Image_3_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_3_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_1_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_1_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Mitochondrial membrane potential in response to 12 hours of oxygen- glucose deprivation. by Jordan M. Willcox (531224)

“…Control astrocytes indicate astrocytes that were not exposed to OGD and loaded with JC-1 as a control. Scale bar = 50 µm.</p>…”

Combination of Curcumin and DAPT further inhibit proliferation and induce apoptosis. by Dharmalingam Subramaniam (260271)

“…<p>(A) TE cells treated with DAPT (50 µM) and curcumin (30 µM) alone and in combination for 24 h. …”

The Impacts of Human Disturbance on Species Abundance in Pond and Impermeable Habitats by Setareh Rezvani (3113955)

“…</p> <p> Survey method, sweep net: A 50 meter transect was placed. Using a sweep net, the number of invertebrates captured along the 50 meters was measured and recorded. …”

Colony formation assay. by Vincent E. Baldanza (8781671)

“…<p>(A) Abrams, D-17, and HMPOS canine OSA cell lines treated with vehicle control (DMSO), 33% of the respective determined IC₅₀ dose of vismodegib (10 μM for Abrams and HMPOS; 15 μM for D-17), 66% of the respective determined IC₅₀ dose of vismodegib (20 μM for Abrams and HMPOS; 30 μM for D-17), and the full determined IC₅₀ dose of vismodegib (30 μM for Abrams and HMPOS; 45 μM for D-17). …”

V3-peptide depletion of SF162 neutralization. by Ilja Bontjer (426978)

“…^a Values represent 50% neutralization titers in the presence of irrelevant peptide. …”

Survival probability and perceptual history. by Guido Gigante (50145)

Stit and InR cooperatively govern TORC1 activity. by Fergal O'Farrell (435865)

“…<p>Anti-p-dS6K labeling of third instar larval wing discs revealed discrete puncta lying basally within cells. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001612#pbio.1001612.s005" target="_blank">Figure S5</a> for control experiments addressing labeling specificity. …”

Table_2_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The highest proportion of patients (n = 555, 28.88%) were aged 50–59 years. The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Table_5_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The highest proportion of patients (n = 555, 28.88%) were aged 50–59 years. The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Table_4_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The highest proportion of patients (n = 555, 28.88%) were aged 50–59 years. The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Table_1_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The highest proportion of patients (n = 555, 28.88%) were aged 50–59 years. The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Table_3_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The highest proportion of patients (n = 555, 28.88%) were aged 50–59 years. The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Multiple pathways of alveolar macrophage death contribute to pulmonary inflammation induced by silica nanoparticles by Eun-Jung Park (201821)

“…<p>In our previous study, 20 nm-sized amorphous silica nanoparticles (20-SiNPs), but not 50 nm-sized amorphous silica nanoparticles (50-SiNPs), induced pulmonary inflammatory response in rats exposed repeatedly for 14 days (12.5, 25, and 50 μg/time, total six times). …”

Fasting/Refeeding Cycles Prevent Myocardial Dysfunction and Morphology Damage in the Spontaneously Hypertensive Rats by Matheus Fécchio Pinotti (5669387)

“…The level of significance considered was 5% (a = 0.05). Results: The RF rats presented lower cardiac atrophy than R50 in relation to C rats. …”