Effect of rPVH1-yCD/5FC treatment on NFκB and Akt/PI3K activity. by Soukaina Réjiba (445416)

“…<b>E</b>) NFκB and Akt/PI3K inhibitors (MG132, LY294002) combination enhances the cytopathic effects induced by wtPV-H1 and rPVH1-yCD/5-FC. …”

A purification strategy employing secNluc-FLAG fusion proteins and anti-FLAG magnetic beads for optimizing the application of secNluc reporter system. by JingZhe Li (5166095)

“…Because of the extensive dilution multiple, Logarithmic calculation was employed in order to decrease the drift degree of data. In (B) to (J), the data shown are the means ± standard errors of three independent experiments.…”

Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[<i>c</i>]phenanthrene and Its Metabolites:  Synthesis, Physical, and Biological Properties by Mahesh K. Lakshman (1554784)

Rhesus macaque CD4 alleles are universally defective for HIV-1 entry. by Cody J. Warren (563898)

“…Values above error bars represent fold decrease relative to human CD4 for those samples that passed significance thresholds (one-way ANOVA for repeated measures effect, Dunnett’s test; <i>P</i> < 0.05). …”

Proteomic and phosphoproteomic time course over sexual differentiation. by Melvin Bérard (7907558)

“…Details of all sites can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002963#pbio.3002963.s008" target="_blank">S1</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002963#pbio.3002963.s009" target="_blank">S2</a> Tables and on <a href="https://pombephosphoproteomics.unige.ch/" target="_blank">https://pombephosphoproteomics.unige.ch/</a>. (<b>D</b>) Fold enrichment for TORC, TORC1, TORC2, Orb6, and Cdc2 substrates among phosphosites that change (gray), decrease (blue) or increase (red) in abundance during starvation (top) and mating (bottom). …”

Hypoxia upregulates ALKBH5 <i>via</i> HIF-1α. by Armin Thalhammer (233088)

“…<p>(<b>A</b>) Hypoxic induction of <i>ALKBH1-8</i> in MCF7, U2OS and IMR32 cells. Values are the fold increase in mRNA in cells cultured for 16 hours in hypoxia (1.0% oxygen) relative to parallel cultures in normoxia (21% oxygen). …”

Dying and surviving neurons have distinctive gene expression signatures in rat hippocampus. by Daniel R. Rojo (104661)

<i>In vivo</i> blocking of ICG-Glu-Glu-AE105 by uPA, the natural ligand. by Karina Juhl (2144860)

“…In all timepoints the two groups were significantly different with the group receiving only ICG-Glu-Glu-E105 having a 2 fold higher signal.</p>…”

Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry by Sylvia Haas (414005)

“…The proportion of patients with TTR≥65% varied from 16.7% in Asia to 49.4% in Europe. There was a 2.6-fold increase in the risk of stroke/SE, 1.5-fold increase in the risk of major bleeding, and 2.4-fold increase in the risk of all-cause mortality with TTR<65% versus ≥65% after adjusting for potential confounders. …”

File S1 - A Genetically Encoded Reporter for Real-Time Imaging of Cofilin-Actin Rods in Living Neurons by Jianjie Mi (504427)

Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry by Sylvia Haas (414005)

“…The proportion of patients with TTR≥65% varied from 16.7% in Asia to 49.4% in Europe. There was a 2.6-fold increase in the risk of stroke/SE, 1.5-fold increase in the risk of major bleeding, and 2.4-fold increase in the risk of all-cause mortality with TTR<65% versus ≥65% after adjusting for potential confounders. …”

Model of cdr2 action in mitosis. by Kevin J. O'Donovan (250670)

“…<p>Cdr2 levels increase in G2, peak in mitosis and decrease as cells exit mitosis. Nuclear envelope breakdown in prometaphase allows newly synthesized cdr2 access to c-myc protein, which, like other transcription factors <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010045#pone.0010045-Delcuve1" target="_blank">[61]</a>, partitions itself off DNA during chromatin condensation, coinciding with mitotic shutdown of transcription. …”

Model architecture and dynamics. by Kai Ueltzhöffer (754206)

“…Trajectories (red) started at an arbitrary point explore the phase space, due to the noise, but tend to stay close to one of the attractors, due to the deterministic dynamics. …”

Shape rescue in the midface phenotype in the Dp(16)1Yey/ <i>Ripply3</i>^<i>tm1b</i> compound mutant. by José Tomás Ahumada Saavedra (22290934)

“…On the left, the histogram of every point distance evaluated (in this case, more than 1.238.684 points) and the surface differences with the color code for the increase-decrease dimensions (Red to green).…”

<i>FoxD(RNAi)</i> animals display abnormal anterior pole, head patterning and midline gene expression. by M. Lucila Scimone (508003)

“…<p>(<b>A</b>) Upper panels: animals injected with <i>FoxD</i> dsRNA regenerated normally sized anterior blastemas with one eye (73/130) or smaller blastemas with no eyes (24/130) seven days following amputation. …”

Effect of probenecid on biopterin levels in the blood and urine after 6RBH₄ administration. by Akiko Ohashi (3202062)

“…“BH₄ + Pbc” (Student’s <i>t</i>-test), <i>P</i> = 0.03 at 30 min; <i>P</i> = 0.006 at 120 min; <i>P</i> = 0.02 at 180 min. 3) “BH₄ alone”, decreased (Paired <i>t</i>-test), 0-time <i>vs</i>. each data point from 60–300 min, <i>P</i><0.05. 4) “BH₄ + Pbc”, decreased (Paired <i>t</i>-test), 0-time <i>vs</i>. each data point from 30–300 min, <i>P</i><0.003. 5) “BH₄ alone” <i>vs</i>. …”

Differences in spinal excitability across the three pre-movement phases. by Michael J. Asmussen (399456)

“…<p>Group-averaged spinal excitability data (with standard error of the mean) for each pre-movement time point (i.e., PW1, PW2, PG) and muscle (FDI, ADM). …”

Evaluation of prevalence, biochemical profile, and drugs associated with chronic kidney disease-mineral and bone disorder in 11 dialysis centers by Rodrigo Reis Abrita (5187437)

“…The comparison between the groups showed that the level of iPTH decreased with increasing age. Diabetic patients had a higher prevalence of iPTH < 150 pg/mL (27.6%). …”

Image_4_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.tif by Csilla Fazakas (218764)

Citrullinated proteins are present in the lactating mammary gland and are citrullinated, in part, by PAD3. by Guangyuan Li (6490)