Supplementary Material for: Reduced Mortality Associated with Acute Kidney Injury Requiring Dialysis in the United States by Brown J.R. (4161469)

Regulation of Wnt pathways by <i>O</i>. <i>tsutsugamushi</i> in mononuclear cells and PBMC, data from public repositories. by Thor Ueland (307058)

“…<i>tsutsugamushi</i> compared to non-infected cells (n = 4 in each group) and in patients with scrub typhus compared to murine typhus (MT, Scrub n = 4, typhoid n = 7). *p<0.05, **p<0.01. (E) Correlation between fold change in PBMC (scrub patients vs. controls) and <i>O</i>. …”

Cardiovascular genes are dysregulated in FVB/N KLF2−/− AV region. by Aditi R. Chiplunkar (282141)

“…FVB/N WT and mix WT were designated as100%, and KLF2−/− were compared to WT. (<b>A–C</b>) In E10.5 FVB/N KLF2−/− AV region there is significantly decreased expression of (<b>A</b>) Tbx5 (p = 0.0175), (<b>B</b>) Gata4 (p = 0.0164) and (<b>C</b>) Sox9 (p = 0.019) mRNA compared to FVB/N WT, but Mix WT and Mix KLF2−/− hearts have no differences in expression of these genes. …”

Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands by Rasha Abu-Khudir (239643)

“…After correction for differences in thyroid activation state, 19 genes were exclusively associated with thyroid ectopy, among which genes involved in embryonic development (e.g. <em>TXNIP</em>) and in the Wnt pathway (e.g. …”

Validation of <i>in vivo</i> high confidence Runx1-regulated genes. by Kfir Baruch Umansky (783699)

“…<p>(A) Volcano plot of differentially expressed genes in soleus muscle of 8 weeks old <i>mdx/Runx1</i>^<i>f/f</i> vs. <i>mdx</i> mice. Fold expression change against <i>p</i> value is plotted. …”

Effects of lobeglitazone on insulin resistance and hepatic steatosis in high-fat diet-fed mice - Fig 5 by Bong-Hoi Choi (5173865)

“…All sample groups were visualized by Heat maps of identified hepatic (E) and serum (F) metabolites obtained using UPLC-Q-TOF MS. …”

Table_1_Improving T-DNA Transfer to Tamarix hispida by Adding Chemical Compounds During Agrobacterium tumefaciens Culture.docx by Huimin Zhao (9433532)

“…Treatment with 5-AzaC reduced DNA methylation in Agrobacterium to induce the expression of virulence (vir) family genes, including virA, virB1, virC1, virD2, virD4 virE2, and virG. Spe treatment significantly induced the expression of all the studied genes, including virA, virB1, virC1, virD1, virD2, virD4, virE2, and virG. …”

FIGURE 2 from Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer by Siddharth Mehra (15666660)

“…Western blot analysis demonstrating decreased phosphorylation of AKT (band marked by red arrow) in murine KPC PDAC tumor cell line upon PI3Ki (0–10 μmol/L; <b>E</b>) and Uro A (0–75 μmol/L; <b>F</b>) treatment for 3 hours. …”

Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis by Ada Admin (8524211)

“…We investigated whether inhibiting the NLRP3-inflammasome, through the use of the specific small-molecule NLRP3 inhibitor, MCC950, could reduce inflammation, improve vascular function and protect against diabetes-associated atherosclerosis in the streptozotocin (STZ)-induced diabetic Apolipoprotein knockout (ApoE^-/-) mouse. Diabetes led to a ~4-fold increase in atherosclerotic lesions throughout the aorta, which were significantly attenuated with MCC950 (<i>P</i><0.001). …”

Lake-climate interactions: hydrological forcing and ecological response by Wing Sung (7193081)

“…At Ravn Sø the biota responds to the decreased precipitation in 1975/6 through fewer nutrients entering the lake. …”

Keratinous biomarker of mercury exposure associated with amyotrophic lateral sclerosis risk in a nationwide U.S. study by Angeline S. Andrew (7730159)

“…<i>Results</i>: Compared to the lowest quartile of nail mercury, moderate levels were associated with decreased risk of ALS (<i>P</i> = 4.18e–6). However, the odds of having nail mercury levels above the 90th percentile were 2.3-fold higher among ALS patients compared with controls (odds ratio (OR) = 2.3, 95% confidence interval 1.10–4.58, adjusted for age and smoking status). …”

Genotype Comparison using QPCR at each Differentiation Stage. by Adam S. Arterbery (846608)

“…<p><i>Hhex</i>^<i>-/-</i> HE cells did not show mRNA expression consistent with hepatic differentiation. <b>A-E)</b> Comparison of fold-change in normalized mRNA gene expression using differentiation-stage specific markers. …”

<i>DEK</i> expression in MM cells. by Zihni Onur Çalışkaner (4054018)

“…Black or grey diamonds (D, middle column) indicate samples with ≥ 2-fold increased or decreased <i>DEK</i> expression in CD138^negative cells, respectively. …”

Changes in IKKγ mRNA and protein expression levels in human PBMCs pre-transfected with pre-miR-34c or anti-miR-34c and exposed to HMGB1^+/+ or HMGB1 by Sebnem Unlu (156119)

<i>Ptp4a3</i> is expressed in AOM-DSS derived colon tumors and normal tissue. by Mark W. Zimmerman (395901)

“…<i>Ptp4a3</i> was elevated 3.7-fold (** = p<0.01), while <i>Ptp4a1</i> and <i>Ptp4a2</i> levels were significantly decreased (* = p<0.0001 and p<0.05, respectively) (n = 15, bars  =  SEM). …”

Presentation_1_Early development of infant gut microbiota in relation to breastfeeding and human milk oligosaccharides.pdf by Maciej Chichlowski (362455)

RV adaptation to increased afterload in congenital heart disease and pulmonary hypertension by Mieke M. P. Driessen (5892452)

Image_1_Early development of infant gut microbiota in relation to breastfeeding and human milk oligosaccharides.pdf by Maciej Chichlowski (362455)

Supplementary file 1_Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in sep... by Penglei Yang (8090156)

“…The mean prediction coefficient estimated by the causal forest was 1.00 with a standard error of 0.57, while the differential forest prediction coefficient was 1.64 with a standard error of 0.48, demonstrating the model’s ability to effectively identify differences in the impact of transfusion on survival rates among individuals. …”

Supplementary Material for: GFR-Specific versus GFR-Agnostic Cutoffs for Parathyroid Hormone and Fibroblast Growth Factor-23 in Advanced Chronic Kidney Disease by Canney M. (5218298)