Synthesis and <i>in vitro</i> anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents by Wagdy M. Eldehna (4260952)

“…Compound <b>5l</b> emerged as the most active congener towards both A549 and HCT-116 cell lines with IC₅₀ values equal to 3.22 ± 0.2 and 2.71 ± 0.16 µM, respectively, which are comparable to those of Doxorubicin; 2.93 ± 0.28 and 3.10 ± 0.22, respectively. …”

CSF1R and IL-8 mediated signaling affect PDAC portal blood CTC proliferation, cluster formation, and apoptosis. by Juan Pablo Arnoletti (12275290)

“…Anti-CSF1R treatment gave a 5.2-fold decrease in CTC proliferation in unsorted PortalBMC cultures (p<0.0001). …”

The effect of DDAH1 on VEGF expression in HUVEC. by Ping Zhang (86495)

“…<p>(A) DDAH1 deficiency decreased VEGF protein level in HUVEC. …”

Robotic Thoracic Enucleation of Esophageal Leiomyoma by João Marcelo Lopes Toscano de Brito (11458365)

“…Ten minutes following resection, a PTH level was sent, with a decrease from 130 to 40 pg/mL. …”

Trio overexpression in class I da neurons. by Srividya Chandramouli Iyer (177446)

“…(<b>J</b>) Quantitation of total dendritic length reveals no significant change following Trio overexpression, however with Trio-GEF1 overexpression there is an increase in length as a function of higher levels of dendritic branching, whereas there is a decrease in length with Trio-GEF2 overexpression. …”

Ribosome footprint density patterns suggest categories of translational regulation for longer leader transcripts. by Sarah A. Gilmore (460665)

“…Categories were determined as follows: a: Ribosome density on longer leader region and decreased differential TE for CDS of longer leader transcript, b: Ribosome density on longer leader region and no change in TE for CDS of longer leader transcript, c: Ribosome density on longer leader region and increased differential TE for CDS of longer leader transcript, d: No ribosome density on longer leader region and decreased differential TE for CDS of longer leader transcript, e: No ribosome density on longer leader region and no change in TE for CDS of longer leader transcript, f: No ribosome density on longer leader region and increased differential TE for CDS of longer leader transcript. …”

Qsp1 regulation of binding of Cqs2, Nrg1, and Liv3 to promoters correlates with a change in expression. by Diana K. Summers (9402313)

“…D) Degree of overlap between sets of genes that are differentially bound by a transcription factor and genes that are differentially expressed in a <i>qsp1Δ</i> mutant relative to wild type, and those that are differentially bound by another transcription factor and differentially expressed in <i>qsp1Δ</i> mutants. E) Overlap between gene sets that are differentially bound by all three transcription factors (Liv3, Cqs2, and Nrg1) in the <i>qsp1Δ</i> mutant compared to wild type and genes that are significantly changed, decreased, or increased in the <i>qsp1Δ</i> mutant over wild type.…”

Presentation_1_Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2... by Yongjie Zhang (235244)

Automated, high-throughput phenotyping. by Natasha Oswal (13889773)

“…Meanwhile, their apparent body size decreases until the time of death at which point it increases rapidly (green), plateaus, and then decreases again (gray). c. …”

Summary of different expression patterns for all studied genes and genotypes. by Salah M. H. Gowayed (10492240)

“…The fifth pattern is coloured yellow and includes all the genotypes in which its expression increased after exposure to 50 and 150 mM NaCl and then decreased after exposure to 250 mM NaCl. …”

Yeast essential gene screens for modulators of αSyn toxicity. by Blagovesta Popova (14546)

“…Dark red: target genes; dark blue: protective genes. <b>(E-F)</b> Relative abundance of essential gene hits from yTHC <b>(E)</b> and DAmP screens <b>(F)</b> in functional categories. …”

Suppression of FGF signaling increases Y658 phosphorylation of VE-cadherin and disrupts VE-cadherin/p120-catenin association. by Kunihiko Hatanaka (322096)

“…In each cell, six-seven measuring areas were set at J and C region, respectively, and total six cells were evaluated in each treatment group. The data is shown as a ratio of J/C, mean ± SEM. *: <i>P</i><0.01 vs. …”

Image_1_Both Natural and Induced Anti-Sda Antibodies Play Important Roles in GTKO Pig-to-Rhesus Monkey Xenotransplantation.tif by Hao Feng (54208)

“…Both the overall binding of monkey serum IgM/IgG antibody to GTKO pig PBMCs and CDC against these PBMCs decreased significantly with a progressive reduction in Sda expression, showing a clear dose-effect relationship. …”

Performance on discrimination and reversal tasks are similar for agents with one Q versus G and N matrices. by Kim T. Blackwell (10915047)

“…</b> Dynamics of G and N values for state <i>(Poke port</i>, <i>10 kHz)</i> for a single run. <b>F.</b> Dynamics of β₁ change according to recent reward history; thus, β₁ decreases at the beginning of discrimination, increases as the animal acquires the correct <i>right</i> response, and then decreases to the minimum at reversal. …”

Table_1_Military tactical adaptive decision making during simulated military operational stress is influenced by personality, resilience, aerobic fitness, and neurocognitive functi... by Nicole M. Sekel (14584412)

“…Day 2 (D2) and day 3 (D3) consisted of 48-h of SMOS wherein sleep opportunity and caloric needs were reduced to 50%. Differences in SPEAR total block score from baseline to peak stress (D3 minus D1) were calculated to assess change in military tactical adaptive decision making and groups were stratified based on increase (high adaptors) or decrease (low adaptors) of the SPEAR change score.…”

Swimming endurance training protocol. by Vítor S. Fernandes (21262991)

“…<i>Mib1</i>^<i>flox</i><i>;Tnnt2</i>^<i>Cre</i> cardiomyocytes also showed decreases in outward K⁺ peak currents and currents at the end of depolarizing pulses at potentials ≥−10 mV and ≥−20 mV, respectively, and this was accompanied by a lower charge density at ≥−20 mV. …”

PrP^Sc accumulation in <i>TNFR1^−/−</i> lymph nodes requires LTβR signaling independent of <i>Prnp</i> expression. by Tracy O'Connor (143972)

“…Total mRNA was isolated from spleens (J) or mesenteric lymph nodes (mLN; K) of mice from the indicated treatment groups and analyzed for Prnp expression by Real Time PCR (Mean ± S.E.M.: Spleen – WT-Ig = 100.69±6.74, WT-LTβR-Ig = 46.02±4.30, TNFR1^−/−-Ig = 48.94±0.55, and TNFR1^−/−-LTβR-Ig = 50.11±0.55; mLN – WT-Ig = 106.05±22.54, WT-LTβR-Ig = 101.69±12.88, TNFR1^−/−-Ig = 56.43±3.13, and TNFR1^−/−-LTβR-Ig = 72.35±6.65). …”

Knockdown of <i>LsST6</i> expression interfered with virus entry into midgut epithelial cells of healthy planthoppers. by Faliang Qin (5566298)

“…(A–D) Mean ± SEM of three independent experiments (<i>P</i> < 0.01, one-way ANOVA, LSD test). …”

Revolutionizing Clinical Microbiology Laboratory Organization in Hospitals with <em>In Situ</em> Point-of-Care by Stéphan Cohen-Bacrie (213296)

“…With regard to enterovirus meningitis, the mean length-of-stay of infected patients over 15 years old significantly decreased from 2008 to 2010 compared with 2005 when the POC was not in place (1.43±1.09 versus 2.91±2.31 days; p = 0.0009). …”

RF electromagnetic fields and xenobiotics had significant effects on cellular detected superoxide. by Robert J. Usselman (544611)

“…<p>(<b>A</b>) RF initially decreased the amount of detected superoxide compared with SMF control by 40%. …”