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19941
Synaptic transmission at cortico-LA synapses is affected by the absence of αGDI.
Published 2012“…(<b>C<sub>2</sub></b>) For each stimulation intensity a ∼60% decrease of EPSC size is observed in <i>Gdi1</i>-null mice. …”
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19942
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19943
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19944
Gene expression of chemokines and their receptors after spinal cord injury (SCI).
Published 2020“…All data are expressed the relative level (fold) to compare with pod 0 (basal level) after normalization against <i>Gapdh</i> as a housekeeping gene (n = 6 mouse at each time-point). …”
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19945
Starvation-Associated Genome Restructuring Can Lead to Reproductive Isolation in Yeast
Published 2013“…By contrast, the frequency of point mutations is less than 2-fold greater. In a particular case, we observe that a starved lineage becomes reproductively isolated as a direct result of the stress-related accumulation of a single chromosome. …”
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19946
Jhdm1a regulates the expression of C/EBPα, thereby indirectly modulating gluconeogenic gene expression.
Published 2012“…C/EBPα mRNA level and protein level were shown from independent groups of mice. **, P<0.02. (F) Decreased C/EBPα expression in the liver of <i>ob/ob</i> mice (n = 5 per group) ectopically expressing wild-type Jhdm1a, but not in the liver expressing H212A point mutant. ***, P<0.001. …”
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19947
CreA maintains fungal bioenergetics homeostasis.
Published 2017“…Metabolites that are boxed in red and green are significantly increased and decreased, respectively, in Δ<i>creA</i>, and black are not significantly changed (p≤0.05 by Welch’s two-sample t-test). mRNA levels of key metabolic enzymes are given as fold-change in Δ<i>creA</i> compared to wild type. …”
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19948
Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice
Published 2014“…The sub-50 nm size TBG nanocapsule (s50-TBG) is a slightly negatively charged, uniform particle of 15 - 20 nm size which confers protection to the nucleic acid cargo. …”
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19949
Incorporation of 8-oxo-dG, but not 5-OH-dC, reduces the Tm of ASO:DNA and ASO:RNA duplexes.
Published 2015“…<p><b>(A)</b> Structures of 8-oxo-dG, its zwitterionic (minor) form and 5-OH-dC (common and minor forms). …”
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19950
Hypoxia-induced pulmonary remodeling.
Published 2024“…Group1 mice showed a significant decrease in normal but increase in fully remodeled arterial walls. …”
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19951
Heatmaps on Regulatory Effect of Topological Domain Size.
Published 2025“…We plot the log2 fold change in the expression rate in response to <b>(A)</b> reducing the barrier distances from 10 kb to 1 kb, <b>(B)</b> reducing nonspecific topoisomerase activities 10-fold, <b>(C)</b> reducing the barrier distances from 10 kb to 1 kb and increasing topoisomerase nonspecific activities 10-fold to compensate, <b>(D)</b> increasing the barrier distances from 10 kb to 100 kb, <b>(E)</b> increasing the nonspecific topoisomerase activities 10-fold, and <b>(F)</b> increasing the barrier distances from 10 kb to 100 kb and decreasing the nonspecific topoisomerase activities 10-fold to compensate.…”
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19952
Determination of malvidin-3,5-diglucoside content in wines from Cabernet Cortis and three Italian-resistant hybrids, with preliminary evaluation of oenological glycosidases for enz...
Published 2024“…Malvin content exceeded the limit of 15 mg/L, imposed by the Italian government for the commercialization of wines, in 18 out of 21 samples and showed a significant decrease during wine ageing (by about 40–50% every 12-month period) with the scarce effect of maceration time and fermentation temperature. …”
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19953
Image_2_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF
Published 2021“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”
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19954
Image_1_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF
Published 2021“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”
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19955
Image_3_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF
Published 2021“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”
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19956
16S rRNA gene profiling and genome reconstruction reveal community metabolic interactions and prebiotic potential of medicinal herbs used in neurodegenerative disease and as nootro...
Published 2019“…These values were log<sub>10</sub> transformed and depicted in the heatmap. E. Taxa displaying low herb responsiveness. Taxa displaying decreased average abundance >5-fold compared to controls in all herb-supplemented cultures. …”
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19957
CAR undergoes RIP by the γ-secretase complex.
Published 2013“…Drug treatments resulted in accumulation of CAR CTF1 (20 kDa) and a decrease in CAR CTF2 (14 kDa) levels in a dose-dependent manner. …”
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19958
TTP is involved in Otud-6b mRNA rapid degradation after induction.
Published 2011“…The qRT-PCR was performed to detect Otud-6b mRNA remaining at each time point. <b>E.</b> Semi-quantitative RT-PCR analysis of Otud-6b mRNA remaining at each time point after Act.D adding. …”
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19959
Blockade of GKAP degradation prevents Aβ-induced actin cytoskeleton remodeling.
Published 2011“…Rat frontal cortical neurons were transfected with either GKAP-WT-GFP or with the single point mutation GKAP-S77A-GFP and GKAP-S111A-GFP or with the double point mutation GKAP-AA. …”
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19960
H-89 reduces the signal from RLuc8 in single cells.
Published 2009“…Additional doses of H-89 decrease the signal further. (B) Channel intensity images (top) and pseudocolor images (bottom) of cells corresponding to (A) at t = 15 min (before H-89 addition) and t = 50 min (when signal has reached maximum inhibition).…”