Table_1_Oleanolic Acid Mitigates 6-Hydroxydopamine Neurotoxicity by Attenuating Intracellular ROS in PC12 Cells and Striatal Microglial Activation in Rat Brains.DOCX by Zama N. P. Msibi (7292738)

“…This finding was in correlation with significantly improved motor symptoms and increased striatal dopamine in treated rats as compared to non-treated rats. Flow cytometry assessment of PC12 cells revealed a decreased amount of intracellular ROS in cells pre-treated with OA 6 h prior to 6-OHDA exposure and cells treated with OA 1 h post 6-OHDA exposure, suggesting that OA provides neuroprotection in PC12 cells by removing intracellular ROS, thereby reducing oxidative stress. …”

image4_Artocarpus tonkinensis Extract Inhibits LPS-Triggered Inflammation Markers and Suppresses RANKL-Induced Osteoclastogenesis in RAW264.7.jpeg by Elena Orecchini (8585280)

“…<p>Artocarpus tonkinensis (At) leaf decoction, a traditional remedy prepared in North Vietnam by the Hmong ethnic group, is a tea extract rich in bioactive compounds that may have therapeutic effects in arthritis and backache. …”

Impaired osteoclastogenesis in Cx43cKO fractures. by Alayna E. Loiselle (151690)

“…Cx43cKO fractures have significantly decreased Osteoclast number and Osteoclast surface at 28 days relative to WT. (*) indicates p<0.05 between groups at a given time-point, n=4 specimens/genotype/ time-point. …”

Ellagic Acid Derivatives from <em>Terminalia chebula</em> Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate <em>Pseudomonas aeruginosa</em> PAO1 Virulence by Sajal Sarabhai (104656)

“…<em>C. elegans</em> fed on F7-treated <em>P. aeruginosa</em> showed enhanced survival with LT50 increasing from 24 to 72 h. LC-ESI-MS of F7 revealed the presence of ellagic acid derivatives responsible for anti QS activity in <em>T. chebula</em> extract.…”

Soluble HLA-DR alpha 2 domain inhibits IFN-γ cytokine expression and phosphorylation of STAT4, but not STAT6. by Grit-Carsta Bulwin (75307)

“…In the presence of sHLA-DRα2 (50 µg/ml) the phosphorylation of TCR-ζ chain and ZAP70 in stimulated cells (right lane) was reduced to a level similar to that of non-stimulated cells (left lane) while in stimulated cells without sHLA-DRα2 (middle lane) substantial phosphorylation of both proteins was observed.…”

miRNA Signature of Mouse Helper T Cell Hyper-Proliferation by Connie L. Sommers (426576)

“…This mutation leads to a number of changes in T cells that result in altered cytokine production including increased IL-4 production, increased proliferation, and decreased apoptosis. …”

Cx43 immunostaining and quantitative analysis in the neuromuscular compartment of normal and diverticular disease human colon. by Letizia Mattii (302997)

“…<p>In normal colon, appreciable amounts of Cx43 are expressed in the circular (CM) and longitudinal muscle (LM) (A), while Cx43 expression is decreased in samples from DD colon (B); scale bar: 100 µm. …”

Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells by Bolun Wang (1465285)

Egg size, offspring size, and offspring survival in the two environments (Experiment 3). by Thomas Tully (53900)

“…Non randomness in the residuals is evidenced by a local polynomial regression fit (curves, computed using <i>scatter.smooth</i> function in software R 2.1). …”

Table_1_Antimicrobial Activity of Nanoconjugated Glycopeptide Antibiotics and Their Effect on Staphylococcus aureus Biofilm.DOCX by Francesca Berini (3703174)

“…IONPs can direct conjugated antibiotics to infection sites by the use of an external magnet, facilitating tissue penetration and disturbing biofilm formation. As a consequence of antibiotic localization, a decrease in its administration dosage might be possible, reducing the side effects to non-targeted organs and the risk of antibiotic resistance spread in the commensal microbiota. …”

<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b> by Bettina Mittendorfer (88840)

“…<a href="" target="_blank"> Total postprandial glucose appearance rate was lower after compared with before weight loss in both the BDT and RYGB groups because of a decrease in endogenous glucose production, without a difference between groups. …”

The Conserved Lid Tryptophan, W211, Potentiates Thermostability and Thermoactivity in Bacterial Thermoalkalophilic Lipases by Emel Timucin (503760)

“…Further thermoactivity and CD spectroscopy analyses showed that W211A also led to a strong decrease in the optimal and the melting temperature of BTL2, implying stabilization by W211 also to the intramolecular interactions. …”

Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity by Wayne Chadwick (165106)

“…Amitriptyline treatment also caused a significant potentiation of non-toxic Aβ monomer with a concomitant decrease in cytotoxic dimer Aβ load, compared to vehicle-treated 3×TgAD controls. …”

Description of research subjects. by Tulus Winarsunu (16324693)

“…There is a decrease in hopelessness and an increase in internal locus of control in people with DM given hope therapy.…”

Results from experiment 3, 4 and 5. by Olivia Carter (194606)

“…The 2^nd and 3^rd column show a clear decrease in the strength and location specificity of perceptual bias as the target speed slows down to 20 and 100sec per loop. …”

Transcriptomic and epigenomic effects of insoluble particles on J774 macrophages by T. Emi (9586434)

“…We hypothesized that especially the insoluble, non-digestible particles that do not release a known hazardous chemical can be underappreciated agents acting to affect the regulation inside macrophages upon phagocytosis. …”

Intrapericardial Delivery of Gelfoam Enables the Targeted Delivery of Periostin Peptide after Myocardial Infarction by Inducing Fibrin Clot Formation by Brian D. Polizzotti (166489)

“…Intrapericardial administration of drug-eluting hydrogels may provide a clinically viable strategy for increasing myocardial retention, therapeutic efficacy, and bioactivity of rPN and to decrease systemic re-circulation.…”

Microfluidic Low-Input Fluidized-Bed Enabled ChIP-seq Device for Automated and Parallel Analysis of Histone Modifications by Travis W. Murphy (5352482)

“…Progress has been made to decrease the input required by gold-standard genome-wide profiling tools like chromatin immunoprecipitation followed by sequencing (i.e., ChIP-seq) to allow scarce primary tissues of a specific type from patients and lab animals to be tested. …”

Tissular and cellular effects of simulated UV daylight on human reconstructed skin. by Claire Marionnet (244033)

“…<p>(a): DUVR spectrum was recorded with a calibrated Macam spectroradiometer. …”

Investigation of Encephalopathy Caused by Shiga Toxin 2c-Producing <em>Escherichia coli</em> Infection in Mice by Muhammad Yunus Amran (388687)

“…Astrocytes (ASTs) were activated in the medulla oblongata and spinal cord, and a decrease in aquaporin 4 around the ECs suggested that BBB integrity was compromised directly by Stx2c or through the activation of ASTs. …”