Deficiency of tau protects against age-dependent neurodegeneration and memory loss measured by deficits in spontaneous alternations in AICD-Tg mice. by Kaushik Ghosal (244754)

“…<p>A. AICD-Tg mice exhibit decreased working memory as measured by deficits in spontaneous alternations at older ages. …”

Data Sheet 2_Heterogeneity of ventricular action potentials in neonatal rat cardiomyocytes and methodological aspects of patch clamp measurements.pdf by Pascal Syren (20762843)

“…In this study, APD₉₀, APD₅₀ and APD₃₀, are decreased at more negative RMP (respectively HMP) values. …”

Data Sheet 1_Heterogeneity of ventricular action potentials in neonatal rat cardiomyocytes and methodological aspects of patch clamp measurements.docx by Pascal Syren (20762843)

“…In this study, APD₉₀, APD₅₀ and APD₃₀, are decreased at more negative RMP (respectively HMP) values. …”

Short-term effects of intravitreal dexamethasone implant (OZURDEX®) on choroidal thickness in patients with naive branch retinal vein occlusion by Hasan Basri Arifoglu (5763800)

“…The mean SFCT after the treatment was 279.64 ± 50.96 µm, significantly thinner than that before intravitreal dexamethasone therapy (p=0.004). …”

Age-Related Differences of the Athlete`s Heart by Kneffel, Zsuzsanna

“…LV hypertrophy is less marked or missing at the older ages (50-80 years). Left ventricle muscle mass (LVMM) is higher in older endurance athletes than in age-matched non-athletes (5) but the difference between athletic and non-athletic subjects decrease continuously or disappears during the ageing. …”
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Achieving Long-Acting Local Analgesia Using an Intelligent Hydrogel Encapsulated with Drug and pH Regulator by Wen Guo (112664)

“…Considering the decrease of solubility of BUP with the increase of pH and the internal acidic environment due to the hydrolysis of PLGA, calcium carbonate (CaCO₃) powder was introduced as a pH regulator. …”

<i>Krt76^mutant</i> mice show barrier function defects and KRT76 stabilises Claudin1 at tight junctions. by Tia DiTommaso (648579)

“…(D) Immunofluorescence analysis of CLDN1 and Ecadherin (ECAD) distribution in wild type and <i>Krt76^tm1a/tm1a</i> mouse dorsal skin. (E) Image quantification at the cellular surface shows an inward shift and a decrease in intensity of CLDN1 not observed with ECAD. …”

AgDscam Is Implicated in Anti-Bacterial Defense by Yuemei Dong (17509)

“…<div><p>(A) RNAi-mediated depletion of AgDscam with a <i>dsRNA</i> fragment complementary to a non-spliced <i>AgDscam</i> exon resulted in decreased mosquito survival after challenge with S. aureus and E. coli compared to the challenged control <i>GFP dsRNA</i>-treated (GFP) mosquitoes. …”

DAF-16 contributes to inhibition of <i>mec-4d</i>–dependent AVM degeneration associated with reduced IIS signaling. by Andrea Calixto (16070)

“…(F–G) <i>mec-4d</i> worms were treated from the time of hatching with the ROS scavenger trolox (100 µm) and ascorbic acid (AA, 50 mM); after 72 hours both somas (F) and axons (G) were protected several fold compared to control nematodes (mean value for each category is shown; error bars [<1%] not included; N = 3 of 30 worms each per group; *p<0.005 by Student's t test compared with control for the SoW and AxW category).…”

Image1_Investigation of methane gas bubble dynamics and hydrate film growth during hydrate formation using 4-D time-lapse synchrotron X-ray computed tomography.tiff by Shadman H. Khan (19431538)

“…The small-size methane bubble population (mean diameter below 10 µm) initially increases at the expense of the larger methane bubble population (mean diameter above 50 µm) due to breakage of the larger bubbles and coalescence of the smaller bubbles. …”

Depletion of Rasa3 impairs EC adhesion turnover. by Patricia Molina-Ortiz (167505)

“…Representative images are shown. Bars = 50 μm. Histograms represent mean ± SD of clustered β1 integrin mean fluorescence intensity (MFI) from 3 independent experiments. …”

DataSheet1_Investigation of methane gas bubble dynamics and hydrate film growth during hydrate formation using 4-D time-lapse synchrotron X-ray computed tomography.docx by Shadman H. Khan (19431538)

“…The small-size methane bubble population (mean diameter below 10 µm) initially increases at the expense of the larger methane bubble population (mean diameter above 50 µm) due to breakage of the larger bubbles and coalescence of the smaller bubbles. …”

Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region by Dagenais, Renée

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Table 1_Analysis of the threshold range of ROS concentration in winter rapeseed of the Brassica napus type.docx by Weiliang Qi (9389353)

“…At half-lethal H₂O₂ concentrations (1.4%–1.5%), the seed germination rate before rehydration is significantly reduced to 10.97% and 9.03%, respectively, but can recover to approximately 50% after rehydration. H₂O₂ concentrations exceeding 2.2% are lethal, resulting in a 0% seed germination rate both before and after rehydration; notably, the post-rehydration germination rate remains below 10%. …”

Image_6_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Data_Sheet_1_Conditioned Medium of Human Menstrual Blood-Derived Endometrial Stem Cells Protects Against MPP+-Induced Cytotoxicity in vitro.docx by Han Li (10885)

“…Our study provided the first evidence that MenSCs-CM has a protective effect on MPP⁺-induced cytotoxicity in various aspects, and firstly showed that MenSCs can release at least 12 kinds of neurotrophic factors to medium, which may contribute to the protective function of MenSCs-CM to treat PD. …”

Image_4_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

The association between observed mobility and quality of life in the near elderly by Jason Shafrin (4379500)

“…This cross-sectional study aimed to assess the association between mobility and quality of life measures in the near elderly.</p><p>Methods</p><p>A prospective observational study of persons aged 50–69 years was conducted. …”

Supplementary Material for: Depressive Symptoms, Subjective Cognitive Decline, and Subjective Sleep Quality Are Associated with Slips and Falls: Data from the Community Health Surv... by Kim J.H. (2867312)

“…<b><i>Results:</i></b> The risk of slips/falls was significantly associated with high levels of depressive symptoms (adjusted OR 1.06, 95% CI: 1.05–1.07) and SCD (adjusted OR 1.33, 95% CI: 1.19–1.50). Regarding each sleep quality component, the adjusted ORs for slips/falls were 1.85 for very poor sleep quality, 1.49 for long sleep latency, 1.04 for <5 h of sleep duration, 1.32 for low sleep efficiency, 2.78 for high sleep disturbance, 1.52 for the use of sleep medication ≥3 times a week, and 1.82 for high daytime dysfunction due to sleep problems compared to the respective good sleep conditions. …”

Restructuring the Crystalline Cellulose Hydrogen Bond Network Enhances Its Depolymerization Rate by Shishir P. S. Chundawat (2163151)

“…Ammonia transformed the naturally occurring crystalline allomorph I_β to III_I, which led to a decrease in the number of cellulose intrasheet hydrogen bonds and an increase in the number of intersheet hydrogen bonds. …”