An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers by Moran Elishmereni (203218)

“…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”

Table_2_Multiple Ecological Parameters Affect Living Benthic Foraminifera in the River-Influenced West-Central Bay of Bengal.docx by Thejasino Suokhrie (10717653)

Image_1_Odorant-Binding Proteins Contribute to the Defense of the Red Flour Beetle, Tribolium castaneum, Against Essential Oil of Artemisia vulgaris.JPEG by Yuan-chen Zhang (9321452)

Table_1_Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson’s Disease Pathology.DOCX by Anna Wilkaniec (4737126)

Image2.TIF by Anna Kovalchuk (4864324)

Effect of GA₃ Treatment on Seed Development and Seed-Related Gene Expression in Grape by Chenxia Cheng (479968)

Table_1_Odorant-Binding Proteins Contribute to the Defense of the Red Flour Beetle, Tribolium castaneum, Against Essential Oil of Artemisia vulgaris.docx by Yuan-chen Zhang (9321452)

<b>Genome assembly at chromosome level and evolutionary analysis of </b><i><b>Coregonus ussurinsis</b></i><b> Berg</b> by Tianqing Huang (9743483)

“…The sequence length was 2,627.19 Mb with a contig N50 length of 4.27 Mb. Then 3,109 contigs were assembled into scaffolds, resulting in a genome assembly with 40 chromosomes and a scaffold N50 length of 62.20 Mb, and the size of the genome was 2.51 Gb, and the integrity was more than 95% by BUSCO test. …”

Maternal Nutrient Restriction Alters Ca²⁺ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats by Thomas J. Harvey (800460)

microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model by Fu Jia Liu (422650)

Data_Sheet_1_Antibacterial activity and mechanism of Stevia extract against antibiotic-resistant Escherichia coli by interfering with the permeability of the cell wall and the memb... by Xu Chen (432759)

Table_2_Odorant-Binding Proteins Contribute to the Defense of the Red Flour Beetle, Tribolium castaneum, Against Essential Oil of Artemisia vulgaris.docx by Yuan-chen Zhang (9321452)

Conceptual summary of GRS effects across studies. by Marco K. Wittmann (14710470)

Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp. by Laura C. Laurella (469416)

“…<div><p>Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of <i>Mikania variifolia</i> and <i>Mikania micrantha</i> dichloromethane extracts. …”

Sensitivity analysis of model simulated [PGE2] in wild type MEF cells at 48 hours post radiation. by Chad Liu (584132)

“…The dashed line indicates the level where the fold change was equal to unity, i.e., no change in [PGE2].…”

Early Wnt/β-catenin signaling enhances cardiac differentiation. by Sharon L. Paige (247316)

The F2-isoprostane approach allows for analysis of FOXO transcription factor control of endogenous oxidative stress. by Christiaan F. Labuschagne (485155)

“…DLD-1 and DL-23 cells were incubated with 4-OHT to activate FOXO3a for 24 hours, before treatment with PQ for another 8 hours. 5-iPF2α-VI levels were analyzed and data are represented as mean fold increase ± S.E.M (*p < 0.05, *** p < 0.001).…”

C-I TF screen quantitative phenotypic analyses. by Eswar Prasad R. Iyer (177455)

“…The direction of arrow represents increase (up), decrease (down) or no change (hyphen). Size bar corresponds to 50 microns.…”

Analysis of drug delivery using the Microformulator. by Dharaminder Singh (12646624)

(Color online) Sketch of the model. by Paula Villa Martín (3220506)

“…For instance, a point close to vertex <i>T</i>¹ exploits better the limiting resource 1 (e.g. soil nutrients) than another one near vertex <i>T</i>², but is less efficient at exploiting resource 2 (e.g. light) than this latter one (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005139#sec014" target="_blank">Methods</a>). …”