GAPDH^V238A variant compared to WT. …”

The extent of axonal pathology peaks six months after the onset of EAE in MP4-immunized B6 mice. by Johanna Prinz (836737)

“…The numbers and percentages of axons showing mitochondrial swelling (A, B), a decreased NNND (F, G) or complete axolysis (K, L) were evaluated. …”

Amphotericin-B and vancomycin-loaded chitosan nanofiber for antifungal and antibacterial application by Soroush Karimi (7367183)

“…<div><p>In the present study, a mucoadhesive non-woven fiber mat (d= 116 nm) was fabricated by the electrospinning method using chitosan (80% Wt), polyethylene oxide (10% Wt), cysteine (4% Wt) and drugs (6% Wt), respectively. …”

Impact of Dsg2 on invasion. by Wiebke K. Peitsch (173727)

“…<p>(A, B) Transwell invasion assays of Dsg2-depleted (“Dsg2 Ko”) or non-targeting siRNA-treated (“nt Ko”) MeWo and C32. …”

Inhibitors of Cl⁻ channels differently affect OGD-induced swelling in HR-and LR-astrocytes. by Jana Benesova (155548)

“…<p>The effect of 100 µM NPPB, a non-specific inhibitor of chloride channels (<b>A</b>), 30 µM Tamoxifen (<b>B</b>) and 30 µM DCPIB (<b>C</b>), inhibitors of volume regulated anion channels. …”

Mechanisms underlying the therapeutic potential of time-restricted eating in Huntington’s disease. by Russell G. Wells (20933789)

“…<p>Time-restricted eating (TRE), a form of intermittent fasting, in animal models of Huntington’s disease (HD) and non-HD human and animal studies reveal that the practice increases autophagic activity which is thought to decrease aggregation of the mutant huntingtin protein (mHtt), stimulates production of brain derived neurotrophic factor (BDNF), improves metabolic functions, promotes oxidative stress resistance and decreases reactive oxygen species (ROS), and improves measures of circadian rhythm function. …”

Confocal microscopy study of the binding of Bid and caspase-8 to giant unilamellar vesicles containing cardiolipin. by Olivier Jalmar (283659)

“…The arrows indicate the decrease in GUV fluorescence following the formation of a complex between procaspase-8 and Bid_Alexa488, resulting in a non-fluorescent tBid.…”

DataSheet_1_Exploiting the resource-ratio (R*) hypothesis for weed management in legume crops: An example of volunteer Brassica napus in soybean.docx by Charles M. Geddes (14016552)

“…Merr.], in the presence of four different populations of an interfering non-leguminous weed, volunteer canola (Brassica napus L.), compared with a weed-free control. …”

Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_3_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

CSN acts in neurons via Cullin1 or Cullin3. by Inna Djagaeva (369627)

“…<p>(A) PNS neurons in a non-mutant third instar larva, visualized by the <i>109(2)80-GAL4</i>-driven expression of <i>UAS-GFP</i>. …”

Optical imaging of luminescence for quantification of gene electrotransfer in mouse muscle and knee-1 by C Bloquel (56006)

“…For all experiments, the first measurement was performed 2 minutes after luciferin injection. Panel A: luciferin injection (2.5 mg/250 μl), n = 5 Panel B: local luciferin injection into the muscle (100 μg/40 μl) and into the knee joint (50 μg/10 μl), n= 5/organ. …”

Expansion models of the CTG repeat expansion in blood and saliva. by Eyleen Corrales (6659279)

AZ2.0 Scripts & Code by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the percentage repeat, over the earlier assembly (v1.0). …”