Locomotor response to CNO under normal conditions. by Hailong Li (216327)

“…The mean number of total ambulations (± SEM) did not significantly change as a function of CNO dose, indicating that the administered doses of CNO did not elicit unforeseen locomotor effects. …”

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 <i>In Vitro</i> by Daniel M. DeLaughter (3140697)

Fold change in Asn, Asp, Gln and Glu of pepper leaves after different treatments (high aphid density, low aphid density, and water stress). by Victoria Florencio-Ortiz (5329202)

Fold change in total FAA, EAA and NEAA of pepper leaves after different treatments (high aphid density, low aphid density, and water stress). by Victoria Florencio-Ortiz (5329202)

Fold change in Ala, Ser, Thr and His of pepper leaves after different treatments (high aphid density, low aphid density, and water stress). by Victoria Florencio-Ortiz (5329202)

Collagen type I monomers increase Phospho-Akt expression via PI3kinase activation. by Mirjam Stahl (487952)

“…Basal, constitutive phospho-Akt expression was high in AM from each 5 healthy donors and IPF patients. A non-selective inhibitor of PI3kinase, LY294002 (50 μM, DMSO as control), abrogated CCL18 production following stimulation with collagen type I monomers and decreased significantly spontaneous CCL18 production of AM (Panel <b>B</b>). …”

Sod3 protects <i>Histoplasma</i> yeasts from ROS produced by activated macrophages. by Brian H. Youseff (164159)

“…<p>(<b>A–B</b>) Survival of yeasts after infection of resting (<b>A</b>) or cytokine-activated (<b>B</b>) murine macrophages. …”

The complementary chimera IIS4I shifts the gating of Ca_V1.2 channels towards low-voltage behavior. by Ana Laura Sanchez-Sandoval (4885423)

“…Data in graphs represent mean ± SEM. Parameter values, number of cells and statistical significance are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0193490#pone.0193490.t001" target="_blank">Table 1</a>. …”

Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf by Toru Suzuki (512729)

“…There was no significant change in hemoglobin A1c level over time. FLI (mean ± standard deviation: 68.1 ± 21.9 vs. 39.6 ± 25.0, P < 0.001), but not FIB-4 index as a marker of hepatic fibrosis (median [interquartile range]: 1.04 [0.78-1.39] vs. 1.01 [0.68-1.36], P = 0.909), was significantly decreased by treatment with pemafibrate for 12M, and the proportion of patients with metabolic dysfunction-associated SLD (MASLD) was significantly decreased from 92.3% (baseline) to 61.5% (12M).…”

Qualitative and quantitative assessment of manually re-evaluated genomes. by Abhinay Ramaprasad (521263)

“…Repetitive domains were omitted and the copy with the lowest e-value score is used for comparison. A 10-fold change in the e-value was considered as a significant change. …”

Loss-of-function mutant of Mp<i>LOS1</i> displays defects in meristem maintenance. by Satoshi Naramoto (6178970)

“…<i>p-</i>Values lower than 0.01 were indicated by asterisks (*). (E-G) Cell division activities in Mp<i>los1-1</i> mutants decreased after 3 days’ incubation. …”

Mutation of the hydrophobic tip residues disrupts evoked transmitter release. by Matthew R. Bowers (8423115)

“…<p>The single hydrophobic mutation decreased neurotransmitter release by 50% while the double mutation inhibited release to a greater extent than that seen in <i>syt^null</i> mutants. …”

Comparison of whole genome prediction accuracy across generations using parametric and semi parametric methods by Abbas Atefi (10414497)

“…The genome comprised one chromosome of 100 cM length carrying 50 QTLs. There was no significant difference between accuracy of investigated methods (p > 0.05) but among three methods, the highest mean accuracy (0.659) was observed for BayesA. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”

Biochar particle size, shape, and porosity act together to influence soil water properties - Fig 4 by Zuolin Liu (633898)

“…<p>Negative Pearson correlation coefficients (<i>R</i>) between bulk density (<i>ρ</i>_<i>b</i>) and (a) initial water content (<i>θ</i>_<i>i</i>), (b) field capacity (<i>θ</i>_<i>fc</i>), (c) permanent wilting point (<i>θ</i>_<i>pwp</i>), (d) plant available water (<i>θ</i>_<i>paw</i>) and positive <i>R</i> between total porosity (<i>ϕ</i>_<i>T</i>) and (e) initial water content, (f) filed capacity, (g) permanent wilting point, (h) plant available water showed that soil water retention decreased with <i>ρ</i>_<i>b</i> increase but increased with <i>ϕ</i>_<i>T</i> increase.…”

Histological analysis of the calluses. by Tero Puolakkainen (4247116)

“…Black arrows pinpoint newly formed trabeculae. At the two week time point, ActRIIB-Fc treatment caused increased (E) woven bone volume and (F) cartilage volume compared to PBS controls resulting in increased (G) mineralized tissue per tissue volume. …”

Relative mRNA abundance of nine target genes after injecting siRNAs. by Hang Li (123039)

“…The mRNA levels of target genes in the siRNA-treated group were relative to the negative control group at the same time point. Error bars indicate standard errors. Statistical significance of differences were analyzed with student T-test (decreasing significance,* P<0.05, **P<0.01; increasing significance, # P<0.05 ).…”

Absence of excision repair of CPDs in telomeres. by Patrick J. Rochette (249729)