Image_5_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…Additionally, a more than 2-fold increase in secreted Aβ_1−x was observed under the latter two conditions. …”

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Jun Ding (80820)

“…Both homoplasmies and heteroplasmies show 5-fold higher transition/transversion ratios than variants in nuclear DNA. …”

Refeeding leads to enhancer overshoot with increased LXR footprint and enrichment of the LXR motif. by Noga Korenfeld (19557350)

“…FA, flanking accessibility; FC, fold change; FPD, footprint depth; LXR, liver X receptor; TF, transcription factor.…”

Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation by Bhavapriya Vaitheesvaran (177385)

DepMap essential genes exhibit preferential epigenetic conservation. by Daniel Rud (11432670)

“…<b>C)</b> DepMap essential genes (shRNA log-fold decrease less than -0.4) showed significantly smaller gene PWDs than non-essential genes. …”

KChIP2 KD associates with a relocalization of presenilin 1 away from sarcomeric structures. by Drew M. Nassal (845780)

“…<b>(D)</b> Representative immunostaining for RyR between Ad.GFP (left panel) and Ad.KChIP2 KD (right panel), showing preserved distribution. <b>(E)</b> Average plot profile for presenilin 1 from regions of interest (white boxes) showing the decreased peak intensity at sarcomeres and increased intensity between sarcomeres in Ad.KChIP2 KD (n = 25) compared to Ad.GFP (n = 25) myocytes. …”

HP1a protein levels are reduced and its localization pattern is altered by over-expression of CHD1. by Lakshmi Bugga (393594)

Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals by Hanna Shin (6697529)

Comparative growth rates of cultured marine dinoflagellates in the genus <i>Symbiodinium</i> and the effects of temperature and light by Anke Klueter (365228)

Impact of precipitation and temperature changes on hydrological responses of small-scale catchments in the Ethiopian Highlands by Tatenda Lemann (3187935)

“…Results indicate that runoff reacts disproportionately strongly to precipitation and temperature changes: a 24% increase in precipitation led to a 50% increase in average annual runoff, and an average annual rainfall–runoff ratio that was 20% higher. …”

Synaptic weights are optimal with respect to output noise. by John Porrill (35799)

“…<p>Here the plant suffers a 50% decrease in gain and learning takes place in 4 PFs carrying levels <i>α</i>_i = 1, 1, 2, and 2 of the same unit power signal <i>s</i> and levels <i>σ</i>_i = 1/2, 1, 1/2, and 1 of independent noise (see legend below for [A]). …”

NF-κB regulation of mesodermal and neural markers: by Chi Zhang (9857)

“…G: Treatment of early embryos with AKBA (50 µM from the 4-cell stage on) lead to a decrease in <i>Xbra</i> staining (control and AKBA-treated embryos marked). …”

Effects of resistance exercise versus combined training on post-exercise hypotension in women with metabolic syndrome by Ramires Alsamir Tibana (8977688)

“…Therefore, RE and COMB elicited post-exercise hypotension in women with MS; COMB provided a greater decrease which may be of value in the prevention and treatment of cardiovascular disorders.…”

Data Sheet 2_An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences... by Andrew Yung Fong Li Yim (22058717)

“…Response was defined as ≥3 drop in Simple Endoscopic Score for Crohn’s Disease (SES-CD) in combination with a ≥50% reduction in C-reactive protein (CRP) and fecal calprotectin and/or a ≥3 point drop in Harvey-Bradshaw Index (HBI). …”

Data Sheet 1_An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences... by Andrew Yung Fong Li Yim (22058717)

“…Response was defined as ≥3 drop in Simple Endoscopic Score for Crohn’s Disease (SES-CD) in combination with a ≥50% reduction in C-reactive protein (CRP) and fecal calprotectin and/or a ≥3 point drop in Harvey-Bradshaw Index (HBI). …”

Differential OTU abundance of anode-attached microbes and reactor microbes between M1L and M2L reactors. by Nattawet Sriwichai (18847466)

“…<b>E</b>, Bar chart represents the fold-change of 7 OTUs with decreased abundance in M1L. …”

Differential OTU abundance of anode-attached microbes and reactor microbes between M1L and M2H reactors. by Nattawet Sriwichai (18847466)

“…<b>E</b>, Bar chart represents the fold-change of 30 OTUs with increased abundance in M1L. …”

Effects of TTP2515 on metabolic and calorimetry parameters in leptin-deficient mice. by Roxanne Dutia (418714)

“…(<b>C</b>) Body weight was significantly lower in TTP2515-treated mice on the 50 mg/kg dose. (<b>D</b>) Immediately upon starting the 50 mg/kg dose, mean respiratory quotient was significantly decreased in TTP2515 treated mice during the light cycle. …”

Table 3_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Conversely, natural killer (NK) cells eQector function is enhanced in the absence of HLA, making NK cellular therapies an attractive option for ICI resistant tumors. …”

Table 7_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Conversely, natural killer (NK) cells eQector function is enhanced in the absence of HLA, making NK cellular therapies an attractive option for ICI resistant tumors. …”